Doxinamac Plus Tab

DOXINAMAC PLUS TAB

Name:

• Brand Name: Doxinamac Plus Tablet
• Manufacturer: MACLEODS-PHARMACORE DIV. (Macleods Pharmaceuticals Ltd.)

Composition: Each tablet typically contains:

• Doxylamine Succinate: 10 mg
• Pyridoxine Hydrochloride (Vitamin B6): 10 mg
• Folic Acid (Vitamin B9): 2.5 mg

Uses: DOXINAMAC PLUS TAB is primarily used to treat nausea and vomiting during pregnancy, commonly known as morning sickness. It works by blocking certain chemicals in the body that trigger nausea and vomiting. Additionally, it provides essential nutrients required during pregnancy, with Folic acid aiding in healthy fetal development (brain and spinal cord) and Pyridoxine contributing to metabolism and reducing nausea.

Dosage and Administration: This medicine should be taken exactly as prescribed by a doctor. It is typically advised to take the tablet whole with a glass of water, preferably on an empty stomach for better absorption. The usual dose for Doxinamac-Plus Tablet is 2 tablets at bedtime. If symptoms persist, a doctor may recommend up to 4 tablets per day (2 at bedtime and 2 in the morning). Do not chew, crush, or break the tablet, and do not exceed the recommended dose.

Side Effects: Common side effects include:

• Dizziness
• Drowsiness/Sleepiness
• Dry Mouth
• Tiredness/Fatigue
• Constipation

Other less common side effects may include lightheadedness, blurred eyesight, restlessness, rashes, itching, vertigo, abdominal pain, diarrhea, urinary retention, and insomnia. If any side effects persist or worsen, consult a doctor.

Precautions:

• Driving and Operating Machinery: This medicine can cause dizziness and drowsiness, therefore, avoid driving or operating heavy machinery until you know how it affects you.
• Alcohol: Avoid consuming alcohol while taking Doxinamac Plus Tablet, as it can intensify drowsiness.
• Allergies: Do not take this medicine if you are allergic to doxylamine, pyridoxine, folic acid, or any other ingredients.
• Medical Conditions: Inform your doctor if you have a history of asthma, glaucoma, stomach ulcers, blockages in the stomach, small intestine, or bladder, or vitamin B12 deficiency.
• Other Medications: Inform your doctor about all other medications you are taking, including over-the-counter medicines and herbal preparations. Avoid use with monoamine oxidase (MAO) inhibitors (antidepressants). Caution is advised with anticoagulants, sleeping pills, pain killers, and cough/cold medicines. Pyridoxine may reduce the effects of Levodopa, Phenobarb, and Phenytoin.
• Pregnancy: Doxinamac Plus Tablet is generally considered safe for use during pregnancy when prescribed by a doctor.
• Breastfeeding: Use with caution during breastfeeding, as doxylamine can pass into breast milk and may cause sedation and irritability in infants. A doctor may advise stopping breastfeeding if prescribed.
• Children: Not recommended for use in children under 18 years old.
• Discontinuation: Do not stop taking this medicine without consulting your doctor.

Storage: Store Doxinamac Plus Tablet below 25°C to 30°C in a clean and dry place. Protect it from moisture, sunlight, and heat. Keep this medicine out of the sight and reach of children and pets.

What is Doxinamac Plus Tablet used for?

Doxinamac Plus Tablet is primarily used to treat nausea and vomiting experienced during pregnancy, commonly known as morning sickness. It helps alleviate queasiness, nausea, and vomiting often associated with the early stages of pregnancy. Additionally, it provides nutritional support for fetal development due to the inclusion of folic acid and pyridoxine (vitamin B6).

How does Doxinamac Plus Tablet work?

Doxinamac Plus Tablet is a combination medicine containing Doxylamine, Pyridoxine (Vitamin B6), and Folic Acid (Vitamin B9). Doxylamine is an antihistamine that works by blocking natural chemicals (histamine) in the body, thereby preventing nausea and vomiting. Pyridoxine, or Vitamin B6, helps by restoring its levels in the body, as its deficiency can contribute to nausea and vomiting during pregnancy. Folic acid is an essential B vitamin that aids in DNA synthesis, cell division, and the healthy development of the baby's brain and spinal cord, while also supporting overall pregnancy nutrition.

What is the usual dosage for Doxinamac Plus Tablet?

The dosage of Doxinamac Plus Tablet should be taken exactly as prescribed by your doctor. A common starting dose for treating nausea and vomiting during pregnancy is two tablets taken at bedtime. Depending on symptom control, the dose may be adjusted. For example, if symptoms persist, your doctor might recommend taking one tablet in the morning and two tablets at bedtime, or one tablet in the morning, one in the mid-afternoon, and two at bedtime. It is important not to exceed the recommended dose.

What are the possible side effects of Doxinamac Plus Tablet?

Common side effects of Doxinamac Plus Tablet include dizziness, drowsiness, dry mouth, tiredness, and constipation. These side effects are usually mild and temporary. If any of these side effects persist or worsen, it is advisable to inform your doctor.

Is Doxinamac Plus Tablet safe during pregnancy or breastfeeding?

Doxinamac Plus Tablet is considered safe for use during pregnancy when prescribed by a doctor, as its primary use is to manage nausea and vomiting in pregnant women. However, it should be used with caution during breastfeeding because doxylamine can pass into breast milk and may cause sedation and irritability in breastfeeding infants. If prescribed while breastfeeding, your doctor may advise you to stop breastfeeding.

Can Doxinamac Plus Tablet be taken with other medications?

Doxinamac Plus Tablet can interact with certain medications. It is not recommended to use it with monoamine oxidase (MAO) inhibitors (antidepressants) or sleeping pills, as this can worsen side effects. You should also inform your doctor if you are taking anticoagulant (blood thinners) therapy, other pain relievers, or cough and cold medicines. Pyridoxine in the tablet can also reduce the effects of medications like Levodopa, Phenobarb, and Phenytoin. Always inform your doctor about all other medications, over-the-counter drugs, and herbal preparations you are taking.

What precautions should be taken while taking Doxinamac Plus Tablet?

Doxinamac Plus Tablet may cause drowsiness and dizziness, so it is important to avoid driving or operating heavy machinery until you know how the medicine affects you. Alcohol consumption should be avoided as it can increase drowsiness. Inform your doctor if you have conditions such as asthma, glaucoma, stomach ulcers, obstruction in the stomach or intestines, or bladder obstruction. It is not recommended for use in children without medical supervision.

What happens if a dose of Doxinamac Plus Tablet is missed?

If you miss a dose of Doxinamac Plus Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should Doxinamac Plus Tablet be stored?

Doxinamac Plus Tablet should be stored in a cool and dry place, away from direct sunlight, moisture, and heat, ideally below 25°C or 30°C. Keep the medicine in its original container, tightly closed, and out of the sight and reach of children and pets. Do not use the medicine if it is expired.