Oxetol Xr 450 Mg Tablet (10 Tab)

OXETOL XR 450 MG TABLET

OXETOL XR 450 MG TABLET is an extended-release anticonvulsant medication manufactured by Sun Pharma Laboratories Ltd..

• Name:
  • Brand Name: OXETOL XR 450 MG TABLET
  • Common Name: Oxcarbazepine Extended Release
• Composition:
  • Active Ingredient: Oxcarbazepine 450 mg
• Uses: OXETOL XR 450 MG TABLET is primarily used to manage and control seizures associated with epilepsy. It is effective in treating partial-onset seizures in adults and children aged 6 years and older. It can be used as monotherapy (alone) or as adjunctive therapy (in combination with other antiepileptic drugs). The medication works by stabilizing abnormal electrical activity in the brain and calming the nerves.
• Dosage and Administration: This medicine should be taken exactly as prescribed by a doctor. The extended-release formulation allows for once-daily dosing, but it is often recommended to take it twice daily. It can be taken with or without food, but taking it at the same time each day is beneficial. Do not chew, crush, or break the tablet; it should be swallowed whole with water. For adults, the initial dose might be 600 mg daily in two divided doses, gradually increased up to a maximum of 2,400 mg daily. For children above 6 years, the dosage is weight-based, typically starting at 8 to 10 mg/kg daily in two divided doses, increasing to a maximum of 46 mg/kg daily.
• Side Effects: Common side effects may include dizziness, drowsiness, headache, nausea, vomiting, fatigue, blurred vision, double vision (diplopia), unsteadiness, and low blood sodium levels (hyponatremia). Serious side effects, though less common, can include severe skin reactions (like Stevens-Johnson syndrome), liver problems, pancreatitis, changes in mood or behavior (e.g., depression, suicidal thoughts), and increased seizure frequency.
• Precautions: Inform your doctor about any kidney or liver problems, heart conditions, or a history of low sodium levels. Caution is advised with alcohol consumption as it can increase sedative effects. This medicine may decrease the effectiveness of oral contraceptives. Do not stop taking the medication suddenly, as it can increase seizure frequency; dosage should be gradually reduced under medical supervision. Driving or operating machinery should be avoided until you know how the medicine affects you due to potential dizziness or drowsiness. Pregnant or breastfeeding women should consult their doctor.
• Storage: Store in a cool, dry place, away from direct sunlight and moisture, preferably below 30°C. Keep out of reach of children and pets.

What is Oxetol XR 450 mg Tablet used for?

Oxetol XR 450 mg Tablet is primarily used to manage and prevent partial seizures in adults and children aged 6 years and older who have epilepsy. It can be prescribed as the sole treatment (monotherapy) or in combination with other anti-epileptic medications (adjunctive therapy). This medication may also be used to manage certain types of nerve pain.

How does Oxetol XR 450 mg Tablet work?

This medicine contains oxcarbazepine, an anticonvulsant or anti-epileptic drug. It works by stabilizing the abnormal electrical activity in the brain that causes seizures. It achieves this by blocking voltage-sensitive sodium channels in nerve cells, which helps to prevent the excessive firing of these cells and reduce the spread of seizure activity. The extended-release (XR) formulation allows for a steady release of the medication over a prolonged period.

What is the usual dosage for Oxetol XR 450 mg Tablet?

The dosage is determined by your doctor based on your condition and response to the medication. For adults, a typical starting dose might be 300 mg once or twice daily, gradually increased by 300 mg per day weekly until an optimal dose, usually ranging from 900 mg to 3600 mg per day, is achieved. For children, the dosage is calculated based on their weight and is generally lower than for adults, with smaller increments during titration. The tablet should be swallowed whole with water and should not be crushed, chewed, or broken. It can be taken with or without food, preferably at the same time(s) each day.

What are the possible side effects of Oxetol XR 450 mg Tablet?

Common side effects include dizziness, drowsiness, headache, nausea, vomiting, blurred or double vision, fatigue, and unsteadiness. Some people may also experience low sodium levels in the blood (hyponatremia). More serious, but less common, side effects can include severe skin reactions (such as Stevens-Johnson syndrome), liver problems, inflammation of the pancreas, changes in mood or behavior (including depression or suicidal thoughts), and blood disorders. If any side effects persist or become severe, consult your doctor immediately.

Is Oxetol XR 450 mg Tablet safe during pregnancy or breastfeeding?

Pregnancy: Oxetol XR 450 mg Tablet should be used with caution during pregnancy as it may potentially harm the unborn baby, especially during the first trimester. It is generally prescribed only if the potential benefits outweigh the risks, under strict medical supervision. Women of childbearing age should use effective contraception, as this medication can reduce the effectiveness of hormonal birth control.

Breastfeeding: This medicine is generally not recommended while breastfeeding because its active ingredient, oxcarbazepine, can pass into breast milk and may cause side effects in the infant, such as excessive sleepiness or poor weight gain. Consult your doctor if you are breastfeeding.

Can Oxetol XR 450 mg Tablet be taken with other medications?

Oxetol XR 450 mg Tablet can interact with other medications. It can decrease the effectiveness of hormonal contraceptives, so additional non-hormonal birth control methods should be considered. It may also interact with other anti-epileptic drugs (e.g., phenytoin, carbamazepine), certain antidepressants, diuretics (which can further lower sodium levels), and non-steroidal anti-inflammatory drugs (NSAIDs). Always inform your doctor about all prescription, over-the-counter, and herbal medications you are currently taking to avoid potential interactions.

What precautions should be taken while taking Oxetol XR 450 mg Tablet?

Avoid consuming alcohol while taking this medicine, as it can increase drowsiness and other side effects. Do not stop taking the medication abruptly without consulting your doctor, as sudden discontinuation can increase seizure frequency. Your doctor will advise on gradually reducing the dosage if needed. Inform your doctor about any pre-existing conditions, especially kidney or liver problems, low sodium levels, depression, or heart issues. Be aware of potential severe skin reactions; seek immediate medical attention if you develop a rash, blisters, or peeling skin. Due to potential dizziness or drowsiness, avoid driving or operating heavy machinery until you understand how the medication affects you. Taking it with food can help minimize stomach upset.

What happens if a dose of Oxetol XR 450 mg Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should Oxetol XR 450 mg Tablet be stored?

Store Oxetol XR 450 mg Tablet in a cool, dry place, typically below 30°C, away from direct sunlight and moisture. Keep it in an airtight container and out of the sight and reach of children and pets to maintain its effectiveness and prevent accidental ingestion.