Rozucor B 20 Tab

ROZUCOR B 20 TAB

ROZUCOR B 20 TAB is a medication manufactured by Torrent Pharmaceuticals Ltd., designed to manage high cholesterol levels and reduce cardiovascular risks.

• Name

  • Common Name: Rozucor B 20 Tablet
  • Brand Name: ROZUCOR B 20 TAB

• Composition ROZUCOR B 20 Tablet contains a combination of two active ingredients:

  • Rosuvastatin (20 mg)
  • Bempedoic acid (180 mg) Rosuvastatin is a statin that inhibits an enzyme crucial for cholesterol production in the liver, thereby lowering "bad" cholesterol (LDL) and triglycerides and raising "good" cholesterol (HDL). Bempedoic acid also decreases cholesterol production in the liver and enhances the removal of LDL cholesterol from the blood.

• Uses ROZUCOR B 20 Tablet is prescribed for:

  • Lowering high levels of low-density lipoprotein (LDL) cholesterol (bad cholesterol) and triglycerides.
  • Increasing high-density lipoprotein (HDL) cholesterol (good cholesterol).
  • Reducing the risk of serious cardiovascular events such as heart attack and stroke.
  • Managing high blood lipid levels when diet and exercise alone are insufficient.
  • Slowing the progression of atherosclerosis, which is the buildup of plaque in blood vessels.
  • Treating hereditary types of high cholesterol, including heterozygous and homozygous familial hypercholesterolemia.

• Dosage and Administration

  • Take ROZUCOR B 20 Tablet exactly as prescribed by your doctor.
  • It is typically taken once daily.
  • The tablet can be taken with or without food, but it is advisable to take it at the same time each day for best results.
  • Swallow the tablet whole with a glass of water; do not chew, crush, or break it.

• Side Effects

  • Common Side Effects: Headache, stomach pain, dizziness, weakness, muscle pain (myalgia), nausea, constipation, abdominal pain, fatigue, upper respiratory tract infection, muscle spasm, back pain, and pain in extremities.
  • Serious Side Effects (less common but require medical attention): Severe muscle damage (rhabdomyolysis), liver problems (indicated by symptoms like dark urine or yellow skin/eyes), increased blood sugar levels, and memory loss.

• Precautions

  • Inform your doctor if you have allergies to Rosuvastatin, Bempedoic acid, or any other ingredients.
  • Not recommended during pregnancy or breastfeeding due to potential harm to the fetus or infant. Women of childbearing age should use effective contraception.
  • Caution is advised in patients with liver or kidney disease; it is not recommended in cases of moderate to severe liver impairment or severe kidney impairment.
  • Diabetic patients should monitor blood sugar levels regularly, as the medicine may increase them.
  • Limit alcohol consumption, as it may increase the risk of liver damage.
  • Avoid consuming excessive grapefruit juice.
  • Inform your doctor about all other medications you are taking, especially immunosuppressants (like cyclosporine), other cholesterol-lowering agents (like gemfibrozil), anticoagulants (like warfarin), and certain HIV protease inhibitors.
  • Report any unexplained muscle pain or weakness immediately to your doctor.
  • Not recommended for children as safety and efficacy have not been established.

• Storage

  • Store in a cool and dry place, away from direct sunlight.
  • Keep out of reach and sight of children.
  • Maintain storage temperatures below 25°C or 30°C.

What is ROZUCOR B 20 Tablet used for?

ROZUCOR B 20 Tablet is primarily used to lower high levels of "bad cholesterol" (low-density lipoprotein or LDL) and triglycerides in the blood. It also helps increase "good cholesterol" (high-density lipoprotein or HDL). By managing cholesterol levels, this medication reduces the risk of serious cardiovascular events such as heart attacks, strokes, and the progression of atherosclerosis (hardening of the arteries).

How does ROZUCOR B 20 Tablet work?

ROZUCOR B 20 Tablet is a combination medication containing Rosuvastatin and Bempedoic acid.

• Rosuvastatin belongs to a class of drugs called statins. It works by inhibiting an enzyme in the liver (HMG-CoA reductase) that is crucial for cholesterol production. This action reduces the amount of LDL cholesterol the liver makes and increases the removal of existing LDL cholesterol from the bloodstream.
• Bempedoic acid decreases cholesterol production in the liver by blocking another enzyme called adenosine triphosphate-citrate lyase (ACL), further enhancing the removal of LDL cholesterol from the blood. Together, these components work synergistically to lower LDL cholesterol more effectively.

What is the usual dosage for ROZUCOR B 20 Tablet?

ROZUCOR B 20 Tablet typically contains Rosuvastatin 20 mg and Bempedoic acid 180 mg. It should be taken as prescribed by your doctor, usually once daily, with or without food. For best results, it's often recommended to take it at the same time each day. The tablet should be swallowed whole with water and not broken, crushed, or chewed. Your doctor will determine the appropriate dosage and any adjustments based on your medical condition and response to treatment.

What are the possible side effects of ROZUCOR B 20 Tablet?

Common side effects can include headache, muscle pain (myalgia), weakness, nausea, abdominal pain, dizziness, constipation, and fatigue. More serious, though less common, side effects may include increased liver enzymes, increased blood sugar levels (especially in diabetic patients), and severe muscle damage (rhabdomyolysis), which can manifest as unusual muscle pain, weakness, or dark urine and may lead to kidney problems. Liver injury, characterized by yellowing of the skin or eyes, dark urine, or severe stomach pain, is also a possible rare side effect. Allergic reactions like skin rash, itching, or swelling of the face, lips, or throat should also be reported immediately. If any side effects persist or become severe, it is important to consult your doctor.

Is ROZUCOR B 20 Tablet safe during pregnancy or breastfeeding?

No, ROZUCOR B 20 Tablet is contraindicated during pregnancy as it can cause harm to the fetus. Women of childbearing potential should use effective birth control methods while taking this medication. If you become pregnant, stop taking the medicine immediately and inform your doctor. Similarly, it is not recommended during breastfeeding because the medication can pass into breast milk and may cause side effects in the infant. Consult your doctor for alternative treatment options if you are breastfeeding.

Can ROZUCOR B 20 Tablet be taken with other medications?

ROZUCOR B 20 Tablet can interact with several other medications. It is important to inform your doctor about all prescription and over-the-counter medicines, as well as any herbal supplements you are taking.

• Immunosuppressants (e.g., cyclosporine) and HIV protease inhibitors (e.g., ritonavir, lopinavir, atazanavir) can increase the levels of ROZUCOR B 20 Tablet in your body, raising the risk of side effects, particularly muscle problems.
• Taking it with other cholesterol-lowering agents like gemfibrozil, fenofibrate, or niacin may increase the risk of muscle damage.
• Anticoagulants such as warfarin can have their blood-thinning effects enhanced when taken with this medicine.
• Antacids containing aluminum and magnesium should be taken at least 2 hours after ROZUCOR B 20 Tablet to avoid reduced absorption.

What precautions should be taken while taking ROZUCOR B 20 Tablet?

• Allergies: Inform your doctor if you have any known allergies to rosuvastatin, bempedoic acid, or any other ingredients in the tablet.
• Alcohol Consumption: Limit or avoid alcohol as it can increase the risk of liver damage and may also raise triglyceride levels.
• Liver and Kidney Conditions: Use with caution if you have liver or kidney problems. It is not recommended for moderate to severe liver or severe kidney impairment. Your doctor may perform regular liver function tests.
• Diabetes: If you have diabetes, monitor your blood sugar levels closely, as this medication may increase them.
• Muscle Pain: Immediately report any unexplained muscle pain, tenderness, or weakness to your doctor, especially if accompanied by fever or dark urine, as this could indicate a serious muscle condition.
• Diet and Lifestyle: Maintain a low-fat diet and engage in regular exercise for optimal treatment effectiveness.
• Driving/Operating Machinery: This medicine may cause dizziness, so exercise caution when driving or operating machinery until you know how it affects you.
• Grapefruit Juice: Avoid excessive consumption of grapefruit juice.

What happens if a dose of ROZUCOR B 20 Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should ROZUCOR B 20 Tablet be stored?

Store ROZUCOR B 20 Tablet in a cool and dry place, away from direct sunlight and moisture. Keep it out of reach and sight of children. Do not use the medicine past its expiry date.