Dapaturn Sm Forte 10mg Tab

DAPATURN SM FORTE 10MG TAB by LUPIN LTD

Name

• Common/Brand Name: Dapaturn SM Forte 10mg Tablet
• Manufacturer: Lupin Ltd.

Composition

Dapaturn SM Forte 10mg Tablet contains a combination of three active ingredients:

• Dapagliflozin 10 mg
• Metformin Hydrochloride 1000 mg
• Sitagliptin 100 mg

Uses

Dapaturn SM Forte is an antidiabetic medicine primarily used for the management of Type 2 Diabetes Mellitus in adults. It is prescribed to improve blood sugar control, especially when diet, exercise, and therapy with conventional medicines do not provide an adequate response, or when more stringent control is required beyond dual combination therapy. This medication helps in the proper utilization of insulin, lowers blood sugar levels, and may also assist with weight loss. It can reduce the risk of death from cardiovascular disease in patients with Type 2 diabetes and existing cardiovascular disease, as well as protect the heart and kidneys.

Dosage and Administration

This medicine should be taken as advised by a healthcare professional. It can be taken with or without food, though taking it with meals may help to reduce gastrointestinal discomfort. The tablet should be swallowed whole and not crushed, broken, or chewed. For optimal results, it is best to take it consistently at the same time each day. Do not discontinue the medication without consulting your doctor.

Side Effects

• Common Side Effects: Hypoglycemia (low blood glucose level), nausea, vomiting, abdominal pain, headache, flatulence, genital infections (e.g., fungal infections), increased or more frequent urination, urinary tract infections, nasal congestion, sore throat, upper respiratory tract infections, diarrhea, drowsiness, dizziness, itching, dry mouth, decreased weight, and a bad taste in the mouth.
• Serious Side Effects (Seek medical attention if experienced): Symptoms of lactic acidosis (weakness, breathing difficulty, severe stomach pain), ketoacidosis (nausea, vomiting, confusion, fruity breath), acute pancreatitis (severe, persistent abdominal pain often radiating to the back), severe allergic reactions (rash, hives, swelling of face/lips/tongue, difficulty breathing), bullous pemphigoid (blistering of the skin), or Fournier's gangrene (pain, tenderness, redness, or swelling in the genital or perineal area accompanied by fever or general discomfort).

Precautions

Dapaturn SM Forte is not recommended for individuals with Type 1 diabetes or diabetic ketoacidosis. Patients should inform their doctor about any allergies to its components, as well as their medical history, especially severe liver or kidney disease, heart failure, respiratory failure, or a recent myocardial infarction. It is important to disclose all medications, including other antidiabetic drugs (like insulin or sulfonylureas), diuretics, and certain heart or blood pressure medications. This medicine is not recommended for children under 18 years of age. Pregnant or breastfeeding women should consult their doctor, as it is generally not recommended during these periods. Avoid excessive alcohol consumption due to an increased risk of hypoglycemia and lactic acidosis. Regular monitoring of blood sugar levels and kidney function is advised.

Storage

Store Dapaturn SM Forte in a cool and dry place, away from direct sunlight, and out of the sight and reach of children. It should be stored at or below 30°C.

Here are some frequently asked questions about DAPATURN SM FORTE 10MG TAB:

What is DAPATURN SM FORTE 10MG TAB used for?

DAPATURN SM FORTE 10MG TAB is a combination medication primarily used for the management of type 2 diabetes mellitus in adults whose blood sugar levels are not adequately controlled by metformin alone, or other conventional therapies. It helps to improve blood sugar control and can also reduce the risk of serious complications such as kidney damage, nerve problems, and eye damage. Additionally, it may help lower the risk of cardiovascular events and hospitalizations for heart failure in patients with type 2 diabetes and related conditions.

How does DAPATURN SM FORTE 10MG TAB work?

This medicine contains three active ingredients: Dapagliflozin, Metformin, and Sitagliptin.

• Dapagliflozin is a sodium-glucose cotransporter-2 (SGLT2) inhibitor that works by increasing the removal of excess glucose from the body through urine.
• Metformin is a biguanide that reduces the amount of sugar produced by the liver, delays glucose absorption from the intestines, and improves the body's sensitivity to insulin.
• Sitagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that helps control blood sugar levels by increasing the release of insulin and signaling the liver to stop producing sugar when blood sugar levels are high. The combined action of these three components offers a multi-targeted approach to control blood sugar levels.

What is the usual dosage for DAPATURN SM FORTE 10MG TAB?

DAPATURN SM FORTE 10MG TAB should be taken exactly as advised by your doctor. The dosage is determined by your doctor based on your condition and response to treatment. It can be taken with or without food, but it is recommended to take it at the same time each day for consistency. Do not take more than the prescribed dose, and it's important not to discontinue the medication without your doctor's guidance.

What are the possible side effects of DAPATURN SM FORTE 10MG TAB?

Common side effects may include urinary tract infections (UTIs), nasal congestion, sore throat, upper respiratory tract infections, headache, nausea, vomiting, and diarrhea. Some individuals might experience fungal infections in the genital area. Serious, but rare, side effects can include lactic acidosis, ketoacidosis, acute pancreatitis, and allergic reactions (such as swelling of the face, tongue, and lips). If you experience persistent or severe side effects, or symptoms like continuous and severe abdominal pain, excessive thirst, confusion, or severe nausea/vomiting, you should consult your doctor immediately.

Is DAPATURN SM FORTE 10MG TAB safe during pregnancy or breastfeeding?

There is limited information on the effect of DAPATURN SM FORTE 10MG TAB during pregnancy, and it is generally not recommended for use in pregnant women. Similarly, there is no information available on whether this medicine passes into human breast milk, so it should not be used by breastfeeding women. Always inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding before starting this medication.

Can DAPATURN SM FORTE 10MG TAB be taken with other medications?

DAPATURN SM FORTE 10MG TAB can interact with other medications, so it's crucial to inform your doctor about all other medicines, herbal supplements, or vitamins you are currently taking or plan to take. Particular caution should be exercised with:

• Diuretics (water pills) like furosemide or hydrochlorothiazide, as they may increase the risk of dehydration and low blood pressure.
• Insulin and insulin secretagogues (like sulfonylureas), as concurrent use may cause extremely low blood sugar levels (hypoglycemia).
• Medicines for fungal infections (e.g., ketoconazole, itraconazole), bacterial infections (e.g., clarithromycin), or HIV/AIDS (e.g., ritonavir).
• Blood pressure drugs and steroids.
• Lithium may have reduced serum levels when taken with dapagliflozin.

What precautions should be taken while using DAPATURN SM FORTE 10MG TAB?

Before taking DAPATURN SM FORTE 10MG TAB, inform your doctor if you have type 1 diabetes, severe kidney or liver disease, heart failure, a history of low blood pressure, or acute pancreatitis. Avoid excessive alcohol consumption, as it can increase the risk of complications like diabetic ketoacidosis and lactic acidosis. It is essential to drink plenty of fluids to prevent dehydration. If you are scheduled for surgery, your doctor may advise you to temporarily stop this medication. Regular monitoring of blood sugar levels and kidney function is important during treatment.

What happens if a dose of DAPATURN SM FORTE 10MG TAB is missed?

If you miss a dose of DAPATURN SM FORTE 10MG TAB, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one, as this may cause your blood sugar level to fall rapidly.

How should DAPATURN SM FORTE 10MG TAB be stored?

Store DAPATURN SM FORTE 10MG TAB in a cool and dry place, away from direct sunlight and moisture. Keep it out of the sight and reach of children.