Pregaba D 75/20 Mg Capsule (10 Cap)

PREGABA D 75/20 MG CAPSULE

PREGABA D 75/20 MG CAPSULE is a combination medication manufactured by Torrent Pharmaceuticals Ltd., designed for comprehensive management of neuropathic pain and associated conditions.

• Name:

  • Brand Name: PREGABA D 75/20 MG CAPSULE

• Composition:

  • Each capsule contains Pregabalin 75 mg and Duloxetine 20 mg (sustained release). Pregabalin is an anticonvulsant and analgesic, while Duloxetine is a selective serotonin and norepinephrine reuptake inhibitor (SSNRI).

• Uses: PREGABA D 75/20 MG CAPSULE is primarily prescribed for the treatment of:

  • Neuropathic pain (nerve pain), including diabetic peripheral neuropathy, post-herpetic neuralgia, and pain from spinal cord injury.
  • Fibromyalgia.
  • Anxiety disorders.
  • Adjunctive therapy in epilepsy.

• Dosage and Administration:

  • This medicine should be taken orally as directed by a healthcare professional, with or without food.
  • Swallow the capsule whole; do not chew, crush, or break it.
  • It is generally taken once or twice a day, preferably at the same time daily to maintain consistent medicine levels.
  • A doctor may start with a low dose and gradually increase it based on individual response. Do not stop the medication abruptly to avoid withdrawal symptoms.

• Side Effects: Common side effects may include:

  • Drowsiness, dizziness, headache
  • Nausea, dry mouth, constipation
  • Weight gain, increased appetite
  • Blurred vision, difficulty concentrating
  • Fatigue, difficulty sleeping
  • Less common but serious side effects can include suicidal thoughts or changes in mood/behavior.

• Precautions:

  • Avoid alcohol consumption, as it can increase drowsiness and other side effects, and may increase the risk of liver damage.
  • This medication may cause dizziness and drowsiness; avoid driving or operating heavy machinery until you know how it affects you.
  • Inform your doctor if you have kidney or liver problems, diabetes (as it may affect blood sugar levels), glaucoma, a history of depression, mood changes, or suicidal thoughts.
  • Use with caution in patients with angioedema episodes or severe cardiovascular disease.
  • Not recommended for use in children below 18 years of age.
  • Pregnant or breastfeeding mothers should consult their doctor before use.

• Storage:

  • Store PREGABA D 75/20 MG CAPSULE in a cool, dry place, away from direct sunlight and moisture.
  • Keep it out of reach of children and pets. Store below 30°C.

PREGABA D 75/20 MG CAPSULE by TORRENT PHARMACEUTICALS LTD. is a combination medication containing Pregabalin (75 mg) and Duloxetine (20 mg). It is primarily used for the management of neuropathic pain, including diabetic neuropathic pain and fibromyalgia.

Here are some frequently asked questions about PREGABA D 75/20 MG CAPSULE:

What is PREGABA D 75/20 MG CAPSULE used for?

PREGABA D 75/20 MG CAPSULE is used to treat neuropathic pain, which is pain caused by nerve damage. This includes conditions such as diabetic neuropathic pain (nerve pain associated with diabetes) and fibromyalgia (widespread musculoskeletal pain). It may also be used to improve depressive symptoms associated with major depressive disorder and for generalized anxiety disorder.

How does PREGABA D 75/20 MG CAPSULE work?

This medicine combines two active ingredients: Pregabalin and Duloxetine. Pregabalin is an anticonvulsant that works by controlling calcium channel activity in nerve cells, which reduces the release of neurotransmitters that send pain signals. Duloxetine is a serotonin-norepinephrine reuptake inhibitor (SNRI) that increases the levels of chemical messengers (serotonin and norepinephrine) in the brain. These actions together help to regulate pain signals, improve mood, and alleviate anxiety.

What is the usual dosage for PREGABA D 75/20 MG CAPSULE?

The dosage and duration of treatment are determined by your doctor based on your condition and response to therapy. It is crucial to follow your doctor's instructions. The capsules should be swallowed whole with a glass of water, with or without food, and should not be crushed, chewed, or broken. Do not stop taking this medicine abruptly without consulting your doctor, as it can lead to withdrawal symptoms.

What are the possible side effects of PREGABA D 75/20 MG CAPSULE?

Common side effects can include nausea, constipation, headache, dry mouth, increased sweating, loss of appetite, dizziness, drowsiness, blurred vision, difficulty sleeping, fatigue, and weight gain. Some patients may also experience tingling or numbness, reduced sex drive, or uncoordinated body movements. These side effects often resolve over time. However, if any side effects persist or worsen, you should inform your doctor. More serious side effects, though rare, can include suicidal thoughts, severe allergic reactions (e.g., hives, difficulty breathing, swelling), and kidney problems.

Is PREGABA D 75/20 MG CAPSULE safe during pregnancy or breastfeeding?

PREGABA D 75/20 MG CAPSULE is generally not recommended during pregnancy unless the potential benefits outweigh the risks. Duloxetine in late pregnancy may cause short-term withdrawal symptoms or breathing problems in the baby. Pregabalin's safety during pregnancy is unclear, with some studies showing potential harm.

For breastfeeding, it is generally not recommended to use this medicine. Both pregabalin and duloxetine pass into breast milk in small amounts. While some data suggest duloxetine can be safely administered while breastfeeding, and pregabalin has been used with no reported adverse effects in some infants, it's best to consult your doctor for safer alternatives or to weigh the risks and benefits.

Can PREGABA D 75/20 MG CAPSULE be taken with other medications?

It is important to inform your doctor about all medicines, supplements, or herbal products you are currently taking to avoid potential drug interactions. Taking PREGABA D 75/20 MG CAPSULE with other central nervous system depressants (like opioids, benzodiazepines, or sedatives) can increase drowsiness, dizziness, and difficulty concentrating. It should also not be taken with certain antidepressants (like other SSRIs or MAOIs) due to the risk of severe adverse effects. Concurrent use with ACE inhibitors may increase the risk of angioedema.

What precautions should be taken with PREGABA D 75/20 MG CAPSULE?

Avoid consuming alcohol while taking this medicine, as it can increase side effects like drowsiness, dizziness, and blurred vision, and may increase the risk of liver damage. Do not drive or operate heavy machinery until you know how this medication affects you, as it can cause dizziness, drowsiness, and blurred vision. Inform your doctor if you have liver or kidney disease, seizures, mania, bipolar disorder, glaucoma, bleeding disorders, heart conditions, or diabetes. This medicine may increase suicidal thoughts, especially in children and young adults, so monitor for mood changes. Do not stop the medication suddenly, as it can lead to withdrawal symptoms.

What happens if a dose is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should PREGABA D 75/20 MG CAPSULE be stored?

Store PREGABA D 75/20 MG CAPSULE at room temperature, typically between 20°C to 25°C (68°F to 77°F), protected from moisture and light. Keep the capsules in their original packaging and out of reach of children.