Zovirax 400 Mg Tablet ( 10 Tab )

ZOVIRAX 400 MG TABLET

ZOVIRAX 400 MG TABLET is an antiviral medication manufactured by GlaxoSmithKline Pharmaceuticals Limited.

• Name: The brand name is ZOVIRAX, and the common name for its active ingredient is Aciclovir (also spelled Acyclovir).

• Composition: Each tablet contains 400 mg of aciclovir as the active ingredient. Inactive ingredients include magnesium stearate, microcrystalline cellulose, povidone, and sodium starch glycolate.

• Uses: ZOVIRAX 400 MG TABLET is prescribed to treat viral infections caused by herpes viruses. These include:

  • Chickenpox
  • Shingles (herpes zoster)
  • Cold sores (herpes labialis)
  • Genital herpes and other herpes simplex infections, including initial and recurrent episodes.
  • It also helps prevent these infections from returning, especially in individuals with weakened immune systems.

• Dosage and Administration: The dosage and duration of treatment depend on the specific medical condition and should always be followed as advised by a healthcare professional. Tablets can be swallowed whole with water or dispersed in a quarter glass of water. Early initiation of treatment, preferably at the first signs of infection, is recommended for optimal effectiveness. For shingles, a common adult dose is 800 mg five times daily for 7 to 10 days. For chronic suppressive therapy of recurrent genital herpes, 400 mg twice daily for up to 12 months may be prescribed.

• Side Effects:

  • Common Side Effects: Headache, dizziness, nausea, vomiting, diarrhea, rash, and fatigue.
  • Serious Side Effects: Though rare, these may include allergic reactions (hives, swelling of face/lips/tongue/throat, difficulty breathing), confusion, hallucinations, kidney injury (decreased urination, swelling of ankles/hands/feet), and seizures.

• Precautions:

  • Inform your doctor if you have kidney disease, liver conditions, a weak immune system, or are pregnant or breastfeeding.
  • Stay well-hydrated by drinking plenty of fluids, as this helps prevent dehydration and potential kidney damage.
  • Avoid sexual contact if you have active genital herpes lesions to prevent transmission.
  • Disclose all other medications, including over-the-counter drugs, vitamins, and herbal supplements, as some medicines like probenecid, cimetidine, and mycophenolate mofetil can interact with Aciclovir.
  • Caution is advised when driving or operating machinery, as ZOVIRAX can cause dizziness.

• Storage: Store ZOVIRAX 400 MG TABLET in its original packaging in a cool, dark, and dry place where the temperature stays below 30°C. Keep out of sight and reach of children. Do not store in the bathroom or near a sink, and protect from heat and dampness.

Here are some frequently asked questions about ZOVIRAX 400 MG TABLET:

What is ZOVIRAX 400 MG TABLET used for?

ZOVIRAX 400 MG TABLET, containing aciclovir, is an antiviral medication primarily used to treat infections caused by the herpes virus. These infections include shingles (herpes zoster), cold sores (herpes labialis), genital herpes infections, and chickenpox. It helps to reduce the severity, pain, and duration of outbreaks, and can also be used to prevent frequent recurrences of herpes simplex infections.

How does ZOVIRAX 400 MG TABLET work?

ZOVIRAX 400 MG TABLET works by using its active ingredient, aciclovir, to stop the herpes virus from multiplying in human cells. Aciclovir achieves this by interfering with the viral DNA, which is essential for the virus to replicate, thereby reducing the length and severity of the viral outbreak.

What is the usual dosage for ZOVIRAX 400 MG TABLET?

The dosage of ZOVIRAX 400 MG TABLET varies depending on the condition being treated. For shingles, a common dosage is two 400 mg tablets (800 mg) taken five times daily (every four hours while awake) for seven days. For initial episodes of genital herpes, the dosage might be 200 mg five times a day for 10 days, or 400 mg three times a day for 7-10 days. For chronic suppression of recurrent genital herpes, a typical dose is 400 mg twice daily for up to 12 months. For chickenpox, adults and children over 40 kg usually take 800 mg four times a day for five days. Your doctor will determine the appropriate dose and duration for your specific condition. Tablets can be swallowed whole with water or dispersed in about 50 mL of water.

What are the possible side effects of ZOVIRAX 400 MG TABLET?

Common side effects can include headache, dizziness, nausea, vomiting, diarrhea, fatigue, fever, skin rash, and stomach pain. More serious, but rare, side effects that require immediate medical attention may include hives, blistering or peeling skin rash, yellowing of the skin or eyes (jaundice), unusual bruising or bleeding, confusion, hallucinations, or signs of kidney problems like producing little to no urine, painful urination, or swelling in the feet or ankles.

Is ZOVIRAX 400 MG TABLET safe during pregnancy or breastfeeding?

ZOVIRAX (aciclovir) is generally considered safe for use during pregnancy, and studies have not indicated an increased risk of birth defects. It may be prescribed by a healthcare provider, especially in cases of primary genital herpes infection or varicella pneumonia, where the benefits outweigh potential risks. Aciclovir passes into breast milk in small amounts, but it is unlikely to cause adverse effects in breastfed infants. Consult your doctor or health visitor if you have any concerns while breastfeeding.

Can ZOVIRAX 400 MG TABLET be taken with other medications?

ZOVIRAX can interact with certain other medications. Inform your doctor or pharmacist about all prescription, over-the-counter medicines, vitamins, and herbal supplements you are taking. Some medications that may interact with ZOVIRAX include probenecid (used for gout), cimetidine, certain fluid tablets (diuretics), and mycophenolate mofetil (an immunosuppressant). These interactions can affect the concentration of aciclovir in the body or the effectiveness of other drugs.

What precautions should be taken while taking ZOVIRAX 400 MG TABLET?

It is important to drink plenty of fluids while taking ZOVIRAX to help prevent dehydration and potential kidney damage. Start treatment as soon as possible after the first appearance of symptoms for the best results. Do not take this medicine if you are allergic to aciclovir or valaciclovir. Exercise caution if you have kidney problems or are over 65 years of age, as dose adjustments may be necessary, and you might be more prone to side effects. Herpes infections are contagious, even during treatment, so avoid contact with infected areas and wash your hands frequently. If you have genital herpes, practice safe sex and avoid sexual activity when sores are present.

What happens if a dose of ZOVIRAX 400 MG TABLET is missed?

If you miss a dose of ZOVIRAX 400 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you have forgotten to take more than one dose, it's best to contact your doctor or pharmacist for advice.

How should ZOVIRAX 400 MG TABLET be stored?

Store ZOVIRAX 400 MG TABLET in its original packaging in a cool, dark, and dry place, ideally where the temperature stays below 30°C (or 25°C). Avoid storing it in the bathroom, near a sink, or in a car on hot days, as heat and dampness can affect the medication. Always keep ZOVIRAX and all other medicines out of the sight and reach of children.