Brevipil 25 Tablet (10 Tab)

BREVIPIL 25 TABLET

Name

Brand Name: Brevipil 25 Tablet Common Name: Brivaracetam

Composition

Brevipil 25 Tablet contains Brivaracetam 25 mg as its active ingredient.

Uses

Brevipil 25 Tablet is an anti-epileptic medication primarily used for the treatment of partial-onset seizures in patients with epilepsy, one month of age and older. It can be administered alone (monotherapy) or in combination with other anti-epileptic drugs (adjunctive therapy) to help control seizures by reducing abnormal electrical activity in the brain.

Dosage and Administration

Take Brevipil 25 Tablet exactly as prescribed by your doctor. Swallow the tablet whole with a glass of water; do not crush, chew, or break it. It can be taken with or without food. For optimal effectiveness, adhere to your doctor's guidance regarding dosage and timing, ideally taking it at the same time each day to maintain consistent levels in your body. Do not stop taking this medicine suddenly without consulting your doctor, as abrupt discontinuation can worsen seizures.

Side Effects

Common side effects may include:

• Sleepiness or drowsiness
• Dizziness
• Fatigue or overtiredness
• Nausea and vomiting
• Headache
• Irritability, anxiety, or insomnia
• Constipation More serious, though rare, side effects can include allergic reactions (e.g., swelling in the face or throat, difficulty breathing) or psychiatric symptoms (e.g., hallucinations, delusions, depression). Overdose symptoms may include vertigo, balance disorder, double vision, and a slow heart rate.

Precautions

• Driving and Operating Machinery: Brevipil 25 Tablet may cause drowsiness, dizziness, or affect your balance and coordination. Avoid driving or operating heavy machinery until you know how the medicine affects you.
• Alcohol: Avoid consuming alcohol as it can enhance side effects like drowsiness and fatigue.
• Medical Conditions: Inform your doctor if you have liver or kidney problems, as dose adjustments may be necessary. It is not recommended for use in patients with end-stage renal disease undergoing dialysis.
• Pregnancy and Breastfeeding: Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
• Mental Health: Be aware of any unusual changes in mood or behavior, including suicidal thoughts, and consult your doctor immediately if these occur.
• Drug Interactions: Inform your doctor about all other medications, supplements, or herbal products you are taking, especially other anti-epileptic drugs (e.g., carbamazepine, phenytoin), CNS depressants, rifampin, or St. John's wort, as interactions can occur.

Storage

Store Brevipil 25 Tablet in a cool and dry place, away from direct sunlight, and out of sight and reach of children. It should be stored at room temperature, generally below 30°C. Store in its original packaging to protect from moisture.

What is BREVIPIL 25 Tablet used for?

BREVIPIL 25 Tablet is primarily used to manage partial-onset seizures, a type of epilepsy where seizures affect only one part of the brain. It can be used alone (monotherapy) or in combination with other anti-epileptic medicines (adjunctive therapy) to help reduce the frequency and severity of these seizures in patients aged one month and older.

How does BREVIPIL 25 Tablet work?

BREVIPIL 25 Tablet contains brivaracetam, which works by binding with high affinity to synaptic vesicle protein 2A (SV2A) in the brain. This action helps to reduce excessive and abnormal nerve activity, thereby stabilizing brain activity and controlling seizures.

What is the usual dosage for BREVIPIL 25 Tablet?

The dosage of BREVIPIL 25 Tablet is prescribed by your doctor and is personalized based on your condition and response to the medication. It can be taken with or without food, but it is generally advised to take it at the same time each day for consistent levels in your body. Do not crush, chew, or split the tablet; swallow it whole with water.

What are the possible side effects of BREVIPIL 25 Tablet?

Common side effects may include sleepiness, dizziness, fatigue, nausea, and vomiting. Some individuals may also experience headaches, constipation, irritability, anxiety, difficulty sleeping (insomnia), or flu-like symptoms. In rare cases, more serious side effects such as allergic reactions (swelling of the face or throat, difficulty breathing) or psychiatric symptoms (hallucinations, delusions, depression, suicidal thoughts) can occur. Most common side effects are temporary and often lessen as your body adjusts to the medicine.

Is BREVIPIL 25 Tablet safe during pregnancy or breastfeeding?

Caution is advised when taking BREVIPIL 25 Tablet during pregnancy. It is not generally recommended due to limited information on its safety and effects on the unborn baby, and your doctor will weigh the potential benefits against the risks. For breastfeeding mothers, BREVIPIL 25 Tablet may pass into breast milk, so it's important to consult your doctor to decide if you should continue the medication or breastfeeding.

Can BREVIPIL 25 Tablet be taken with other medications?

Yes, but several drug interactions are possible. Concomitant use with other anti-epileptic medicines like carbamazepine or phenytoin may affect medication effects or increase side effects. Central nervous system depressants, such as buprenorphine, propoxyphene, and sodium oxybate, can amplify the sedative effects of Brevipil. Rifampicin can decrease the serum concentration of brivaracetam, potentially requiring a dose adjustment of Brevipil. St John's wort (Hypericum perforatum) can also affect the action of Brevipil. Always inform your doctor about all medicines, supplements, or herbal products you are currently taking.

What precautions should be taken while using BREVIPIL 25 Tablet?

Do not stop taking BREVIPIL 25 Tablet suddenly without consulting your doctor, as abrupt discontinuation can worsen seizures or lead to status epilepticus. Alcohol consumption should be avoided or limited as it can enhance side effects like drowsiness and fatigue. Exercise caution if you have liver or kidney problems, as dose adjustments may be necessary. BREVIPIL 25 Tablet may cause sleepiness, dizziness, or problems with coordination, so avoid driving or operating heavy machinery until you know how the medicine affects you. Monitor for behavioral changes, including suicidal thoughts, and contact your doctor if your mood worsens.

What happens if a dose of BREVIPIL 25 Tablet is missed?

If you miss a dose of BREVIPIL 25 Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one, as this may increase the risk of side effects.

How should BREVIPIL 25 Tablet be stored?

BREVIPIL 25 Tablet should be stored in a cool and dry place, away from direct sunlight. It is typically stored at room temperature (between 10ºC to 25ºC or below 30ºC) and should be protected from light and moisture. Keep the medicine out of sight and reach of children and pets.