Looz Solution 500 Ml

LOOZ SOLUTION 500 ML

LOOZ SOLUTION is a widely used laxative manufactured by Intas Pharmaceuticals Ltd..

• Name:

  • Brand Name: LOOZ SOLUTION
  • Common Name: Lactulose Oral Solution

• Composition: LOOZ SOLUTION contains Lactulose (10,000 mg per 15 ml) as its active ingredient.

• Uses: LOOZ SOLUTION is primarily prescribed for the following conditions:

  • Constipation: It is an osmotic laxative that softens stools by drawing water into the bowel, making them easier to pass and promoting regular bowel movements.
  • Hepatic Encephalopathy: It helps manage this serious liver condition by lowering elevated ammonia levels in the blood, which can improve brain function and reduce symptoms like confusion and tremors.
  • Intestine Preparation: It may also be used to prepare the intestines before surgical procedures or medical examinations.

• Dosage and Administration: This medicine should be taken as advised by a doctor, with or without food, preferably at the same time each day for maximum benefit. It can be mixed with fruit juice or water.

  • For Constipation (Adults): A typical starting dose is 15-45 ml per day, with a maintenance dose of 15-30 ml per day.
  • For Hepatic Encephalopathy (Adults): The starting dose is usually 30-45 ml, 3-4 times a day, adjusted to produce 2-3 soft stools per day.
  • For Children: Dosage varies by age (e.g., 1-6 years: 5-10 ml/day; 7-14 years: 10-15 ml/day), as prescribed by a doctor.
  • It generally takes at least 48 hours to show effect for constipation.

• Side Effects: Common side effects include:

  • Diarrhea
  • Flatulence (gas)
  • Abdominal pain and cramps
  • Nausea and Vomiting Serious, though uncommon, side effects can include electrolyte imbalance, especially with high doses or prolonged use.

• Precautions:

  • Do not take if allergic to lactulose or other ingredients.
  • Contraindicated in patients with galactosemia (inability to process galactose), intestinal obstruction, or digestive perforation.
  • Use with caution in patients with diabetes, lactose intolerance, or inflammatory bowel disease.
  • Pregnant and breastfeeding women should use it only if clearly advised by a doctor.
  • Avoid taking other laxatives simultaneously unless directed by a doctor.
  • Inform your doctor about all current medications, as it may interact with certain diuretics, steroids, antifungals, or cardiac glycosides.
  • Drink plenty of fluids (6-8 glasses) daily during treatment.

• Storage: Store LOOZ SOLUTION in a cool, dry place, protected from direct sunlight, moisture, and heat, at a temperature not exceeding 30°C. Keep out of reach of children. Do not refrigerate or freeze. Discard any unused diluted solution after 24 hours.

What is LOOZ SOLUTION used for?

LOOZ SOLUTION, which contains lactulose as its active ingredient, is primarily used to treat constipation by increasing the frequency of bowel movements and softening hard stools. It is also used to manage hepatic encephalopathy, a brain condition resulting from severe liver disease that can cause symptoms like confusion, tremors, and a decreased level of consciousness, by helping to reduce ammonia levels in the blood.

How does LOOZ SOLUTION work?

Lactulose is a synthetic sugar that acts as an osmotic laxative. For constipation, it works by breaking down in the large intestine and drawing water into the bowel, which softens the stool and makes it easier to pass. In cases of hepatic encephalopathy, lactulose helps by drawing ammonia from the blood into the large intestine, where it is then eliminated from the body, thereby reducing harmful ammonia levels. It may take 24 to 48 hours for the laxative effect to be noticeable.

What is the usual dosage for LOOZ SOLUTION?

The dosage of LOOZ SOLUTION varies depending on the condition being treated and individual needs.

• For constipation (adults): The typical starting dose is 15-30 mL (1-2 tablespoons) once daily. This can be increased to a maximum of 60 mL per day if necessary.
• For hepatic encephalopathy (adults): The usual starting dose is 30-45 mL (2-3 tablespoons) three or four times per day. Your doctor will adjust this dose to ensure you have 2-3 soft stools daily. For children, the appropriate dosage must be determined and carefully supervised by a doctor.

What are the possible side effects of LOOZ SOLUTION?

Common side effects can include diarrhea (especially with higher doses), flatulence (gas), nausea, vomiting, abdominal pain, stomach cramping, and bloating. More serious, though rare, side effects that require immediate medical attention include severe diarrhea or vomiting that leads to dehydration and electrolyte imbalance (symptoms like muscle cramps, weakness, or an irregular heartbeat), or signs of an allergic reaction such as a rash, itching, hives, or swelling of the face, lips, tongue, or throat.

Is LOOZ SOLUTION safe during pregnancy or breastfeeding?

LOOZ SOLUTION can generally be used during pregnancy if clearly needed, as it is considered safe and not harmful to the baby. It is also considered acceptable to take lactulose while breastfeeding, as it is unlikely to pass into breast milk or cause side effects in the nursing infant. However, it is always best to consult your doctor or midwife before taking any medication during pregnancy or breastfeeding.

Can LOOZ SOLUTION be taken with other medications?

It is important to inform your doctor about all prescription and non-prescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. LOOZ SOLUTION may interact with certain medications, including antacids, the antibiotic neomycin, and other laxatives. Other drugs that may interact include those used for fluid retention (e.g., chlorthalidone, hydrochlorothiazide), inflammatory conditions (e.g., hydrocortisone, prednisolone), amphotericin B, digitalis, digoxin, and 5-aminosalicylic acid (5-ASA). Avoiding concomitant use of other laxatives is generally recommended.

What precautions should be taken when using LOOZ SOLUTION?

Do not take LOOZ SOLUTION if you have an allergy to lactulose or any of its ingredients, have galactosaemia (a rare problem where you cannot digest milk sugar), an intestinal obstruction, inflammatory bowel disease (such as Crohn's disease or ulcerative colitis), gastrointestinal perforation, or unexplained abdominal pain. Patients with diabetes should use this medicine with caution as it contains sugars (galactose, lactose, and fructose). If you are being treated for hepatic encephalopathy with high doses, your doctor may need to adjust your anti-diabetic medication. It is crucial to drink plenty of fluids (approximately 2 liters/day or 6-8 glasses) while taking lactulose to prevent dehydration. If your condition does not improve after several days or if your symptoms worsen, contact your doctor. Long-term use without medical supervision is not advised.

What happens if a dose of LOOZ SOLUTION is missed?

If you miss a dose of LOOZ SOLUTION, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a forgotten dose.

How should LOOZ SOLUTION be stored?

LOOZ SOLUTION should be stored at room temperature, typically between 15°C and 30°C (59°F and 86°F). Keep the container tightly closed, away from excess heat, moisture, and direct light. Do not freeze the medication, as freezing temperatures may cause it to become semi-solid and too thick to pour. A normal darkening of the solution's color may occur due to its sugar content, which does not affect its therapeutic action. However, if the solution becomes extremely dark or cloudy, it should not be used. Always keep this medicine out of the reach of children and pets.