Doxinate Od Tablet (30 Tab)

DOXINATE OD TABLET (30 TAB) by MANEESH PHARMACEUTICALS LTD.

DOXINATE OD TABLET is a medication primarily used for the management of nausea and vomiting during pregnancy. It is manufactured by Maneesh Pharmaceuticals Ltd.

• Name

  • Brand Name: Doxinate OD Tablet
  • Common Name of Active Ingredients: Doxylamine and Pyridoxine

• Composition Each DOXINATE OD TABLET contains:

  • Doxylamine: 20 mg
  • Pyridoxine (Vitamin B6): 20 mg This is an extended-release or delayed-release tablet formulation.

• Uses DOXINATE OD TABLET is prescribed for:

  • Treating nausea and vomiting in pregnancy, commonly known as "morning sickness."
  • Managing severe forms of pregnancy-related nausea and vomiting, such as hyperemesis gravidarum.
  • Providing nutritional support, as Pyridoxine (Vitamin B6) helps address deficiencies that may contribute to nausea and supports fetal brain development and immune system.

• Dosage and Administration

  • Take DOXINATE OD TABLET exactly as prescribed by your doctor.
  • It is typically taken once daily at bedtime. If symptoms persist, your doctor may recommend taking it 1 tablet in the morning and 1 tablet at bedtime, not exceeding two tablets per day.
  • The tablet should be swallowed whole with a glass of water on an empty stomach, ideally at least 1 hour before or 2 hours after a meal. Do not chew, crush, or break the tablet.
  • Do not exceed the recommended dose or discontinue the medicine suddenly without consulting your doctor.

• Side Effects Common side effects may include:

  • Drowsiness, dizziness, lightheadedness
  • Dry mouth
  • Constipation, stomach pain, diarrhea
  • Headache, restlessness, blurred vision Serious side effects requiring immediate medical attention are rare but can include allergic reactions (rash, itching, swelling, difficulty breathing), severe drowsiness, sudden eye pain, or trouble passing urine.

• Precautions

  • Alcohol: Avoid consuming alcohol, as it can increase dizziness and drowsiness.
  • Driving/Operating Machinery: Due to potential drowsiness and dizziness, exercise caution when driving or operating heavy machinery until you know how the medicine affects you.
  • Medical Conditions: Inform your doctor about any pre-existing conditions such as asthma, glaucoma, stomach ulcers, gut or urinary bladder blockage, liver, or kidney problems.
  • Drug Interactions: Discuss all other medications you are taking, including antidepressants (especially MAO inhibitors), cough and cold remedies, sleeping aids, and certain pain medicines, as they can interact with Doxinate OD.
  • Breastfeeding: It is generally not recommended for breastfeeding mothers as its components can pass into breast milk. Consult your doctor if you are breastfeeding.
  • Children: The safety and efficacy of Doxinate OD TABLET have not been established for use in children.

• Storage Store DOXINATE OD TABLET in a cool and dry place, protected from direct sunlight, moisture, and heat. Keep it below 25°C or 30°C. Keep this medicine out of the reach and sight of children and pets. Do not use the medicine if the packaging is damaged or tampered with, or if it has passed its expiry date.

DOXINATE OD TABLET (30 TAB) by MANEESH PHARMACEUTICALS LTD. is a medication primarily used to manage nausea and vomiting during pregnancy. It contains a combination of doxylamine succinate and pyridoxine hydrochloride (Vitamin B6).

What is DOXINATE OD TABLET used for?

DOXINATE OD TABLET is primarily used to treat nausea and vomiting associated with pregnancy, commonly known as morning sickness. It is specifically designed to alleviate these uncomfortable symptoms, helping pregnant women manage daily activities. The medicine may also be used to address Vitamin B6 deficiency, which can contribute to nausea and vomiting during pregnancy.

How does DOXINATE OD TABLET work?

This medicine contains two active ingredients: doxylamine succinate and pyridoxine hydrochloride (Vitamin B6). Doxylamine is an antihistamine that works by blocking certain natural substances (histamine) in the body and specific receptors in the brain responsible for triggering nausea and vomiting. Pyridoxine (Vitamin B6) also helps to control these symptoms, possibly by regulating neurotransmitters in the brain, and provides nutritional support. The "OD" in DOXINATE OD often indicates an extended or delayed-release formulation, designed to provide sustained therapeutic benefits.

What is the usual dosage for DOXINATE OD TABLET?

The dosage of DOXINATE OD TABLET should be taken as prescribed by your doctor. Typically, it is taken once daily, usually one tablet at bedtime. Depending on the severity of symptoms, your doctor might recommend taking an additional tablet in the morning or mid-afternoon. It is generally advised to take the tablet on an empty stomach for better absorption, but it can be taken with or without food. Swallow the tablet whole with water; do not chew, crush, or split it. Do not exceed the prescribed dose.

What are the possible side effects of DOXINATE OD TABLET?

Common side effects of DOXINATE OD TABLET include drowsiness or excessive sleepiness, dizziness, dry mouth, constipation, and lightheadedness. Less common side effects may include rashes, itching, blurred vision, stomach pain, muscle pain or weakness, difficulty in urination, confusion, restlessness, and headache. If you experience persistent or concerning side effects, or any signs of a severe allergic reaction (such as rash, itching, swelling, or difficulty breathing), seek immediate medical attention.

Is DOXINATE OD TABLET safe during pregnancy or breastfeeding?

Pregnancy: DOXINATE OD TABLET is specifically designed and considered safe for use during pregnancy to treat nausea and vomiting when prescribed by a doctor. It has been recommended as a first-line treatment for nausea and vomiting in pregnancy by various medical organizations.

Breastfeeding: The use of DOXINATE OD TABLET is generally not recommended while breastfeeding. Doxylamine, one of the active ingredients, can pass into breast milk and may cause sedation, irritability, or other effects in the nursing infant. Always consult your doctor if you are breastfeeding and considering this medication.

Can DOXINATE OD TABLET be taken with other medications?

DOXINATE OD TABLET can interact with other medications, potentially altering their effects. You should exercise caution and inform your doctor if you are taking:

• CNS depressants: Such as alcohol, barbiturates, hypnotics, opioid pain killers, anxiolytic sedatives, or antipsychotics, as these can increase drowsiness and other sedative effects.
• MAO inhibitors: These antidepressants can interact negatively with DOXINATE OD.
• Other antihistamines or sleeping pills: Concurrent use can worsen side effects like drowsiness.
• Levodopa, Phenobarb, or Phenytoin: Pyridoxine in DOXINATE OD can reduce the effects of these medications. Always inform your doctor about all prescription, over-the-counter, and herbal medications you are currently taking.

What precautions should be taken while using DOXINATE OD TABLET?

• Alcohol Consumption: Avoid consuming alcohol while taking DOXINATE OD TABLET, as it can intensify drowsiness and dizziness.
• Driving and Operating Machinery: This medicine can cause dizziness, drowsiness, or blurred vision. Avoid driving or operating heavy machinery until you know how the medication affects you.
• Medical Conditions: Inform your doctor if you have pre-existing medical conditions such as liver disease, kidney problems, asthma, glaucoma (especially narrow-angle glaucoma), stomach ulcers, gut blockage, urinary bladder blockage, prostatic hypertrophy, or epilepsy.
• Discontinuation: Do not stop taking DOXINATE OD TABLET suddenly without consulting your doctor, even if you feel better, as it may lead to a recurrence of symptoms.
• Children: DOXINATE OD TABLET is not recommended for use in children under 18 years of age.

What happens if a dose of DOXINATE OD TABLET is missed?

If you miss a dose of DOXINATE OD TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should DOXINATE OD TABLET be stored?

Store DOXINATE OD TABLET in a clean, dry place below 25°C (or at room temperature), away from moisture, direct sunlight, and heat. Keep the medicine out of reach of children and pets. Do not use the medicine if the packaging is damaged or tampered with, or if it has passed its expiry date. Dispose of expired or no longer needed medicine properly.