Metride 1 Mg Tablet (15 Tab)

METRIDE 1 MG TABLET (15 TAB) by TORRENT PHARMACEUTICALS LTD.

Name: Metride 1 Tablet is the brand name, containing a combination of Glimepiride and Metformin.

Composition: Each tablet contains Glimepiride USP 1 mg and Metformin Hydrochloride USP 500 mg (as sustained release form).

Uses: Metride 1 Tablet is primarily used for the management of type 2 diabetes mellitus in adults. It is prescribed when diet, exercise, and a single anti-diabetic agent alone are insufficient to control blood sugar levels. This medication helps lower high blood sugar levels by improving how the body uses insulin and reducing glucose production in the liver, thereby reducing the risk of diabetes-related complications.

Dosage and Administration: Metride 1 Tablet should be taken orally, exactly as prescribed by your doctor, usually once daily, preferably with a meal or the first main meal of the day. The tablet should be swallowed whole with a glass of water and should not be crushed or chewed. Dosage adjustments are made based on individual blood sugar levels and response to treatment.

Side Effects:

• Common Side Effects: Hypoglycemia (low blood sugar), nausea, vomiting, diarrhea, abdominal pain, headache, and metallic taste.
• Serious Side Effects: Lactic acidosis (rare but serious), severe allergic reactions (skin rash, hives), and liver inflammation (jaundice). Long-term use may also lead to Vitamin B12 deficiency.

Precautions:

• Metride 1 Tablet is contraindicated in individuals with type 1 diabetes mellitus, diabetic ketoacidosis, or severe kidney or liver disease.
• Caution is advised for pregnant or breastfeeding women; consult your doctor.
• Avoid excessive alcohol consumption, as it increases the risk of lactic acidosis.
• Regular monitoring of blood sugar levels is crucial.
• Inform your doctor about all other medications, supplements, and herbal products being taken to avoid potential drug interactions.

Storage: Keep Metride 1 Tablet at room temperature below 30°C. Protect the product from light and moisture, and store it out of reach of children. Always check the expiry date before use.

What is Metride 1 MG Tablet used for?

Metride 1 MG Tablet is primarily used to manage Type 2 Diabetes Mellitus in adults. It is prescribed when diet, exercise, and a single anti-diabetic medication are not sufficient to adequately control blood sugar levels. This medication helps improve blood glucose control when used alongside a proper diet and regular exercise.

How does Metride 1 MG Tablet work?

Metride 1 MG Tablet contains two active ingredients: Glimepiride and Metformin. Glimepiride works by stimulating the beta cells in the pancreas to produce and release more insulin, a hormone that helps lower blood sugar. Metformin, a biguanide, acts by reducing the amount of glucose produced by the liver, decreasing sugar absorption from the intestines, and improving the body's sensitivity to insulin, allowing cells to use blood glucose more effectively. Together, these actions help to lower and stabilize blood sugar levels.

What is the usual dosage for Metride 1 MG Tablet?

Metride 1 MG Tablet is typically taken once daily, usually with breakfast or the first main meal of the day. The exact dosage will be determined by your doctor based on your individual blood sugar levels and how you respond to the medication. It is crucial to follow your doctor's instructions precisely and not to adjust the dosage without consulting them.

What are the possible side effects of Metride 1 MG Tablet?

Common side effects may include low blood sugar (hypoglycemia), nausea, vomiting, diarrhea, abdominal pain, headache, and dizziness.

A serious but rare side effect, particularly associated with metformin, is lactic acidosis. Symptoms can include muscle pain or weakness, dizziness, tiredness, a feeling of cold in arms and legs, difficulty breathing, stomach pain, or a slow heart rate. This risk is higher in individuals with kidney disease, older patients, or those who consume large amounts of alcohol.

Is Metride 1 MG Tablet safe during pregnancy or breastfeeding?

Metride 1 MG Tablet is generally not recommended during pregnancy. Insulin is often preferred for managing diabetes during pregnancy as it provides more stable blood sugar control and does not cross the placenta.

For breastfeeding mothers, Metride 1 MG Tablet is usually not recommended. While metformin levels in breast milk are minimal and it is considered safe for breastfeeding, glimepiride's passage into breast milk and its potential effect on the baby's blood sugar are not fully known, and it could potentially lower the baby's blood sugar. It is important to discuss the benefits and risks with your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Can Metride 1 MG Tablet be taken with other medications?

Metride 1 MG Tablet can interact with various medications, which may affect its effectiveness or increase the risk of side effects like hypoglycemia or lactic acidosis. These include other anti-diabetic medicines (like insulin), certain antibiotics (e.g., quinolones, chloramphenicol), blood pressure medications (e.g., ACE inhibitors, ARBs), NSAIDs, corticosteroids, thiazide diuretics, oral contraceptives, and certain heart or thyroid medications. Always inform your doctor or pharmacist about all other medicines, supplements, and herbal products you are taking to prevent potential interactions.

What precautions should be taken while taking Metride 1 MG Tablet?

It is very important to regularly monitor your blood sugar levels and HbA1c (a measure of long-term blood sugar control) as directed by your doctor. You should also carefully follow the special meal plan and exercise regimen your doctor provides. Avoid consuming alcohol while taking this medication, as it can significantly increase the risk of low blood sugar and lactic acidosis. Caution is advised for individuals with kidney disease, liver disease, G6PD deficiency, heart disease, or during periods of stress such as fever, infection, trauma, or surgery, as these conditions may affect blood sugar control and require dose adjustments.

What happens if a dose of Metride 1 MG Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this can lead to severe side effects like dangerously low blood sugar.

How should Metride 1 MG Tablet be stored?

Store Metride 1 MG Tablet in a closed container at room temperature, ideally below 30 degrees C (86 degrees F), away from heat, moisture, and direct light. Do not freeze the medication. Keep it out of reach of children and pets. Dispose of any outdated or unused medication properly as advised by your healthcare professional.