Zoxan Eye Drops -10ml

ZOXAN Eye Drops 0.3% w/v

ZOXAN Eye Drops, manufactured by FDC LTD, is an ophthalmic solution primarily used to treat bacterial infections of the eye.

• Name:

  • Common Name: Ciprofloxacin Ophthalmic Solution
  • Brand Name: ZOXAN Eye Drops

• Composition:

  • Active Ingredient: Ciprofloxacin 0.3% w/v (as Ciprofloxacin Hydrochloride)
  • Preservative: Benzalkonium Chloride 0.006% w/v
  • Other Ingredients: Disodium edentate, Mannitol, Sodium acetate (anhydrous), Glacial acetic acid, Sodium hydroxide, Hydrochloric acid, Water for Injections.

• Uses: ZOXAN Eye Drops are prescribed for the treatment of various bacterial eye infections.

  • Corneal ulcers
  • Bacterial conjunctivitis (pink eye)
  • Other superficial bacterial infections of the eye and adnexa, such as blepharitis and keratitis.

• Dosage and Administration: This medicine is for ocular use only. The specific dosage and duration depend on the type and severity of the infection and should be followed as prescribed by a doctor.

  • For Corneal Ulcers (Adults and children over 2 years):
    • Day 1: Two drops into the affected eye every 15 minutes for the first 6 hours, then two drops every 30 minutes for the remainder of the day.
    • Day 2: Two drops into the affected eye hourly.
    • Day 3-14: Two drops into the affected eye every four hours. Treatment may continue for longer than 14 days at the discretion of the physician.
  • For Bacterial Conjunctivitis and Superficial Ocular Infections (Adults and children over 2 years):
    • Initially, one or two drops into the affected eye(s) every two hours while awake for two days.
    • Then, one or two drops every four hours while awake until the bacterial infection is resolved.
  • Administration Instructions: Wash hands before use. Tilt head back, pull down the lower eyelid to form a pocket, and instill the drops without touching the eye or surrounding areas with the dropper tip to prevent contamination. If using other topical ophthalmic medications, instill them 5 to 15 minutes apart.

• Side Effects: Common side effects may include:

  • Eye discomfort, irritation, burning, or stinging sensation
  • Eye redness (ocular hyperemia)
  • Blurred vision (temporary)
  • Eyelid swelling or itching
  • Feeling of something in the eye (foreign body sensation)
  • Bad taste in the mouth (dysgeusia)
  • Corneal deposits Serious side effects are rare but can include allergic (hypersensitivity) reactions with symptoms like rash, itching, swelling of the face or tongue, or shortness of breath. Tendon inflammation or rupture may occur, especially in elderly patients or those on corticosteroids.

• Precautions:

  • Do not wear contact lenses (hard or soft) during treatment of an eye infection. If necessary, wait at least 15 minutes after using the drops before reinserting lenses.
  • Avoid driving or operating machinery if vision is temporarily blurred after instillation.
  • Inform your doctor if you have liver or kidney disease.
  • Prolonged use may lead to the overgrowth of non-susceptible organisms.
  • Discontinue use and consult a doctor if pain, swelling, or inflammation of tendons occurs.
  • Use with caution in pregnant or breastfeeding women; consult a doctor.
  • Not recommended for children under 1 year unless prescribed by a physician.

• Storage:

  • Store at a temperature not exceeding 25°C to 30°C.
  • Protect from light.
  • Keep the container tightly sealed when not in use.
  • Discard the product 30 days after opening the vial.
  • Keep out of sight and reach of children.

Zoxan Eye Drops are an antibiotic medication primarily used to treat bacterial infections of the eyes. This includes conditions such as bacterial conjunctivitis (pink eye), corneal ulcers, blepharitis (inflammation of the eyelids), and keratitis (inflammation of the cornea).

How does Zoxan Eye Drops work?

Zoxan Eye Drops contain Ciprofloxacin, a fluoroquinolone antibiotic. It works by inhibiting specific bacterial enzymes, DNA gyrase and topoisomerase IV, which are vital for bacterial DNA replication and repair. By blocking these processes, Ciprofloxacin effectively kills the bacteria causing the eye infection. The drops also contain Benzalkonium Chloride, which acts as an antimicrobial preservative.

What is the usual dosage for Zoxan Eye Drops?

The dosage of Zoxan Eye Drops varies depending on the type and severity of the eye infection, and should always be followed as prescribed by your doctor. For bacterial conjunctivitis, a common regimen involves instilling one or two drops into the affected eye every two hours while awake for two days, followed by one or two drops every four hours while awake for the next five days. For corneal ulcers, the dosing schedule is typically more frequent in the initial stages of treatment.

What are the possible side effects of Zoxan Eye Drops?

Common side effects include temporary eye irritation, redness, discomfort, and blurred vision. You might also experience eyelid swelling or itching, a foreign body sensation in the eye, headache, or a taste disturbance. Occasionally, white crystal-like corneal deposits may form, especially with frequent use for corneal ulcers, but these are generally harmless and usually clear up after treatment. If any side effects persist or worsen, consult your doctor.

Is Zoxan Eye Drops safe during pregnancy or breastfeeding?

Zoxan Eye Drops should be used with caution during both pregnancy and breastfeeding. It is crucial to consult your doctor before using this medicine if you are pregnant or breastfeeding to discuss the potential risks and benefits.

Can Zoxan Eye Drops be taken with other medications?

Specific drug interaction studies with ophthalmic ciprofloxacin are limited due to its low systemic absorption. However, it's important to inform your doctor about all medications you are currently taking, including over-the-counter drugs and herbal supplements. If you are using other topical ophthalmic medications, they should be administered at least 5 to 15 minutes apart, with eye ointments applied last.

What precautions should be taken while using Zoxan Eye Drops?

• Do not use Zoxan Eye Drops if you are allergic to ciprofloxacin, other quinolone antibiotics, or any other ingredients in the drops.
• Avoid wearing contact lenses during treatment for an eye infection. If you are permitted to wear contact lenses, remove them before applying the drops and wait at least 15 minutes before reinserting them.
• Complete the full prescribed course of treatment, even if your symptoms improve, to ensure the infection is fully eradicated and to prevent the development of antibiotic resistance.
• Zoxan Eye Drops may cause temporary blurred vision. Avoid driving or operating heavy machinery until your vision is clear.
• To prevent contamination, do not touch the tip of the dropper to your eye or any other surface.

What happens if a dose of Zoxan Eye Drops is missed?

If you miss a dose of Zoxan Eye Drops, apply it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not use extra drops to make up for a missed dose.

How should Zoxan Eye Drops be stored?

Store Zoxan Eye Drops at room temperature, typically not exceeding 30°C or below 25°C, and protect them from direct light. Keep the bottle tightly sealed when not in use and ensure it is kept out of reach of children. It is recommended to discard the product 30 days after opening.