Nitrobact 100 Mg Capsule (10 Cap)

NITROBACT 100 MG CAPSULE

Nitrobact 100 mg Capsule is an antibiotic medication manufactured by Mankind Pharma Ltd., primarily used for treating and preventing bacterial infections of the urinary tract.

Composition

Nitrobact 100 mg Capsule contains Nitrofurantoin 100 mg as its active ingredient. Nitrofurantoin works by disrupting bacterial DNA production, thereby inhibiting bacterial growth and preventing them from reproducing.

Uses

Nitrobact 100 mg Capsule is prescribed for the treatment and prevention of bacterial infections affecting the urinary tract (UTIs). This includes conditions such as:

• Simple urinary tract infections
• Bladder infections (cystitis)
• Kidney infections It can also be used long-term to prevent recurrent UTIs in both adults and children over 12 years old.

Dosage and Administration

• Adults: The typical recommended adult dosage for treating UTIs is 50 to 100 mg taken orally four times a day, with food or milk.
• The capsule should be swallowed whole with a glass of water; it should not be crushed or chewed.
• Taking the medicine with food helps improve absorption and minimizes gastrointestinal side effects like nausea and vomiting.
• It is crucial to complete the entire course of treatment as prescribed by your doctor, even if symptoms improve, to ensure complete eradication of the bacteria and prevent antibiotic resistance.

Side Effects

Common side effects associated with Nitrobact 100 mg Capsule include:

• Nausea
• Vomiting
• Diarrhea
• Flatulence (gas)
• Headache
• Dizziness
• Loss of appetite
• Urine discoloration (dark yellow or brown)

More serious, but less common, side effects can include:

• Lung inflammation (especially with long-term use)
• Liver problems (jaundice, hepatitis)
• Peripheral neuropathy (numbness, tingling, pain in hands or feet)
• Hemolytic anemia
• Allergic reactions (skin rash, itching, swelling, breathing difficulties)

Precautions

• Pregnancy: Nitrobact 100 mg Capsule is contraindicated in pregnant patients at term (38-42 weeks). Consult a doctor if you are pregnant or planning pregnancy.
• Breastfeeding: Trace amounts of the medicine may pass into breast milk and can cause anemia in infants. Discuss with your doctor before breastfeeding.
• Kidney Impairment: Use with caution in patients with kidney issues and is contraindicated in severe kidney disease (creatinine clearance < 60 mL/min).
• Liver Impairment: Use with caution in patients with liver issues.
• G6PD Deficiency: Administer with caution in patients with G6PD deficiency due to an increased risk of hemolytic anemia.
• Diabetes: Regular monitoring of glucose levels is necessary as this medicine could affect blood sugar control.
• Alcohol: While no known interaction exists, it is advisable to avoid alcohol consumption as it may increase the risk of side effects.
• Drug Interactions:
  • Antacids containing magnesium trisilicate (e.g., Gaviscon, Digene) may hamper nitrofurantoin absorption.
  • Oral contraceptives may have decreased effectiveness.
  • Urine alkalinizers (e.g., potassium citrate) can increase the risk of nitrofurantoin toxicity.
• Driving and Machine Use: The medicine may cause dizziness, so avoid driving or operating machinery until you feel better.

Storage

Store Nitrobact 100 mg Capsule in a dry place, protected from moisture. Keep the temperature steady, not exceeding 30°C, and shield the medicine from direct light to maintain its effectiveness. Always keep it out of reach of children. Ensure use before its expiry date.

NITROBACT 100 MG CAPSULE, containing nitrofurantoin, is an antibiotic primarily used to treat and prevent bacterial infections of the urinary tract.

What is NITROBACT 100 MG CAPSULE used for?

NITROBACT 100 MG CAPSULE is an antibiotic primarily used to treat and prevent bacterial urinary tract infections (UTIs), including bladder infections (cystitis) and kidney infections. It is effective against various bacteria such as E. coli, enterococci, and staphylococci. It is important to note that this medicine only treats bacterial infections and will not work for viral infections like the common cold or flu.

How does NITROBACT 100 MG CAPSULE work?

This medicine contains nitrofurantoin, which works by killing bacteria. It achieves this by entering the bacterial cells and interfering with their DNA production, which is essential for bacterial growth and reproduction. This targeted action helps to inhibit bacterial growth effectively, primarily concentrating its effects within the urinary tract.

What is the usual dosage for NITROBACT 100 MG CAPSULE?

The typical adult dosage for treating urinary tract infections is 50 to 100 mg taken orally four times a day, or 100 mg as slow-release capsules twice a day, usually with food or milk. For preventing recurrent UTIs, a dose of 50 mg to 100 mg once a day at night may be prescribed. It is crucial to always follow your doctor's specific instructions regarding the dosage and to complete the entire course of medication, even if your symptoms improve. Taking the capsule with food helps improve absorption and minimize stomach upset.

What are the possible side effects of NITROBACT 100 MG CAPSULE?

Common side effects include nausea, vomiting, diarrhea, headache, dizziness, flatulence, and loss of appetite. A common and harmless effect of this medication is that it may turn your urine dark yellow or brown; this will disappear once you stop taking the medicine. More serious, but less common, side effects can include skin rash, fever, chills, burning or tingling sensations (peripheral neuropathy), hepatitis, hemolytic anemia, and pulmonary reactions. If you experience any severe or persistent side effects, or notice signs of a fungal or yeast infection (thrush), consult your doctor immediately.

Is NITROBACT 100 MG CAPSULE safe during pregnancy or breastfeeding?

NITROBACT 100 MG CAPSULE is generally not recommended during late pregnancy (at term, during labor, or delivery) due to a potential risk of hemolytic anemia in the newborn. In other stages of pregnancy, it can be used if clearly prescribed by your doctor after discussing the potential risks and benefits. When breastfeeding, trace amounts of the medicine may pass into breast milk, which could lead to anemia in infants. Therefore, it should be used with caution, and consulting your doctor before taking it while breastfeeding is advised. It is contraindicated for nursing preterm infants or G-6-PD-deficient infants during their first month.

Can NITROBACT 100 MG CAPSULE be taken with other medications?

Yes, NITROBACT 100 MG CAPSULE can interact with certain medications. Antacids containing magnesium trisilicate (e.g., Gaviscon, Digene) can reduce its absorption. It may also decrease the effectiveness of oral contraceptives (birth control pills). Additionally, urine alkalinizers like potassium citrate can increase the risk of nitrofurantoin toxicity. Inform your doctor about all medications, supplements, and herbal remedies you are currently taking to avoid potential interactions.

What precautions should be taken while using NITROBACT 100 MG CAPSULE?

Do not take this medicine if you are allergic to nitrofurantoin or any of its components. Caution is advised if you have kidney disease (it's contraindicated in severe kidney impairment), liver disease, glucose-6-phosphate dehydrogenase (G6PD) deficiency, diabetes, anemia, or lung disease. This medicine may cause dizziness or drowsiness, so avoid driving or operating machinery until you know how it affects you. While there's no known direct interaction with alcohol, it's generally advisable to limit or avoid alcohol consumption while on antibiotics. For long-term use, your doctor will monitor for potential side effects such as pulmonary toxicity or peripheral neuropathy. If you experience severe or bloody diarrhea, contact your doctor.

What happens if a dose of NITROBACT 100 MG CAPSULE is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not take a double dose to make up for a missed dose.

How should NITROBACT 100 MG CAPSULE be stored?

Store NITROBACT 100 MG CAPSULE in a dry place, protected from moisture and direct light, at a temperature not exceeding 30°C. Keep the medicine out of reach of children and pets. Always check the expiry date and use the medicine before it expires.