Trigabantin 100 Mg Tablet (10 Tab)

TRIGABANTIN 100 MG TABLET

TRIGABANTIN 100 MG TABLET is a combination medicine manufactured by SUN PHARMA LABORATORIES LTD., primarily used to treat neuropathic pain.

Composition

Each tablet contains:

• Gabapentin: 100 mg
• Alpha Lipoic Acid: 100 mg
• Methylcobalamin: 500 mcg (Vitamin B12)

Uses

TRIGABANTIN 100 MG TABLET is prescribed for the treatment of neuropathic pain, which is chronic nerve pain resulting from damaged sensory nerves. It may be used for various conditions including:

• Diabetic neuropathy
• Postherpetic neuralgia (nerve pain after shingles)
• Drug-induced neuropathy
• Alcoholic neuropathy
• Trigeminal neuralgia
• Reflex Sympathetic Dystrophy Syndrome

Gabapentin, an anti-convulsant, modulates calcium channel activity in brain cells to decrease pain. Methylcobalamin helps in the rejuvenation and protection of damaged nerve cells by aiding myelin production. Alpha-lipoic acid acts as an antioxidant, providing a protective effect on nerve tissues and the brain.

Dosage and Administration

TRIGABANTIN 100 MG TABLET should be taken orally as directed by a healthcare professional. It can be taken with or without food, but it is best to maintain consistency daily. Swallow the tablet whole with a glass of water; do not chew, crush, or break it.

Dosage is typically started low and gradually increased by the doctor to allow the body to adjust and minimize side effects. For pain management, the usual target dose for Gabapentin is often around 1800 mg/day, administered in three divided doses. Do not stop taking this medication suddenly without consulting your doctor, as abrupt discontinuation can lead to withdrawal symptoms, including increased pain, anxiety, sweating, and potentially seizures.

Side Effects

Common side effects may include:

• Dizziness
• Sleepiness or drowsiness
• Tiredness or weakness
• Nausea and vomiting
• Headache
• Unsteadiness or coordination problems
• Weight gain
• Dry mouth
• Blurred or double vision

Serious side effects are rare but require immediate medical attention:

• Changes in mood, behavior, or thoughts (e.g., suicidal thoughts)
• Signs of an allergic reaction (e.g., hives, rash, itching, swelling of face/lips/tongue/throat, difficulty breathing)
• Severe breathing problems (especially with other CNS depressants)
• High temperature, swollen glands, yellowing of skin/eyes, unusual bruising/bleeding (may indicate DRESS or liver issues)

Precautions

• Kidney Disease: Use with caution in patients with kidney disease; dose adjustments may be necessary.
• Mental Health: Gabapentin may cause unexpected changes in mental health, including depression and suicidal thoughts.
• CNS Depressants & Alcohol: Avoid alcohol and consult your doctor about other CNS depressants (e.g., opioids, benzodiazepines, muscle relaxants, sleep medications), as they can increase drowsiness and the risk of severe breathing problems.
• Antacids: If taking antacids like Maalox or Mylanta, take them at least 2 hours before or after TRIGABANTIN.
• Driving/Operating Machinery: This medication can cause drowsiness, dizziness, and coordination problems. Do not drive or operate machinery until you know how it affects you.
• Sudden Discontinuation: Do not stop taking this medicine abruptly. Your doctor will provide a plan for gradual dose reduction to prevent withdrawal symptoms and increased seizure risk.
• Pregnancy and Breastfeeding: Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Storage

Store tablets at room temperature, generally between 15°C and 30°C (59°F and 86°F), away from moisture, heat, and direct light. Keep out of reach of children and pets. Dispose of any unused or expired medication properly.

TRIGABANTIN 100 MG TABLET (10 TAB) by SUN PHARMA LABORATORIES LTD. - Frequently Asked Questions

What is Trigabantin 100 mg Tablet used for?

Trigabantin 100 mg Tablet is a combination medication primarily used to treat neuropathic pain. This type of pain results from nerve damage caused by various conditions such as diabetic neuropathy, postherpetic neuralgia (pain after shingles), trigeminal neuralgia, and other neurological disorders. It helps to alleviate pain symptoms and improve nerve health.

How does Trigabantin 100 mg Tablet work?

Trigabantin 100 mg Tablet contains three active ingredients: Gabapentin, Methylcobalamin (Vitamin B12), and Alpha-lipoic acid. Gabapentin works by modulating the activity of calcium channels in nerve cells, which helps to reduce pain signals. Methylcobalamin supports the rejuvenation and protection of damaged nerve cells by assisting in the production of myelin, a substance that insulates nerve fibers. Alpha-lipoic acid provides antioxidant effects and helps protect nerve tissues and the brain. Together, these ingredients work to relieve neuropathic pain and support nerve regeneration.

What is the usual dosage for Trigabantin 100 mg Tablet?

The dosage of Trigabantin 100 mg Tablet should be strictly followed as prescribed by your doctor. It can generally be taken with or without food, but some sources suggest taking it on an empty stomach for optimal efficacy. It is important to swallow the tablet whole with water and not to crush, chew, or break it. Adhering to a consistent daily schedule for intake helps maintain a stable level of the medication in your body.

What are the possible side effects of Trigabantin 100 mg Tablet?

Common side effects may include dizziness, sleepiness, tiredness, nausea, vomiting, headache, changes in appetite and mood, visual disturbances, and uncoordinated body movements. Some individuals may also experience weight gain, dry mouth, or stomach pain. These mild side effects often diminish over time. More serious but rare side effects can include allergic reactions (such as rash, itching, or swelling), suicidal thoughts, or swelling of the hands, legs, or feet. If any side effects persist or worsen, or if you experience serious symptoms, consult your doctor immediately.

Is Trigabantin 100 mg Tablet safe during pregnancy or breastfeeding?

Trigabantin 100 mg Tablet is generally not recommended for use during pregnancy unless absolutely necessary, and only after a thorough discussion of potential risks and benefits with your doctor. Animal studies have indicated possible harm to the developing baby. Similarly, it is probably unsafe during breastfeeding as the medication can pass into breast milk. Always consult your healthcare provider before taking this medicine if you are pregnant, planning a pregnancy, or breastfeeding.

Can Trigabantin 100 mg Tablet be taken with other medications?

It is important to inform your doctor about all other medications, herbal preparations, and supplements you are currently taking to avoid potential drug interactions. Antacids should be avoided within 2 hours of taking Trigabantin 100 mg Tablet as they may interfere with its absorption. Concomitant use with opioid medicines may increase sleepiness and difficulty breathing, requiring caution. While generally considered safe with metformin, always confirm with your doctor.

What precautions should be taken while using Trigabantin 100 mg Tablet?

Avoid consuming alcohol while taking Trigabantin 100 mg Tablet as it can increase dizziness and drowsiness. Due to the potential for dizziness and sleepiness, do not drive or operate heavy machinery until you understand how the medicine affects you. Do not stop taking the medication suddenly without consulting your doctor, as this can lead to withdrawal symptoms like convulsions. Inform your doctor if you have pre-existing conditions such as heart issues, bipolar syndrome, nervous system disorders, kidney disease, or respiratory illness, or if you are over 65 years old. Monitor for any unusual changes in mood or behavior, new or worsening depression, or suicidal thoughts.

What happens if a dose of Trigabantin 100 mg Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed one and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should Trigabantin 100 mg Tablet be stored?

Trigabantin 100 mg Tablet should be stored in a cool, dry place, ideally below 25°C. Keep it away from direct sunlight and out of the reach of children.