Glycinorm Total 30 Mg Tablet (15 Tab)

GLYCINORM TOTAL 30 MG TABLET

GLYCINORM TOTAL 30 MG TABLET, manufactured by Ipca Laboratories Ltd., is an oral antidiabetic medication prescribed for the management of Type 2 Diabetes Mellitus in adults. This combination medicine is utilized when diet, exercise, and single or dual therapy with other agents do not adequately control blood sugar levels.

Composition Each GLYCINORM TOTAL 30 MG TABLET contains a combination of three active ingredients:

• Gliclazide (30 mg)
• Metformin (500 mg)
• Pioglitazone (15 mg)

Uses GLYCINORM TOTAL 30 MG TABLET is primarily used to:

• Treat Type 2 Diabetes Mellitus in adults.
• Improve glycemic control when lifestyle interventions and other medications are insufficient.
• Help prevent long-term complications associated with diabetes, such as kidney damage, nerve problems, blindness, and cardiovascular events.

Dosage and Administration GLYCINORM TOTAL 30 MG TABLET should be taken orally, typically once or twice daily, with food to minimize gastrointestinal side effects. The tablet should be swallowed whole with a glass of water and not chewed, crushed, or broken. The exact dosage and duration of treatment will be determined by a healthcare professional based on individual patient factors, including the severity of hyperglycemia and response to the medication. Consistent adherence to the prescribed dose and accompanying diet and exercise regimen is crucial for optimal benefits.

Side Effects Common side effects may include:

• Hypoglycemia (low blood sugar levels), especially with missed meals, excessive exercise, or alcohol consumption.
• Nausea, vomiting, diarrhea, stomach ache, and changes in taste.
• Weight gain and edema (swelling).
• Headache and dizziness.
• Respiratory infection.

Serious side effects, though less common, can include:

• Lactic acidosis (characterized by abdominal pain, muscle cramps, severe fatigue, and difficulty breathing), which requires immediate medical attention.
• Symptoms of heart failure (unusual shortness of breath, rapid weight gain, localized swelling).

Precautions

• Contraindications: This medicine is not recommended for individuals with Type 1 Diabetes Mellitus, diabetic ketoacidosis, severe kidney or liver disease, bladder cancer, severe heart failure, or a known allergy to any of its components.
• Pregnancy and Breastfeeding: GLYCINORM TOTAL 30 MG TABLET is generally not recommended during pregnancy or breastfeeding.
• Alcohol Consumption: Avoid alcohol as it can increase the risk of lactic acidosis and low blood sugar.
• Driving and Machinery: May cause vision problems, dizziness, or sleepiness, so caution is advised when driving or operating heavy machinery.
• Pre-existing Conditions: Inform your doctor about any history of heart disease, eye problems, hormonal imbalances, or if you are malnourished or on an irregular diet. Regular monitoring of blood sugar levels and kidney function is essential.

Storage Store GLYCINORM TOTAL 30 MG TABLET below 30°C or at room temperature.

Glycinorm Total 30 MG Tablet: Frequently Asked Questions

What is Glycinorm Total 30 MG Tablet used for?

Glycinorm Total 30 MG Tablet is an antidiabetic medicine primarily used in adults to manage Type 2 Diabetes Mellitus. It is prescribed when diet, exercise, and treatment with single antidiabetic agents do not adequately control blood sugar levels. This medication helps improve glycemic control and can potentially prevent long-term complications associated with diabetes, such as kidney damage, nerve problems, blindness, limb amputation, and sexual dysfunction. It may also help reduce the risk of heart attacks and strokes in diabetic patients.

How does Glycinorm Total 30 MG Tablet work?

Glycinorm Total 30 MG Tablet is a combination of three antidiabetic medicines: Gliclazide, Metformin, and Pioglitazone.

• Gliclazide (a sulfonylurea) works by stimulating the pancreas to release more insulin.
• Metformin (a biguanide) reduces glucose production in the liver, delays glucose absorption from the intestines, and increases the body's sensitivity to insulin.
• Pioglitazone (a thiazolidinedione) improves insulin sensitivity in muscles and fat tissues and decreases the amount of glucose released by the liver. Together, these ingredients work through different mechanisms to provide better control of blood sugar levels.

What is the usual dosage of Glycinorm Total 30 MG Tablet?

The dosage of Glycinorm Total 30 MG Tablet should be taken as directed by your doctor. It is typically taken with food, preferably at the same time each day, to avoid stomach upset. Your doctor will determine the appropriate dose based on your individual needs and response to treatment, and this may change over time based on your blood sugar levels. It is crucial not to exceed the prescribed dosage and to continue taking the medicine even if you feel well, unless advised by your doctor.

What are the possible side effects of Glycinorm Total 30 MG Tablet?

Common side effects include low blood sugar levels (hypoglycemia), nausea, vomiting, diarrhea, stomach pain, headache, dizziness, constipation, sore throat, muscle pain, changes in taste, and weight gain. Symptoms of low blood sugar can include sweating, dizziness, confusion, weakness, shakiness, and a fast heartbeat. If you experience these symptoms, it's important to consume a quick source of glucose like fruit juice or sugary candy. More serious side effects can include severe allergic reactions, signs of lactic acidosis (deep breathing, muscle pain, extreme tiredness), and sudden swelling. Consult your doctor if any side effect worsens or if you experience severe symptoms.

Is Glycinorm Total 30 MG Tablet safe during pregnancy or breastfeeding?

Glycinorm Total 30 MG Tablet is generally not recommended for use during pregnancy or while breastfeeding. There is limited information about its effects during human pregnancy and data suggests the drug may pass into breastmilk. Your doctor will weigh the benefits and potential risks before prescribing it if absolutely necessary, or may suggest alternative treatment options.

Can Glycinorm Total 30 MG Tablet be taken with other medications?

Glycinorm Total 30 MG Tablet can interact with various other medications.

• Miconazole and fluconazole (antifungal agents) are generally not recommended as they can increase the concentration of Glycinorm Total 30 MG Tablet, potentially leading to hypoglycemia.
• Concomitant use with alcohol is not recommended as it can increase the risk of lactic acidosis and low blood sugar levels.
• Some medications like glucocorticoids (e.g., prednisolone) or danazol may increase blood sugar levels, reducing the desired effect of Glycinorm Total.
• Other antidiabetic agents, pain killers (e.g., aspirin), certain antibiotics (e.g., tetracyclines, chloramphenicol, ciprofloxacin), and specific male sex hormone replacement therapies can also interact. Always inform your doctor about all medicines, herbal preparations, and supplements you are currently taking to avoid possible drug interactions.

What precautions should be taken?

Several precautions should be observed:

• Contraindications: Glycinorm Total 30 MG Tablet is not recommended for patients with Type 1 diabetes mellitus, severe kidney or liver problems, severe heart failure, bladder cancer, diabetic ketoacidosis, lactic acidosis, or those who are allergic to its ingredients.
• Alcohol: Avoid alcohol consumption as it increases the risk of lactic acidosis and hypoglycemia.
• Liver/Kidney problems: Use with caution, and regular monitoring of liver and kidney function may be advised.
• Heart disease: Caution is advised, especially if you have a history of heart failure, as one of its components (pioglitazone) has been known to induce it.
• Driving/Operating Machinery: This medicine may cause dizziness, changes in vision, or low blood sugar, which can affect alertness. Avoid driving or operating heavy machinery if you experience these effects.
• Lifestyle: It is an essential part of a treatment program that includes a healthy diet, regular exercise, and weight management.

What happens if a dose is missed?

If you miss a dose of Glycinorm Total 30 MG Tablet, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one. Skipping doses can lead to uncontrolled blood sugar levels.

How should it be stored?

Glycinorm Total 30 MG Tablet should be stored at room temperature (below 25°C or 30°C) in a cool and dry place. Protect it from light and moisture, and keep it in a tightly sealed container. Ensure it is out of reach and sight of children and pets. Always check the expiry date before use.