Paxrot Cr Ls Tab

PAXROT CR LS TAB by TRIPADA HEALTHCARE is a medication primarily prescribed for various mood and anxiety disorders. It is manufactured by Tripada Healthcare Pvt Ltd..

• Name

  • Brand Name: PAXROT CR LS TAB
  • Common Names: Paxrot CR LS 12.5/0.25mg ER Tablet. Other related formulations include Paxrot CR 12.5mg Tablet CR and Paxrot CR 25 Tablet.

• Composition PAXROT CR LS TAB contains a combination of two active ingredients:

  • Paroxetine: 12.5mg
  • Clonazepam: 0.25mg

• Uses This medication is primarily used to treat various psychiatric conditions by helping to balance brain chemicals. It is prescribed for:

  • Depression
  • Anxiety disorder
  • Obsessive-compulsive disorder (OCD)
  • Panic disorder
  • Social anxiety disorder
  • Post-traumatic stress disorder (PTSD)
  • Premenstrual dysphoric disorder (PMDD)

• Dosage and Administration PAXROT CR LS TAB should be taken as prescribed by a doctor. It can be taken with or without food, but taking it with food may help reduce stomach upset. The tablet should be swallowed whole with a glass of water and not crushed, broken, or chewed. The dosage may be started at a lower level and gradually increased by the doctor. It is crucial not to stop the treatment suddenly without consulting a doctor, as this can lead to withdrawal symptoms.

• Side Effects Common side effects may include:

  • Nausea, vomiting, diarrhea, or constipation
  • Fatigue, weakness, or drowsiness
  • Dry mouth
  • Loss of appetite
  • Increased sweating
  • Dizziness, confusion, nervousness, tremors, or insomnia (difficulty sleeping)
  • Sexual side effects such as decreased sexual drive, delayed ejaculation, and erectile dysfunction
  • Memory impairment, uncoordinated body movements Serious side effects, though rare, can include suicidal thoughts or actions, serotonin syndrome, abnormal bleeding, severely elevated mood (mania), seizures, glaucoma, and low sodium levels.

• Precautions

  • Contraindications: Do not use if allergic to any components. It should not be used with monoamine oxidase inhibitors (MAOIs) or within 14 days of discontinuing them. Concomitant use with antipsychotic medications like thioridazine or pimozide is also contraindicated.
  • Medical Conditions: Use with caution in patients with kidney disease, liver disease, heart problems, epilepsy (seizure disorder), diabetes, or glaucoma. Inform your doctor if you have a history of mania or bipolar disorder, as antidepressants can increase the risk of manic episodes.
  • Pregnancy and Breastfeeding: PAXROT CR LS TAB is highly unsafe to use during pregnancy (Category D for Paroxetine) and is probably unsafe during breastfeeding. Consult your doctor if you are pregnant, planning pregnancy, or breastfeeding.
  • Children: Not recommended for individuals under 18 years of age due to an increased risk of side effects like suicidal thoughts and aggression.
  • Alcohol and Driving: Avoid consuming alcohol as it may worsen side effects. This medicine may cause decreased alertness, affect vision, or cause sleepiness and dizziness, so avoid driving or operating machinery.
  • Discontinuation: Do not stop treatment suddenly; the dose should be gradually reduced under medical supervision to avoid withdrawal symptoms.

• Storage Store PAXROT CR LS TAB in a cool and dry place, away from direct sunlight. Maintain a temperature between 10ºC to 25ºC or below 30ºC. Keep the medicine out of reach and sight of children.

What is PAXROT CR LS TAB used for?

PAXROT CR LS TAB, which contains Paroxetine and Clonazepam, is primarily used for the treatment of depression. The Paroxetine component alone is also used for anxiety disorder, obsessive-compulsive disorder (OCD), phobia, post-traumatic stress disorder, and panic disorder.

How does PAXROT CR LS TAB work?

PAXROT CR LS TAB combines two active ingredients: Paroxetine and Clonazepam. Paroxetine is a selective serotonin reuptake inhibitor (SSRI) that increases the levels of serotonin, a natural chemical messenger in the brain, to improve mood and alleviate symptoms of depression and anxiety. Clonazepam, a benzodiazepine, works by increasing the levels of gamma-amino-butyric-acid (GABA), a calming chemical in the brain, which helps to reduce anxiety and panic.

What is the usual dosage for PAXROT CR LS TAB?

The dosage of PAXROT CR LS TAB is determined by your doctor based on your medical condition and response to treatment. It is typically taken once daily, often in the morning, and can be taken with or without food. The tablets should be swallowed whole and not crushed, broken, or chewed. Your doctor may start you on a lower dose and gradually increase it. Do not alter the dose or stop taking the medication without consulting your doctor, as this could worsen your condition or lead to withdrawal symptoms.

What are the possible side effects of PAXROT CR LS TAB?

Common side effects of PAXROT CR LS TAB may include nausea, fatigue, dry mouth, loss of appetite, increased sweating, dizziness, nervousness, tremors, difficulty sleeping (insomnia), constipation, memory impairment, uncoordinated body movements, drowsiness, low sexual desire, and delayed ejaculation. If any side effects persist or worsen, it is important to consult your doctor.

Is PAXROT CR LS TAB safe during pregnancy or breastfeeding?

PAXROT CR LS TAB (specifically its Paroxetine component) is considered highly unsafe during pregnancy as it may cause harm to the fetus, including potential abnormalities or developmental issues of the heart. It is also likely unsafe during breastfeeding because the medication can pass into breast milk and potentially harm the baby. Always consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Can PAXROT CR LS TAB be taken with other medications?

Caution is advised when taking PAXROT CR LS TAB with other medications, as interactions can occur. It should not be taken with monoamine oxidase inhibitors (MAOIs) or if you have taken MAOIs within the last 14 days. Other medications that may interact include other antidepressants, certain antipsychotic medicines (such as thioridazine or pimozide), blood thinners, cimetidine, St. John's wort, tamoxifen (as PAXROT CR LS TAB may reduce its effectiveness and increase the risk of breast cancer recurrence), theophylline, tramadol, L-tryptophan, and certain headache medications (triptans). Always inform your doctor about all medications you are currently taking.

What precautions should be taken while using PAXROT CR LS TAB?

• Alcohol: Avoid consuming alcohol while on this medication, as it can cause excessive drowsiness, calmness, and worsen other side effects.
• Driving and Machinery: This medicine may cause decreased alertness, affect vision, or lead to sleepiness and dizziness, so avoid driving or operating heavy machinery.
• Medical Conditions: Inform your doctor if you have epilepsy, diabetes, liver or kidney disease, heart problems, glaucoma, or a history of suicidal thoughts.
• Children: PAXROT CR LS TAB is not recommended for individuals under 18 years due to an increased risk of side effects like suicidal thoughts, aggression, and anger.
• Diabetics: The medication may alter blood sugar levels, necessitating adjustments to insulin or other antidiabetic medications.
• Worsening Mood/Suicidal Thoughts: Contact your doctor immediately if you experience a sudden worsening of mood or any thoughts of self-harm.

What happens if a dose of PAXROT CR LS TAB is missed?

If you miss a dose of PAXROT CR LS TAB, take it as soon as you remember. However, if it is nearly time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should PAXROT CR LS TAB be stored?

PAXROT CR LS TAB should be stored in a cool and dry place, away from direct sunlight, and kept out of the reach and sight of children. It is generally recommended to store it at temperatures between 10ºC to 25ºC or below 30ºC.