Torpanel 4mg Tab

TORPANEL 4MG Tablet

TORPANEL 4MG Tablet, manufactured by Torrent Pharmaceuticals Ltd, is an antiepileptic medication used in the management of seizures.

Composition

The active ingredient in TORPANEL 4MG Tablet is Perampanel 4mg.

Uses

TORPANEL 4MG Tablet is prescribed for the treatment of epilepsy, specifically as an adjunctive therapy for:

• Partial-onset seizures with or without secondarily generalized seizures in patients aged 4 years and older.
• Primary generalized tonic-clonic seizures in patients aged 7 years and older. It works by blocking glutamate receptors in the brain, thereby suppressing abnormal and excessive nerve cell activity that leads to seizures.

Dosage and Administration

TORPANEL 4MG Tablet should be taken orally once daily, preferably at bedtime, with or without food. The tablet should be swallowed whole and not chewed, crushed, or broken. Adhere strictly to your doctor's prescribed dosage and treatment duration. Abruptly discontinuing the medication without consulting a doctor can lead to withdrawal symptoms and an increase in seizure frequency.

Side Effects

Common side effects include:

• Dizziness, drowsiness, and fatigue.
• Nausea, weight gain, and changes in appetite.
• Irritability, anger, aggression, and confusion.
• Balance issues, impaired coordination, altered walking, and vertigo.

Serious side effects can include psychiatric and behavioral changes such as aggression, hostility, and suicidal thoughts. Promptly inform your doctor if any unusual mood or behavioral changes occur.

Precautions

• Alcohol: Avoid alcohol consumption as it can increase the risk of seizures and exacerbate side effects like drowsiness and dizziness.
• Driving & Machinery: This medicine may cause dizziness and drowsiness; therefore, avoid driving or operating heavy machinery until you understand how it affects you.
• Pregnancy & Breastfeeding: TORPANEL 4MG Tablet is generally not recommended during pregnancy or breastfeeding. Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
• Pre-existing Conditions: Inform your doctor if you have kidney or liver problems, a history of depression, suicidal ideation, or substance abuse.
• Discontinuation: Do not stop taking this medicine suddenly without consulting your doctor, as it can lead to increased seizure frequency and withdrawal symptoms.

Storage

Keep TORPANEL 4MG Tablet out of the sight and reach of children. Store at room temperature, in a cool and dry place away from direct sunlight.

Frequently Asked Questions (FAQs) About TORPANEL 4MG TAB

TORPANEL 4MG TAB, containing Perampanel, is an antiepileptic medication used to manage certain types of seizures in individuals with epilepsy. Here are some frequently asked questions about this medicine:

What is TORPANEL 4MG TAB used for?

TORPANEL 4MG TAB is primarily used to treat epilepsy, specifically for partial-onset seizures (with or without secondary generalization) and primary generalized tonic-clonic seizures. It is approved for use in patients aged 12 years and older, and in some cases, children aged 4 to 11 years as an add-on therapy.

How does TORPANEL 4MG TAB work?

The active ingredient, Perampanel, works by blocking a specific type of receptor in the brain known as the glutamate receptor. By doing so, it helps to suppress the abnormal and excessive activity of nerve cells in the brain that are responsible for causing seizures.

What is the usual dosage for TORPANEL 4MG TAB?

TORPANEL 4MG TAB is typically taken orally once daily, usually before bedtime, with or without food. It should be swallowed whole and not chewed or crushed. The starting dose is generally 2 mg and may be gradually increased by your doctor. The maximum recommended daily dose is 12 mg. Always follow your doctor's instructions regarding the dose and duration of treatment.

What are the possible side effects of TORPANEL 4MG TAB?

Common side effects can include dizziness, sleepiness or drowsiness, fatigue, anger, falls, nausea, weight gain, vertigo (spinning sensation), impaired coordination, difficulty walking, balance disorders, irritability, headache, increased or decreased appetite, slow speech, blurred vision, double vision, and back pain. More serious psychiatric and behavioral side effects such as aggression, hostility, extreme irritability, and suicidal thoughts can occur. It is important to inform your doctor if you experience any unusual mood changes or signs of depression.

Is TORPANEL 4MG TAB safe during pregnancy or breastfeeding?

Pregnancy: TORPANEL 4MG TAB may be unsafe to use during pregnancy and is generally not recommended for pregnant women or those planning a pregnancy. Women of child-bearing potential should use a reliable method of contraception during treatment and for at least one month after stopping the medication. Consult your doctor if you are pregnant or planning to become pregnant. Breastfeeding: This medication is probably unsafe to use while breastfeeding. Limited data suggests that Perampanel may pass into breast milk and could potentially harm the baby. It is advisable to discuss this with your doctor if you are breastfeeding.

Can TORPANEL 4MG TAB be taken with other medications?

TORPANEL 4MG TAB can interact with other medications. It is crucial to inform your doctor about all medicines you are taking, including over-the-counter drugs, herbal supplements, and vitamins. Notable interactions include:

• Other anti-epileptic medications (e.g., carbamazepine, oxcarbazepine, phenytoin, felbamate, midazolam) may affect its effectiveness.
• Rifampicin (an antibiotic) can decrease its effectiveness.
• Hormonal contraceptives (like estradiol or levonorgestrel) may have reduced effectiveness, and additional non-hormonal contraception is recommended.
• Simultaneous use with other central nervous system (CNS) depressants like diazepam can increase CNS depression.
• St. John's Wort (a herbal medicine) and Ketoconazole (an antifungal) may also interact.

What precautions should be taken while taking TORPANEL 4MG TAB?

• Alcohol: Avoid consuming alcohol as it can increase the risk of seizures and worsen side effects such as drowsiness and dizziness.
• Driving and Machinery: Do not drive or operate heavy machinery until you know how this medicine affects you, as it can cause dizziness and sleepiness.
• Sudden Discontinuation: Do not stop taking TORPANEL 4MG TAB suddenly without consulting your doctor. Abruptly stopping the medication or significantly reducing the dose can increase seizure frequency and lead to withdrawal symptoms like anxiety, nervousness, irritability, fatigue, mood swings, and sleeplessness.
• Pre-existing Conditions: Exercise caution if you have kidney or liver problems, a history of substance abuse, depression, or suicidal thoughts. Inform your doctor about these conditions.
• Children and Elderly: This medicine is not recommended for children below 4 years (for partial seizures) or below 7 years (for generalized seizures). Older patients should use it under medical supervision due to increased susceptibility to side effects.

What happens if a dose of TORPANEL 4MG TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should TORPANEL 4MG TAB be stored?

Store TORPANEL 4MG TAB in its original packaging at room temperature, ideally below 30°C. Keep it out of the reach and sight of children. Protect the medication from moisture and direct light.