Empasov S 25/100

EMPASOV S 25/100 by CIPLA LTD

EMPASOV S 25/100 is a prescription medication combining two active ingredients to manage blood sugar levels in adults with type 2 diabetes mellitus. It is used as an adjunct to diet and exercise for improved glycemic control. This medication also helps reduce the risk of cardiovascular complications in type 2 diabetic patients.

• Name:

  • Common Name: Empagliflozin and Sitagliptin (combination)
  • Brand Name: EMPASOV S 25/100
  • Manufacturer: Cipla Ltd.

• Composition:

  • Empagliflozin: 25 mg
  • Sitagliptin: 100 mg

• Uses:

  • Improve blood sugar control in adults with type 2 diabetes mellitus.
  • Reduce cardiovascular risk in patients with type 2 diabetes.

• Dosage and Administration:

  • Typically, one tablet is taken daily, preferably at the same time each day.
  • Can be taken with or without food.
  • Swallow the tablet whole with water; do not chew, crush, or split it.
  • Dosage adjustments should be made only under a doctor's supervision.

• Side Effects:

  • Common: Vaginal yeast infections, other genital infections, urinary tract infections, increased urination, constipation, rash, itching, nausea, vomiting, diarrhea, stomach upset, headache, dizziness, fatigue, upper respiratory tract infection, fungal infection.
  • Serious (rare): Liver problems (e.g., jaundice), kidney problems, or changes in blood cell counts.

• Precautions:

  • Not recommended during pregnancy and likely unsafe during breastfeeding.
  • Use with caution in patients with kidney or liver impairment. It is not recommended for severe kidney impairment or those on dialysis.
  • Inform your doctor about any pre-existing medical conditions (kidney, liver, heart) and all other medications you are taking.
  • Caution is advised in older adults, dehydrated individuals, or those taking diuretics, as it may increase the risk of low blood pressure.
  • Not for use in type 1 diabetes or diabetic ketoacidosis.
  • Avoid excessive alcohol consumption.
  • Regular monitoring of kidney function and blood sugar levels is recommended.

• Storage:

  • Store below 30°C in a cool, dry place.
  • Keep out of direct sunlight and away from the reach of children and pets.

EMPASOV S 25/100 by CIPLA LTD is a medication commonly prescribed for managing Type 2 Diabetes Mellitus. Here are some frequently asked questions about this medicine:

What is EMPASOV S 25/100 used for?

EMPASOV S 25/100 is primarily used to manage blood sugar levels in adults with Type 2 Diabetes Mellitus when diet and exercise alone are not sufficient for glycemic control. It can also help in reducing cardiovascular risk in patients with Type 2 diabetes.

How does EMPASOV S 25/100 work?

EMPASOV S 25/100 is a combination medication containing Empagliflozin (25 mg) and Sitagliptin (100 mg), which work through different mechanisms. Empagliflozin, an SGLT2 inhibitor, prevents the kidneys from reabsorbing glucose back into the bloodstream, causing excess glucose to be excreted in the urine. Sitagliptin, a DPP-4 inhibitor, increases the levels of incretin hormones, which stimulate insulin release after meals and reduce glucagon secretion, thereby helping to control blood sugar levels.

What is the usual dosage for EMPASOV S 25/100?

The usual dosage is one tablet daily, typically taken in the morning. It can be taken with or without food. The tablet should be swallowed whole with water and not crushed, chewed, or broken. Your doctor may adjust the dosage based on your blood sugar levels and overall health status.

What are the possible side effects of EMPASOV S 25/100?

Common side effects may include nausea, vomiting, diarrhea, stomach upset, headache, dizziness, fatigue, loss of appetite, changes in taste, urinary tract infections, vaginal yeast infections, increased urination, constipation, rash, or itching. More serious, though rare, side effects can include liver problems, kidney problems, pancreatitis, diabetic ketoacidosis, or significant dehydration. It may also cause low blood sugar, especially when used with insulin or sulfonylureas.

Is EMPASOV S 25/100 safe during pregnancy or breastfeeding?

EMPASOV S 25/100 is generally not recommended during pregnancy or breastfeeding. Animal studies have shown harmful effects on the developing baby, and it is unknown if the medication passes into breast milk. It is advisable to consult your doctor for suitable alternatives if you are pregnant, planning to become pregnant, or breastfeeding.

Can EMPASOV S 25/100 be taken with other medications?

It is important to inform your doctor about all medications, supplements, and herbal remedies you are currently taking, as EMPASOV S 25/100 can interact with certain drugs. For instance, co-administration with diuretics may increase the risk of dehydration or low blood pressure. When taken with insulin or sulfonylureas, the risk of low blood sugar increases, and dose adjustments may be necessary.

What precautions should be taken while using EMPASOV S 25/100?

Before starting EMPASOV S 25/100, inform your doctor about any pre-existing medical conditions, especially kidney or liver problems, heart conditions, or a history of pancreatitis or urinary tract infections. This medicine is not recommended for individuals with Type 1 diabetes or diabetic ketoacidosis. Maintain a healthy lifestyle, including a balanced diet and regular physical activity, and avoid excessive alcohol consumption. Regular monitoring of kidney function and blood sugar levels is also recommended. Staying well-hydrated is crucial, as the medication can increase urination and lead to dehydration.

What happens if a dose of EMPASOV S 25/100 is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should EMPASOV S 25/100 be stored?

EMPASOV S 25/100 should be stored in a cool, dry place, away from direct sunlight, and out of reach of children and pets. It is typically recommended to store it below 30°C.