Xmet Sr 1 Gm Tablet

XMET SR 1 GM TABLET by GLENMARK LABORATORIES

Name

• Brand Name: Xmet-SR
• Common Name: Metformin (as its active ingredient)

Composition

• Active Ingredients: Metformin Hydrochloride 1000 mg

Uses

XMET SR 1 GM Tablet is primarily used for the management of Type 2 Diabetes Mellitus, particularly when diet and exercise alone have not been sufficient to control blood glucose levels. It helps to lower blood sugar by decreasing glucose production in the liver, delaying glucose absorption from the intestines, and improving the body's sensitivity to insulin.

Additionally, it is prescribed for the treatment of Polycystic Ovary Syndrome (PCOS) in women, where it helps in restoring hormonal balance, regulating menstrual cycles, and reducing symptoms like acne and excess hair growth by improving insulin sensitivity. This medication also helps to prevent serious complications associated with diabetes, such as kidney damage, eye damage, nerve problems, heart attack, and stroke.

Dosage and Administration

XMET SR 1 GM Tablet should be taken orally as directed by a healthcare professional. It is generally advised to take the tablet with or after food to minimize gastrointestinal side effects like nausea and abdominal pain. The tablet should be swallowed whole with a glass of water and not be crushed or chewed. For optimal results, it is recommended to take the medicine regularly at the same time each day. Do not exceed the prescribed dosage without consulting a doctor.

Side Effects

Common Side Effects:

• Diarrhea
• Nausea and Vomiting
• Abdominal pain or discomfort
• Loss of appetite
• Bloating and Flatulence
• Indigestion
• Headache
• Metallic taste

Serious Side Effects (Rare):

• Lactic Acidosis: Characterized by deep or rapid breathing, persistent nausea, vomiting, and stomach pain. Seek immediate medical attention if these symptoms occur.
• Vitamin B12 Deficiency: Prolonged use may lead to vitamin B12 deficiency, potentially causing anemia, fatigue, pale skin, shortness of breath, or headache.

Precautions

• Allergies: Do not take if allergic to Metformin or any other components of the tablet.
• Kidney/Liver Impairment: Contraindicated in severe kidney disease and should be used with caution in liver problems.
• Cardiac Conditions: Avoid in patients with uncontrolled diabetes, severe heart failure, or who have recently had a heart attack.
• Alcohol Consumption: Excessive alcohol intake should be avoided as it increases the risk of lactic acidosis and low blood sugar.
• Pregnancy and Breastfeeding: Consult your doctor if pregnant, planning to become pregnant, or breastfeeding.
• Drug Interactions: Inform your doctor about all other medications, supplements, or herbal preparations you are taking, including carbonic anhydrase inhibitors, antianginals, H2 blockers, loop diuretics, and certain pain relievers (e.g., ibuprofen, celecoxib).
• Medical Procedures: Discontinue XMET SR temporarily before or at the time of injection with iodine-containing contrast media for X-rays or scans.
• Hypoglycemia: While XMET SR generally does not cause sudden low blood sugar, it can occur when taken with other antidiabetic medicines or alcohol, or due to delayed/skipped meals. Carry a sugar source for immediate relief.
• Regular Monitoring: Regular monitoring of blood sugar levels and kidney function is essential during treatment.

Storage

Store in a cool and dry place, away from direct sunlight. The recommended storage temperature is typically below 30°C or between 10ºC to 25ºC. Keep out of sight and reach of children.

XMET SR 1 GM TABLET by Glenmark Laboratories is a medication primarily used to manage type 2 diabetes mellitus. It contains Metformin (1000mg) as its active ingredient.

Here are some frequently asked questions about XMET SR 1 GM TABLET:

What is XMET SR 1 GM Tablet used for?

XMET SR 1 GM Tablet is primarily used to control high blood sugar levels in individuals with type 2 diabetes mellitus, especially when diet and exercise alone are not sufficient. It is also used off-label to treat Polycystic Ovary Syndrome (PCOS) in women, helping to restore hormonal balance, regulate menstruation, and lower blood sugar levels in affected individuals.

How does XMET SR 1 GM Tablet work?

XMET SR 1 GM Tablet contains Metformin, which works in several ways to lower blood sugar. It decreases the amount of glucose produced by the liver, slows down the absorption of glucose from the intestines into the bloodstream, and increases the body's sensitivity to insulin, allowing cells to use glucose more effectively. In PCOS, it improves insulin sensitivity, which helps lower insulin and androgen levels, thereby restoring ovulation and menstrual regularity.

What is the usual dosage for XMET SR 1 GM Tablet?

The dosage of XMET SR 1 GM Tablet is prescribed by your doctor and can vary based on the severity of your condition and your response to the medicine. It is crucial not to exceed the prescribed dosage. Typically, it is taken once or twice daily, often with meals to minimize gastrointestinal side effects. It should be swallowed whole and not chewed, crushed, or broken.

What are the possible side effects of XMET SR 1 GM Tablet?

Common side effects include diarrhea, nausea, vomiting, abdominal pain, bloating, flatulence, indigestion, headache, and a metallic taste in the mouth. These side effects are usually temporary and may resolve as your body adjusts to the medication. In rare cases, a serious condition called lactic acidosis can occur, especially in individuals with kidney problems, heart failure, or those consuming excessive alcohol. Symptoms of lactic acidosis include muscle pain, stomach pain, vomiting, difficulty breathing, and low body temperature. Prolonged use may also lead to vitamin B12 deficiency.

Is XMET SR 1 GM Tablet safe during pregnancy or breastfeeding?

Caution is advised during pregnancy. XMET SR 1 GM Tablet can be taken during pregnancy if prescribed by your doctor. If you are breastfeeding, metformin is known to pass into breast milk, but the amount is generally considered low enough to not cause significant side effects in the infant. However, it should only be used if prescribed by your doctor.

Can XMET SR 1 GM Tablet be taken with other medications?

XMET SR 1 GM Tablet can interact with certain medications. Inform your doctor about all medicines, supplements, or herbal preparations you are taking. Some medications that may interact include carbonic anhydrase inhibitors (e.g., topiramate), antianginals (e.g., ranolazine), H2 blockers (e.g., cimetidine), loop diuretics (e.g., furosemide), and corticosteroids (e.g., prednisone). It's important to consult your doctor before taking blood pressure medications or insulin with XMET SR.

What precautions should be taken with XMET SR 1 GM Tablet?

Inform your doctor if you have kidney, liver, or heart problems, severe infections, or are severely dehydrated. Avoid excessive alcohol consumption, as it can increase the risk of lactic acidosis and low blood sugar. Monitor your blood sugar levels regularly, especially if taking other antidiabetic medications. If you experience symptoms of low blood sugar (hypoglycemia) like dizziness or weakness, consume a sugary snack or drink.

What happens if a dose is missed?

If you miss a dose of XMET SR 1 GM Tablet, take it as soon as you remember. However, if it's almost time for your next dose, skip the missed one and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should XMET SR 1 GM Tablet be stored?

Store XMET SR 1 GM Tablet at room temperature in a tightly closed container, protected from direct sunlight, excessive heat, and moisture. Keep it out of the reach of children. Always use the medicine before its expiration date.