Sitanat-dm 1000

SITANAT-DM 1000 is a medication manufactured by NATCO PHARMA LIMITED, designed for the management of Type 2 Diabetes Mellitus.

Name

• Common Name: Sitanat-DM 1000 Tablet
• Brand Name: SITANAT-DM 1000 (by NATCO PHARMA LIMITED)

Composition

SITANAT-DM 1000 contains a triple combination of active ingredients:

• Dapagliflozin (10 mg)
• Sitagliptin (100 mg)
• Metformin (1000 mg), often as Metformin Hydrochloride

Uses

SITANAT-DM 1000 is prescribed for:

• Type 2 Diabetes Management: To improve blood sugar control in adults with Type 2 Diabetes Mellitus, particularly when blood sugar levels are not adequately controlled by metformin alone, and as an adjunct to diet and exercise.
• Cardiovascular and Kidney Protection: It helps lower the risk of heart failure and diabetic kidney disease.
• Weight and Metabolic Control: May support weight loss and improve metabolic health.

Dosage and Administration

• SITANAT-DM 1000 should be taken as advised by your doctor.
• It can be taken with or without food.
• It is recommended to take the tablet at the same time each day for optimal benefits.
• Swallow the tablet whole; do not crush, break, or chew it.
• Do not discontinue the medication without consulting your doctor, as this may increase blood sugar levels and the risk of serious complications.

Side Effects

• Common Side Effects: Vomiting, nausea, abdominal pain, headache, stomach upset, genital fungal infection, nasopharyngitis (inflammation of the throat and nasal passages), and urinary tract infection.
• Serious Side Effects (Seek immediate medical attention if experienced): Signs of lactic acidosis (weakness, breathing difficulty, stomach pain), symptoms of ketoacidosis (nausea, vomiting, confusion, fruity breath), painful or persistent genital or urinary infections, pancreatitis (severe stomach pain or nausea), allergic reactions (rash, swelling, breathing problems), and extremely low blood sugar levels (hypoglycemia).

Precautions

• Medical History: Inform your doctor about your complete medical history, including any existing conditions, and all medications, herbs, or supplements you are taking.
• Contraindications: Not recommended for patients with severe liver or kidney disease, Type 1 diabetes, metabolic acidosis, or diabetic ketoacidosis.
• Children: Not recommended for use in children below 18 years of age.
• Alcohol: Avoid excessive alcohol intake, as it increases the risk of hypoglycemia and lactic acidosis.
• Pregnancy & Breastfeeding: Consult your doctor if you are pregnant or breastfeeding, as information on its effects in these conditions is limited.
• Hydration & Hygiene: Drink plenty of fluids to prevent dehydration. Maintain good personal hygiene to help prevent fungal infections.
• Monitoring: Regular monitoring of blood sugar levels and kidney function is advised.
• Driving: Sitanat-DM 1000 may decrease alertness, affect vision, or cause dizziness, so caution is advised when driving or operating machinery.
• Drug Interactions: Use with caution alongside diuretics, insulin, or insulin secretagogues, as this may increase the risk of low blood pressure or extremely low blood sugar levels.

Storage

• Store in a cool and dry place, away from direct sunlight.
• Keep the medicine out of the sight and reach of children.
• Store at temperatures between 10ºC and 25ºC, or below 30ºC.
• Keep the container or pack tightly closed.

SITANAT-DM 1000 by NATCO PHARMA LIMITED is a medication used to manage Type 2 Diabetes Mellitus. It combines three active ingredients: Dapagliflozin, Sitagliptin, and Metformin, each working through a different mechanism to help control blood sugar levels.

Here are some frequently asked questions about SITANAT-DM 1000:

What is SITANAT-DM 1000 used for?

SITANAT-DM 1000 is an antidiabetic medicine primarily used to treat Type 2 Diabetes Mellitus in adults. It helps improve blood sugar control, especially when diet and exercise alone are not sufficient. Additionally, it may offer cardiovascular and kidney protection by lowering the risk of heart failure and diabetic kidney disease.

How does SITANAT-DM 1000 work?

SITANAT-DM 1000 is a combination of three medicines: Dapagliflozin, Sitagliptin, and Metformin.

• Dapagliflozin works by helping the kidneys remove excess sugar from the body through urine.
• Sitagliptin increases the amounts of certain natural substances (incretins) that lower blood sugar when it is high, and helps the pancreas release more insulin.
• Metformin reduces sugar production by the liver cells, delays sugar absorption from the intestines, and improves the body's sensitivity to insulin.

What is the usual dosage for SITANAT-DM 1000?

SITANAT-DM 1000 should be taken exactly as advised by your doctor. It can typically be taken with or without food, but it is recommended to take it consistently at the same time each day. Do not crush, break, or chew the tablet. Your doctor will determine the appropriate dose and duration of treatment based on your condition.

What are the possible side effects of SITANAT-DM 1000?

Common side effects may include vomiting, nausea, abdominal pain, headache, stomach upset, diarrhea, flatulence, urinary tract infection, nasal congestion, sore throat, and genital fungal infections. Most of these side effects are temporary and do not require medical attention. However, serious side effects, though rare, can occur, such as lactic acidosis (symptoms like weakness, breathing difficulty, or stomach pain), ketoacidosis (nausea, vomiting, confusion, or fruity breath), pancreatitis, or severe allergic reactions. Contact your doctor immediately if you experience any serious or persistent side effects.

Is SITANAT-DM 1000 safe during pregnancy or breastfeeding?

SITANAT-DM 1000 is generally not recommended during pregnancy or breastfeeding. There is limited information on its effects in pregnant women, and it is not known if it passes into human breast milk. If you are pregnant, planning a pregnancy, or breastfeeding, you should inform your doctor before taking this medicine.

Can SITANAT-DM 1000 be taken with other medications?

SITANAT-DM 1000 may interact with certain medications. Inform your doctor about all medicines, including herbal supplements, you are currently taking. Caution is advised when taking it with diuretics (water pills), certain blood pressure medications, steroids, insulin, and sulfonylureas, as these can increase the risk of side effects like low blood sugar or dehydration. Drugs that interfere with kidney function can also increase the risk of lactic acidosis.

What precautions should be taken while using SITANAT-DM 1000?

Inform your doctor about any pre-existing medical conditions, especially kidney or liver problems, urinary tract infections, or heart issues. Avoid excessive alcohol intake while on this medication, as it may increase the risk of hypoglycemia and lactic acidosis. It is not recommended for individuals with Type 1 diabetes, diabetic ketoacidosis, or children under 18 years of age. Regular monitoring of blood sugar levels is crucial.

What happens if a dose of SITANAT-DM 1000 is missed?

If you miss a dose of SITANAT-DM 1000, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one, as this can cause a rapid fall in blood sugar levels.

How should SITANAT-DM 1000 be stored?

SITANAT-DM 1000 should be stored in a cool and dry place, away from direct sunlight. Keep it out of the sight and reach of children. The storage temperature should generally be between 10ºC to 25ºC or below 30ºC.