Macpod O Tablet (10 Tab)

Name: MACPOD O TABLET

Composition: MACPOD O TABLET contains a combination of two active antibiotic ingredients:

• Cefpodoxime Proxetil (200 mg)
• Ofloxacin (200 mg)

Uses: MACPOD O TABLET is a broad-spectrum antibiotic prescribed to treat various bacterial infections. It is effective against:

• Respiratory tract infections, including pneumonia, bronchitis, pharyngitis, sinusitis, and tonsillitis
• Urinary tract infections (UTIs)
• Ear infections (acute otitis media)
• Skin and soft tissue infections
• Sexually transmitted diseases (e.g., gonorrhoea)
• Typhoid fever It works by inhibiting bacterial cell wall synthesis (Cefpodoxime) and blocking bacterial DNA replication (Ofloxacin), thereby killing the bacteria and preventing the spread of infection. This medicine is not effective against viral infections like the common cold or flu.

Dosage and Administration: Take MACPOD O TABLET as advised by your physician. It can be taken with or without food, but it's recommended to take it at a fixed time daily for better efficacy. Swallow the tablet whole with a glass of water; do not crush or chew it. Complete the entire course of treatment as prescribed by your doctor, even if symptoms improve, to prevent the infection from returning and to avoid antibiotic resistance. Do not exceed the recommended dose.

Side Effects:

• Common Side Effects: Stomach pain, nausea, vomiting, diarrhea, dizziness, headache, and/or pain in the neck and lower legs. These usually resolve as your body adjusts to the medicine.
• Serious Side Effects: Seek immediate medical attention if you experience a rash, itchy skin, swelling of the face and mouth, or difficulty breathing, as these could indicate an allergic reaction. Inform your doctor if diarrhea persists or if you find blood in your stools.

Precautions:

• Allergies: Do not take if you are allergic to Cefpodoxime, Ofloxacin, other cephalosporin antibiotics (e.g., cephalexin), or any other ingredients in the tablet.
• Pregnancy and Breastfeeding: Not recommended during pregnancy as it may harm the fetus. Generally not recommended for breastfeeding women as it may pass into breast milk. Consult your doctor.
• Medical Conditions: Inform your doctor if you have stomach/intestinal diseases (especially colitis), blood clotting disorders, kidney disease, liver disease, epilepsy, tendinitis, myasthenia gravis, or a history of heart rhythm disorders (Long QT Syndrome).
• Alcohol: Avoid alcohol consumption as it may increase drowsiness.
• Driving/Operating Machinery: May cause dizziness or blurred vision; avoid driving or operating machines if affected.
• Drug Interactions: Inform your doctor about all other medications, herbal preparations, and over-the-counter medicines you are taking to avoid potential interactions, especially with uricosurics (e.g., probenecid), anticoagulants (e.g., warfarin), bronchodilators (e.g., theophylline), and oral antidiabetics.

Storage: Store MACPOD O TABLET in a tightly closed container, at an ideal room temperature not exceeding 25°C or below 30°C. Keep it away from direct light and moisture. Always keep this medicine out of the sight and reach of children.

Here are some frequently asked questions about MACPOD O TABLET (10 TAB) by MACLEODS PHARMACEUTICALS LTD.

What is Macpod O Tablet used for?

MACPOD O TABLET is an antibiotic primarily used to treat various bacterial infections in adults. These include infections of the respiratory tract (such as pneumonia, bronchitis, pharyngitis, tonsillitis, and sinusitis), urinary tract infections, ear infections, skin infections, and typhoid fever. It is not effective against viral infections like the common cold or flu.

How does Macpod O Tablet work?

MACPOD O TABLET is a combination of two antibiotic drugs: Cefpodoxime and Ofloxacin. Cefpodoxime works by preventing the formation of the bacterial cell wall, which is essential for the bacteria's survival. Ofloxacin inhibits DNA gyrase, an enzyme necessary for bacterial DNA replication, transcription, and repair, thereby stopping bacterial growth and multiplication. Together, they kill the bacteria and help prevent the spread of infection.

What is the usual dosage for Macpod O Tablet?

The dosage of MACPOD O TABLET is determined by your doctor based on your condition and the severity of the infection. It is typically advised to take the tablet as prescribed, with or without food, and at a fixed time each day for optimal effectiveness. You should not exceed the recommended dosage. It is crucial to complete the full course of treatment, even if symptoms improve, to ensure the infection is completely cured and to prevent antibiotic resistance.

What are the possible side effects of Macpod O Tablet?

Common side effects associated with MACPOD O TABLET may include nausea, vomiting, diarrhea, stomach pain, headache, and dizziness. Other reported side effects include indigestion, pain in the lower legs, neck pain, vaginal itching, abdominal pain, and skin rash. If any of these side effects persist or worsen, it is advisable to consult your doctor.

Is Macpod O Tablet safe during pregnancy or breastfeeding?

MACPOD O TABLET is generally not recommended during pregnancy as it may cause harm to the fetus. For breastfeeding women, it is also generally not advised as it may pass into breast milk. In both cases, your doctor will only prescribe it if the potential benefits outweigh the risks. It is important to consult your healthcare provider before taking this medication if you are pregnant or breastfeeding.

Can Macpod O Tablet be taken with other medications?

MACPOD O TABLET can interact with certain medications. It is important to inform your doctor about all medicines you are taking, including prescription, non-prescription, and herbal medicines.

• Antacids and Iron Supplements: These may reduce the absorption of Ofloxacin or Cefpodoxime, respectively. It is recommended to take antacids and iron supplements at least 2 hours before or 2 hours after taking MACPOD O TABLET.
• NSAIDs (Nonsteroidal Anti-inflammatory Drugs): Medicines like ibuprofen or fenbufencan, when taken with MACPOD O TABLET, may increase the chance of fits or gastrointestinal side effects.
• Warfarin: Ofloxacin may interact with blood thinners like warfarin, potentially increasing the risk of bleeding.
• Probenecid: This medication may slow down the elimination of Cefpodoxime, leading to increased levels of the antibiotic in the body.
• Theophylline: Concomitant use with theophylline may lead to increased levels of theophylline in the blood.

What precautions should be taken while taking Macpod O Tablet?

Several precautions should be observed when taking MACPOD O TABLET:

• Allergies: Avoid taking this medicine if you are allergic to Cefpodoxime, Ofloxacin, other cephalosporin antibiotics, or any of its components.
• Pre-existing Medical Conditions: Inform your doctor if you have conditions such as tendinitis or tendon rupture, myasthenia gravis, epilepsy, liver or kidney problems, stomach/intestinal diseases (especially colitis), or blood clotting disorders.
• Alcohol: Avoid consuming alcohol as it may cause increased dizziness and drowsiness.
• Driving/Operating Machinery: This medicine may cause dizziness, sleepiness, or blurred vision. Do not drive or operate heavy machinery if you experience these effects.
• Photosensitivity: MACPOD O TABLET may make your skin sensitive to sunlight or UV radiation.
• Complete Course: Always complete the entire course of treatment as prescribed by your doctor, even if you feel better, to prevent the infection from returning and to avoid antibiotic resistance.

What happens if a dose of Macpod O Tablet is missed?

If you miss a dose of MACPOD O TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses together to make up for a missed dose.

How should Macpod O Tablet be stored?

MACPOD O TABLET should be stored in a tightly closed container at an ideal room temperature, generally not exceeding 25°C or 30°C. Keep the medicine away from direct light and moisture, and always out of the sight and reach of children.