Brivasure 25mg Tab

BRIVASURE 25MG TABLET

BRIVASURE 25MG Tablet, manufactured by Alkem Laboratories Ltd, is an anti-epileptic medication primarily used in the management of seizures.

• Name:

  • Brand Name: Brivasure 25MG Tablet
  • Common Name: Brivaracetam (active ingredient)

• Composition:

  • Each tablet contains Brivaracetam 25 mg.

• Uses: BRIVASURE 25MG Tablet is prescribed for the treatment of epilepsy and other seizure disorders. It is specifically used to manage partial-onset seizures (also known as focal seizures), which involve abnormal electrical activity in one part of the brain. It can be used alone (monotherapy) or in combination with other anti-epileptic drugs (adjunctive therapy) in adults and children aged 1 month and older. The medication works by stabilizing electrical activity in the brain and preventing abnormal nerve activity to reduce the frequency and intensity of seizures.

• Dosage and Administration:

  • Take BRIVASURE 25MG Tablet exactly as advised by your physician.
  • Swallow the tablet whole with a glass of water; do not crush or chew it.
  • It can be taken with or without food.
  • For optimal benefit, it is recommended to take the medicine at the same time each day.
  • The doctor will determine the correct dose and duration based on the patient's age, body weight, and medical condition, and the dosage may be adjusted gradually.
  • BRIVASURE 25MG Tablet is typically prescribed for long-term treatment. Do not stop or miss doses suddenly, as this can worsen seizures.
  • For adults and children 16 years and older, a typical starting dose may be 50 milligrams (mg) twice a day, with a maximum of 100 mg twice a day. For children younger than 16 years, the dosage is weight-based and determined by a doctor.

• Side Effects:

  • Common Side Effects: Sleepiness or dizziness, fatigue (feeling very tired), nausea, vomiting, headache, irritability, flu-like symptoms, constipation, anxiety, insomnia (not being able to sleep), infections of the nose and throat, cough, decreased appetite, and psychomotor hyperactivity (restlessness, agitation).
  • Serious Side Effects (less common): Depression, self-harming thoughts, unusual mood and behavioral changes (e.g., aggression, agitation), severe allergic reactions (such as rash, itching, difficulty breathing), and an increase or worsening of seizures.

• Precautions:

  • Pregnancy and Breastfeeding: Not recommended for use during pregnancy unless absolutely necessary and only under strict medical supervision. It is also not recommended for breastfeeding women as it may pass into breast milk.
  • Alcohol: Avoid alcohol consumption while taking this medication, as it can increase side effects like dizziness and difficulty concentrating.
  • Driving and Operating Machinery: Patients should not drive or operate heavy machinery if they experience sleepiness, dizziness, or tiredness while on this medication.
  • Liver and Kidney Issues: Inform your doctor if you have liver or kidney problems, as dose adjustments may be necessary. It is not recommended for patients with severe liver problems or end-stage renal disease undergoing dialysis.
  • Mental Health: Patients with a history of depression, self-harming thoughts, or unusual changes in mood and behavior should inform their doctor, as close monitoring may be required.
  • Pediatric Use: While some sources indicate use for children as young as 1 month, others state it is not recommended for children under 4 years of age. Always follow your doctor's specific guidance.
  • Discontinuation: Do not discontinue BRIVASURE 25MG Tablet abruptly, as this can lead to an increase in seizure frequency or severity. Gradual discontinuation under medical supervision is advised.
  • Overdosage: Symptoms of overdose may include dizziness, excessive sleepiness, feeling sick, a spinning sensation (vertigo), problems with balance, anxiety, extreme tiredness, irritability, aggression, insomnia, or self-harming thoughts. Seek immediate medical attention if an overdose is suspected.

• Storage:

  • Store in a cool and dry place, away from direct sunlight.
  • Keep out of the sight and reach of children and pets.
  • Do not store above 25°C.

BRIVASURE 25MG TAB contains the active ingredient Brivaracetam, an anticonvulsant medication used to treat epilepsy.

Here are some frequently asked questions about BRIVASURE 25MG TAB:

What is BRIVASURE 25MG TAB used for?

BRIVASURE 25MG TAB is used to help control partial-onset seizures (also known as focal seizures) in individuals with epilepsy. It can be prescribed either alone or in combination with other anti-epileptic medications.

How does BRIVASURE 25MG TAB work?

The active ingredient, Brivaracetam, works by binding to a specific protein in the brain called synaptic vesicle glycoprotein 2A (SV2A). This action helps to stabilize electrical activity in the brain and prevents the abnormal firing of nerve cells that can lead to seizures. It may also inhibit sodium channels, contributing to its antiepileptic effect.

What is the usual dosage of BRIVASURE 25MG TAB?

For adults and children 16 years of age and older, the typical starting dose is 50 milligrams (mg) twice a day. The doctor may adjust the dose as needed and tolerated, but it is usually not more than 100 mg twice a day. For children aged 1 month to less than 16 years, the dosage is determined by a doctor and is based on body weight. BRIVASURE tablets should be swallowed whole with liquid and can be taken with or without food, preferably around the same times every day.

What are the possible side effects of BRIVASURE 25MG TAB?

Common side effects include drowsiness (somnolence), dizziness, fatigue, and nausea or vomiting. More serious side effects can include changes in mood or behavior, such as depression, anxiety, agitation, aggression, irritability, or thoughts of self-harm. Other serious effects can include problems with coordination and rare allergic reactions like swelling of the face, throat, or difficulty breathing.

Is BRIVASURE 25MG TAB safe during pregnancy or breastfeeding?

Pregnancy: BRIVASURE (Brivaracetam) is listed in Pregnancy Category C, meaning caution is advised. Animal studies have shown possible harmful effects to the developing fetus, but the benefits for the mother may outweigh the potential risks. It is not known if BRIVASURE will harm an unborn baby. If you are pregnant or planning to become pregnant, discuss this with your healthcare provider, and you may consider enrolling in a pregnancy registry for antiepileptic medications. Breastfeeding: It is not known whether Brivaracetam passes into human breast milk or what effects it might have on a breastfed infant, though animal studies have shown its excretion in milk. If breastfeeding while taking BRIVASURE, your healthcare provider will weigh the benefits and risks, and you should monitor the infant for drowsiness, agitation, adequate weight gain, and developmental milestones.

Can BRIVASURE 25MG TAB be taken with other medications?

BRIVASURE generally has few clinically relevant drug-drug interactions. However, co-administration with carbamazepine may increase levels of carbamazepine-epoxide, and it may also increase phenytoin levels. Alcohol use is not recommended while taking BRIVASURE, as it can worsen psychomotor function and increase sedation. Additionally, caution should be exercised when taking BRIVASURE with other medications that can cause sedation. Taking BRIVASURE with levetiracetam, another anti-epileptic drug, offers no added therapeutic benefit and may cause additive side effects.

What precautions should be taken while using BRIVASURE 25MG TAB?

It is very important not to stop taking BRIVASURE suddenly, as this can lead to an increase in seizure frequency or severity. You should report any new or worsening changes in mood or behavior, including suicidal thoughts, to your doctor immediately. Due to potential dizziness, drowsiness, or coordination problems, avoid driving or operating machinery until you understand how this medication affects you. If you have liver problems, your doctor may need to adjust your dose.

What happens if a dose of BRIVASURE 25MG TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. If you are unsure, contact your healthcare provider for advice.

How should BRIVASURE 25MG TAB be stored?

BRIVASURE tablets should be stored in a closed container at room temperature, away from excessive heat, moisture, and direct light. The oral solution form should not be frozen, and any unused oral solution should be discarded 5 months after first opening the bottle. Keep all medications out of the reach of children.