Dibizide M Tablet (10 Tab)

DIBIZIDE M TABLET (10 TAB) by MICRO LABS LIMITED

Name: Dibizide M Tablet

Composition: Dibizide M Tablet contains a combination of two active ingredients: Glipizide (5 mg) and Metformin (500 mg). Glipizide belongs to the sulfonylurea class, stimulating insulin release from the pancreas and reducing glucose output from the liver. Metformin, a biguanide, works by decreasing glucose production in the liver, delaying glucose absorption from the intestines, and improving the body's sensitivity to insulin.

Uses: This medication is primarily prescribed for adults with Type 2 Diabetes Mellitus to manage high blood sugar levels. It is used when diet, exercise, and treatment with a single antidiabetic agent are not sufficient for adequate blood sugar control. By effectively managing diabetes, it helps reduce the risk of associated complications such as kidney damage, eye damage, nerve problems, and cardiovascular diseases.

Dosage and Administration: Dibizide M Tablet is typically taken orally with food, usually once or twice daily, at the same time each day to maximize its benefits and minimize gastrointestinal side effects. The exact dosage and duration of treatment are determined by a physician based on the patient's individual condition and response to treatment. Do not crush, break, or chew the tablet; swallow it whole with a glass of water.

Side Effects: Common side effects may include low blood sugar (hypoglycemia), nausea, stomach upset, diarrhea, headache, dizziness, and changes in taste. Hypoglycemia can manifest as shakiness, weakness, sweating, and blurred vision. More serious, though rare, side effects can include lactic acidosis, particularly in individuals with kidney, liver, or heart diseases, and signs of liver problems.

Precautions:

• Allergies: Do not take if allergic to glipizide, metformin, or any other ingredients in the tablet.
• Pregnancy and Breastfeeding: Not recommended for use during pregnancy or breastfeeding.
• Alcohol: Avoid alcohol consumption as it can increase the risk of low blood sugar and lactic acidosis.
• Medical Conditions: Inform your doctor if you have kidney, liver, or heart problems, severe heart failure, metabolic acidosis, diabetic ketoacidosis, or a deficiency of glucose-6-phosphate dehydrogenase (G6PD).
• Driving and Machinery: May cause dizziness or drowsiness; avoid driving or operating machinery until you know how the medicine affects you.
• Drug Interactions: Exercise caution with concomitant use of miconazole, danazol, phenylbutazone, certain diuretics, medicines for pain and inflammation, and some asthma medications, as they can interact with Dibizide M.
• Vitamin B12: Dibizide M may interfere with Vitamin B12 absorption, potentially leading to anemia.

Storage: Store Dibizide M Tablet in a cool, dry place, protected from moisture and heat, and away from direct sunlight. Keep out of sight and reach of children and pets. Do not use expired or damaged medicines.

What is Dibizide M Tablet used for?

Dibizide M Tablet is primarily used to manage type 2 diabetes mellitus in adults. It helps control high blood sugar levels when diet, exercise, and treatment with single medications are not sufficient. By effectively managing diabetes, it can help reduce the risk of associated complications such as kidney damage, eye damage, nerve problems, and cardiovascular diseases.

How does Dibizide M Tablet work?

Dibizide M Tablet contains two active ingredients: Glipizide and Metformin.

• Glipizide is a sulfonylurea that works by stimulating the pancreas to release more insulin, a hormone that helps lower blood glucose levels.
• Metformin is a biguanide that reduces glucose production in the liver, delays glucose absorption from the intestines, and improves the body's sensitivity to insulin. This dual action helps in more effective blood sugar control.

What is the usual dosage for Dibizide M Tablet?

The dosage of Dibizide M Tablet can vary depending on individual patient needs, blood glucose levels, and response to treatment. It is typically administered orally with food, usually once or twice daily, at the same time each day for the best benefit and to maintain consistent blood glucose levels. It is crucial to follow your doctor's instructions carefully and not exceed the prescribed dose.

What are the possible side effects of Dibizide M Tablet?

Common side effects of Dibizide M Tablet may include low blood sugar (hypoglycemia), nausea, vomiting, diarrhea, stomach upset, headache, dizziness, and altered taste. Low blood sugar can manifest as shakiness, weakness, dizziness, and hunger. More serious but rare side effects include lactic acidosis, especially in older patients or those with kidney, liver, or heart diseases. Long-term use may also lead to Vitamin B12 deficiency. If you experience any persistent or severe side effects, or signs of lactic acidosis (e.g., cold hands or feet, unusual muscle pain, trouble breathing), consult your doctor immediately.

Is Dibizide M Tablet safe during pregnancy or breastfeeding?

Dibizide M Tablet is generally not recommended for use during pregnancy as it may harm the unborn baby. For pregnancy-related diabetes, insulin is often preferred over oral blood sugar-lowering medicines. Regarding breastfeeding, limited information is available, and Dibizide M Tablet should generally not be used while breastfeeding. Always consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding before taking this medicine.

Can Dibizide M Tablet be taken with other medications?

Dibizide M Tablet can interact with various medications, potentially altering the treatment response or increasing the risk of side effects.

• It should not be used with miconazole (for fungal infections) as it can cause very low blood sugar.
• Combining it with danazol (for breast and menstrual disorders) may cause high blood sugar.
• Caution is advised when taken with other antidiabetic drugs (e.g., insulin), certain antibiotics (like ciprofloxacin), pain and inflammation medicines (e.g., ibuprofen), blood pressure medications (e.g., captopril), and some asthma medications (e.g., salbutamol). Always inform your doctor about all medicines, including prescription, over-the-counter drugs, and herbal supplements you are taking, to avoid potential interactions.

What precautions should be taken while using Dibizide M Tablet?

Several precautions should be taken:

• Alcohol: Avoid alcohol consumption as it can increase the risk of low blood sugar and a serious condition called lactic acidosis.
• Medical Conditions: Inform your doctor if you have a history of heart disease, kidney or liver problems, type 1 diabetes, severe infections, or dehydration.
• Driving & Machinery: This medicine may cause dizziness or drowsiness, or low blood sugar, which can affect your ability to drive or operate machinery. Exercise caution until you know how the medicine affects you.
• Allergies: Do not take Dibizide M Tablet if you are allergic to glipizide, metformin, or any other ingredients.
• Monitoring: Regular monitoring of blood sugar levels is essential to assess the effectiveness and adjust the dosage as needed.

What happens if a dose of Dibizide M Tablet is missed?

If you forget to take a dose of Dibizide M Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this can increase the risk of side effects.

How should Dibizide M Tablet be stored?

Dibizide M Tablet should be stored in a cool, dry place, protected from moisture and heat. Keep it out of reach and sight of children and pets. Do not use expired or damaged medicines and dispose of any unused medicine properly.