Naltrust 50 Tab

NALTRUST 50 TAB by TRIPADA HEALTHCARE

• Name: Naltrust 50 Tablet (Brand name: Naltrust)
• Composition: Each film-coated tablet contains 50 mg of Naltrexone Hydrochloride. Naltrexone is an opioid antagonist.
• Uses: Naltrust 50 Tablet is primarily used in the management of alcohol dependence (chronic alcoholism) and opioid dependence. It works by blocking the euphoric effects of opioids and alcohol, thereby reducing cravings and helping patients abstain. It is typically used as part of a comprehensive treatment program that includes counseling and social support.
• Dosage and Administration: The typical recommended dosage for adults is 50 mg once daily. For opioid dependence, treatment may start with a lower dose of 25 mg (half tablet) for the first day, increasing to 50 mg if no withdrawal symptoms occur. It can be taken with or without food. Patients should not stop taking the medicine until the full course is completed as prescribed by the doctor.
• Side Effects: Common side effects may include nausea, vomiting, headache, nervousness, anxiety, sleep disorders (insomnia, sleepiness), restlessness, abdominal pain, joint pain, muscle pain, and weakness. Serious side effects can include liver problems (e.g., hepatitis), severe allergic reactions, and increased risk of opioid overdose if opioids are taken during or after treatment.
• Precautions:
  • Naltrust 50 Tablet is contraindicated in patients with current physiological opioid dependence, acute opioid withdrawal, or a positive urine screen for opioids. Patients must be opioid-free for at least 7-10 days before starting treatment.
  • Caution is advised for patients with liver or kidney disease; regular monitoring of liver function tests is recommended.
  • This medicine may cause dizziness or drowsiness, so patients should avoid driving or operating machinery until they know how it affects them.
  • Taking large quantities of opioids to overcome the blocking action of Naltrexone can lead to acute opioid intoxication, which can be life-threatening.
  • Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.
• Storage: Store in a cool and dry place, away from sunlight, at temperatures between 10ºC to 25ºC or below 30ºC. Keep out of the sight and reach of children.

NALTRUST 50 TAB by TRIPADA HEALTHCARE is a medication that contains Naltrexone, an opioid antagonist used in the management of alcohol and opioid dependence.

What is NALTRUST 50 TAB used for?

NALTRUST 50 TAB (Naltrexone 50mg) is primarily used to treat alcohol use disorder (AUD) and opioid use disorder (OUD). It helps individuals who have already stopped drinking alcohol or using opioids to maintain abstinence by reducing cravings and blocking the euphoric effects of these substances. It is most effective when used as part of a comprehensive treatment plan that includes counseling and support.

How does NALTRUST 50 TAB work?

NALTRUST 50 TAB works as an opioid receptor antagonist. It binds to the mu-opioid receptors in the brain, blocking the effects of both external opioids (like heroin or pain medications) and alcohol. By occupying these receptors, it prevents the activation of reward pathways, thereby eliminating the euphoric and sedative effects that opioids and alcohol can produce. This action helps to reduce cravings and makes substance use less pleasurable.

What is the usual dosage for NALTRUST 50 TAB?

For alcohol use disorder, the typical dosage is 50 mg once daily. For opioid use disorder, treatment usually begins with a lower dose of 25 mg once daily for a few days. If no withdrawal symptoms occur, the dosage is then increased to 50 mg once daily. This medication should be taken as prescribed by your doctor, usually at the same time each day.

What are the possible side effects of NALTRUST 50 TAB?

Common side effects of NALTRUST 50 TAB can include nausea, headache, dizziness, fatigue, anxiety, nervousness, abdominal pain or cramps, trouble sleeping, and reduced appetite. More serious, though less common, side effects can include liver injury (symptoms like yellowing skin/eyes, severe stomach pain, dark urine), depression, and suicidal thoughts. Report any severe or persistent side effects to your healthcare provider immediately.

Is NALTRUST 50 TAB safe during pregnancy or breastfeeding?

The safety of NALTRUST 50 TAB during pregnancy is not fully clear, and it may not be the first-choice treatment for AUD or OUD in pregnant individuals. However, some studies suggest that Naltrexone may be a potential option with reassuring outcomes, but more research is needed. If you are pregnant or planning to become pregnant, discuss the risks and benefits with your doctor. During breastfeeding, naltrexone is minimally excreted into breast milk and is generally considered safe. However, it's always best to consult your healthcare provider to weigh the benefits against any potential risks for your baby.

Can NALTRUST 50 TAB be taken with other medications?

NALTRUST 50 TAB has significant interactions, particularly with opioids. It should not be taken if you are currently using prescription or illicit opioids, including opioid pain medications, some cough syrups, or anti-diarrhea medications that contain opioids, as it can cause severe withdrawal symptoms. You must be opioid-free for at least 7 to 10 days before starting NALTRUST 50 TAB. Inform your doctor about all medications, supplements, and herbal products you are taking, as interactions can also occur with drugs like disulfiram, acamprosate, lofexidine, some antidepressants, blood thinners, and diabetes medications.

What precautions should be taken while using NALTRUST 50 TAB?

Before starting NALTRUST 50 TAB, you must be completely free of opioids for at least 7 to 10 days to avoid precipitated withdrawal. Your doctor may perform tests to confirm this. Naltrexone can affect liver function, so regular monitoring of liver function tests may be advised, especially if you have existing liver disease. Do not self-treat coughs, colds, pain, or diarrhea with over-the-counter medications that might contain opioids. Carry an identification card stating that you are taking naltrexone, as it can affect emergency care. Naltrexone may cause dizziness or drowsiness, so avoid driving or operating machinery until you know how it affects you.

What happens if a dose of NALTRUST 50 TAB is missed?

If you miss a dose of NALTRUST 50 TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double or extra dose to make up for a missed one. Consistency in dosing is important for maintaining the therapeutic effect.

How should NALTRUST 50 TAB be stored?

NALTRUST 50 TAB should be stored at room temperature, ideally between 20°C and 25°C (68°F and 77°F). It can tolerate temperatures between 15°C and 30°C (59°F and 86°F) for shorter periods. Keep the medication in a cool, dry place, away from excessive heat, moisture, and direct light, and out of the reach of children and pets.