Lipirose F 10 Mg Tablet (10 Tab)

LIPIROSE F 10 MG TABLET

Name

• Brand Name: Lipirose F 10 mg Tablet
• Manufacturer: Mankind Pharma Ltd.

Composition Lipirose F 10 mg Tablet contains a combination of two active ingredients:

• Rosuvastatin (10 mg)
• Fenofibrate (145 mg)

Uses This medication is primarily used for the management of abnormal lipid/cholesterol levels in the blood. It is prescribed for:

• Lowering elevated levels of total cholesterol and triglycerides.
• Reducing high triglyceride levels in the blood, which helps prevent pancreatitis.
• Prevention of heart attacks, strokes, and cardiovascular diseases.
• Treatment of hyperlipidemia (high lipid levels), mixed dyslipidemia, hypercholesterolemia (high cholesterol), and hypertriglyceridemia (high triglyceride levels).
• Slowing the progression of atherosclerosis.

Dosage and Administration Lipirose F 10 mg Tablet is typically taken orally once daily, with or without food. It should be swallowed whole and not crushed, chewed, or broken. The dosage is determined by a healthcare professional based on the patient's cholesterol levels and response to the medication. Consistency in taking the medication at the same time each day is recommended.

Side Effects Common side effects may include:

• Headache
• Muscle pain (myalgia)
• Constipation
• Nausea
• Abdominal pain
• Weakness
• Joint pain
• Abnormal liver function tests
• Elevated creatine kinase levels
• New-onset diabetes

Serious side effects can include liver damage, myopathy, and rhabdomyolysis, which can affect the kidneys.

Precautions

• Allergies: Do not take if allergic to fenofibrate, rosuvastatin, or any other ingredients.
• Liver Disease: Not recommended for individuals with severe liver disease or active liver disease. Caution is advised, and liver function should be monitored.
• Kidney Disease: Not recommended for use in severe kidney impairment due to potential for exacerbation.
• Pregnancy & Breastfeeding: Rosuvastatin is a pregnancy category X medicine and can harm the unborn baby, thus it is considered unsafe during pregnancy. It is also not recommended during breastfeeding as it may pass into breast milk.
• Alcohol: Avoid consuming alcohol as it can increase the risk of liver damage.
• Muscle Disorders: Exercise caution if there is a history of muscle disorders due to the potential for muscle pain and weakness.
• Gallbladder Disease: Not recommended for those with gallbladder conditions like gallstones, as it may increase the risk of gallstones.
• Drug Interactions: Inform your doctor about all medications, including supplements, as interactions can occur with cyclosporine, gemfibrozil, oral anticoagulants (e.g., warfarin), and antacids containing magnesium or aluminum hydroxide.
• Dietary Interactions: Avoid consuming grapefruit or grapefruit juice.
• Monitoring: Regular monitoring of lipid levels, liver function, and kidney function is essential during treatment.
• Lifestyle: This medication should be used as part of a comprehensive lipid management program that includes a healthy diet, regular exercise, weight control, and smoking cessation.

Storage Store Lipirose F 10 mg Tablet in cool and dry conditions, ideally at a temperature below 30°C. Keep the medicine protected from direct heat, light, and moisture to maintain its effectiveness. Ensure it is out of reach of children.

Here are frequently asked questions about LIPIROSE F 10 MG TABLET:

What is LIPIROSE F 10 MG TABLET used for?

LIPIROSE F 10 MG TABLET is primarily used to manage high cholesterol and triglyceride levels in the blood. It helps reduce "bad" cholesterol (LDL) and triglycerides while increasing "good" cholesterol (HDL). This medication is prescribed to reduce the risk of cardiovascular diseases, including heart attacks and strokes, especially when diet and exercise alone are not sufficient.

How does LIPIROSE F 10 MG TABLET work?

This medicine contains two active ingredients: Rosuvastatin (10 mg) and Fenofibrate (145 mg). Rosuvastatin, a statin, works by blocking an enzyme in the liver that is essential for cholesterol production, thereby lowering LDL and total cholesterol. Fenofibrate, a fibric acid derivative, works by increasing the breakdown of triglycerides and enhancing the production of HDL cholesterol. Together, these ingredients work to improve your overall lipid profile.

What is the usual dosage for LIPIROSE F 10 MG TABLET?

The typical starting dose is one 10mg tablet once daily. Your doctor will determine the appropriate dosage based on your cholesterol levels and how you respond to the medication. It should be taken orally, with or without food, preferably at the same time each day for maximum effectiveness. The tablet should be swallowed whole and not crushed, chewed, or broken. Always follow your doctor's prescribed dosage and do not increase it without consultation.

What are the possible side effects of LIPIROSE F 10 MG TABLET?

Common side effects can include headache, muscle pain, constipation, nausea, abdominal pain, joint pain, and elevated liver enzyme levels. Most of these side effects are usually mild and temporary. If any side effects persist, worsen, or if you experience unusual muscle pain, tenderness, weakness, or dark urine, it is important to contact your doctor immediately.

Is LIPIROSE F 10 MG TABLET safe during pregnancy or breastfeeding?

No, LIPIROSE F 10 MG TABLET is considered unsafe and is not recommended during pregnancy as it may cause harm to the unborn baby. Women of childbearing potential should use effective contraception while taking this medication. It is also not recommended for use during breastfeeding, as its components may pass into breast milk and affect the baby.

Can LIPIROSE F 10 MG TABLET be taken with other medications?

LIPIROSE F 10 MG TABLET can interact with several other medications. It may increase the risk of bleeding when taken with blood thinners like warfarin. Concurrent use with cyclosporine can increase the risk of kidney damage. Taking it with other cholesterol-lowering medicines (like gemfibrozil or other statins) or fusidic acid can increase the chance of muscle disorders. Oral contraceptives containing estrogen may also interact with this medicine. Always inform your doctor about all prescription, over-the-counter, and herbal medications you are currently taking to avoid potential interactions.

What precautions should be taken while using LIPIROSE F 10 MG TABLET?

You should not take LIPIROSE F 10 MG TABLET if you are allergic to rosuvastatin or fenofibrate, or if you have severe kidney or liver disease, active liver disease, or gallbladder conditions (such as gallstones). Use with caution if you have diabetes, hypothyroidism, or a history of muscle disorders. Alcohol consumption should be avoided as it can increase the risk of liver damage. Regular monitoring of liver function and lipid levels by your doctor is important. Do not stop taking the medicine without consulting your doctor, and continue to follow a healthy diet and exercise regimen.

What happens if a dose of LIPIROSE F 10 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should LIPIROSE F 10 MG TABLET be stored?

Store LIPIROSE F 10 MG TABLET in a cool and dry place, ideally below 30°C. Keep it protected from direct heat, light, and moisture. Ensure the medicine is kept out of reach of children.