Pancef O 100 Mg Dry Syrup

PANCEF O 100 MG DRY SYRUP by AGLOWMED LTD

PANCEF O 100 MG DRY SYRUP is an antibiotic medication primarily used for the management of various bacterial infections in children.

Name

• Brand Name: PANCEF O 100 MG DRY SYRUP (often referred to as PANCEF O 100 PINEAPPLE FLAVOUR DRY SYRUP)
• Common Name (Active Ingredient): Cefixime

Composition The active ingredient in PANCEF O 100 MG DRY SYRUP is Cefixime, at a concentration of 100 mg per 5 ml of the reconstituted syrup. Cefixime belongs to the group of medicines called cephalosporin antibiotics, which work by stopping the growth of bacteria by interfering with the synthesis of their cell walls, ultimately killing the bacteria.

Uses PANCEF O 100 MG DRY SYRUP is prescribed for the short-term management of various bacterial infections, including:

• Ear infections (such as otitis media)
• Nose, throat, and sinus infections (e.g., tonsillitis, pharyngitis, sinusitis)
• Chest and lung infections (such as bronchitis and pneumonia)
• Urinary tract infections (e.g., cystitis, kidney infections)
• Skin and soft-tissue infections
• Typhoid fever
• Some sexually transmitted diseases (e.g., uncomplicated cervical or urethral gonorrhoea)

It is important to note that this antibiotic is effective only against bacterial infections and will not work for viral infections like the common cold or flu.

Dosage and Administration Administer PANCEF O 100 MG DRY SYRUP as directed by a physician.

• Preparation: Shake the bottle to disperse the powder. Pour the sterile water (often provided with the pack) into the bottle up to the mark. Close the bottle and shake it vigorously to ensure the powder dissolves completely and there are no lumps.
• Administration: The prepared suspension is for oral use. It can be taken with or without food, but taking it at a fixed time each day is recommended to ensure optimal results and aid in remembering doses.
• Duration: The dose and duration of therapy will be determined by the doctor based on the child's age, body weight, and the severity of the infection. It is crucial to complete the entire prescribed course of treatment, even if symptoms improve, to prevent the infection from returning or becoming harder to treat and to avoid antibiotic resistance.

Side Effects

• Common Side Effects: Nausea, vomiting, diarrhea (which may be watery), stomach pain, indigestion, loose stools, bloating, headache, dizziness, flatulence, anorexia, pruritus ani (itching around the anus), dry mouth, and itchiness of the genital or vaginal areas.
• Serious Side Effects (Seek immediate medical attention if experienced):
  • Signs of severe allergic reactions (e.g., skin rash, intense itching, swelling of the face, lips, throat, or tongue, difficulty breathing or swallowing).
  • Unusual bleeding or bruising, bleeding from the nose or gums, pale skin, tiredness, chills, and shortness of breath.
  • Severe, uncontrollable watery diarrhea, feeling weak, and fever (these could be signs of stomach damage).
  • Seizures or encephalopathy (damage or disease affecting the brain).

Precautions

• Allergies: This medicine is contraindicated in children with a known history of allergy to Cefixime or any other cephalosporin antibiotics, including penicillins.
• Kidney and Liver Issues: Use with caution in children with kidney problems. Inform the doctor if the child has any history of kidney or liver problems.
• Gastrointestinal Conditions: Inform the doctor if the child has any stomach problems, including a history of colitis.
• Drug Interactions:
  • Concomitant use with anticoagulants (e.g., Warfarin) may increase prothrombin time and the risk of unusual bleeding.
  • May increase plasma concentrations of Carbamazepine (used to treat seizures).
  • Increased bioavailability with Nifedipine and increased serum concentration with Probenecid.
  • May increase the risk of kidney damage when taken with nephrotoxic drugs like aminoglycosides.
• Antibiotic Resistance: Do not use this medicine for viral infections. Completing the full course as prescribed is essential to prevent antibiotic resistance.
• Pregnancy and Breastfeeding: For adults, limited safety information is available during pregnancy; it should only be used if considered essential by a doctor. It is unknown if Cefixime passes into breastmilk, so consultation with a doctor is necessary for breastfeeding mothers.
• Driving: In adults, side effects like confusion, altered consciousness, or fits can occur, making driving or operating machinery unsafe.

Storage Store PANCEF O 100 MG DRY SYRUP below 25°C or 30°C, protected from direct sunlight, heat, and moisture. Keep it out of the reach and sight of children and pets. The reconstituted syrup should be stored in the refrigerator and used within the timeframe specified on the product label.

What is PANCEF O 100 MG DRY SYRUP used for?

PANCEF O 100 MG DRY SYRUP is an antibiotic primarily used in children to treat a variety of bacterial infections. These include infections of the ear, nose, sinuses (sinusitis), throat (tonsillitis, pharyngitis), chest and lungs (bronchitis, pneumonia), and the urinary system (cystitis and kidney infections). It is also effective for skin and soft-tissue infections and typhoid fever.

How does PANCEF O 100 MG DRY SYRUP work?

This medicine contains Cefixime, which is a third-generation cephalosporin antibiotic. It works by inhibiting the synthesis of the bacterial cell wall, a protective covering essential for bacteria to survive. By weakening and destroying the cell wall, Cefixime ultimately kills the bacteria, thus treating the infection.

What is the usual dosage for PANCEF O 100 MG DRY SYRUP?

The dosage depends on the child's age, weight, and the severity of the infection, and should always be prescribed by a doctor. For children aged 6 months to 12 years weighing less than 50 kg, the recommended dose is typically 8 mg per kg of body weight per day, which can be given as a single dose or in two divided doses. For children older than 10 years or weighing over 50 kg, the adult dose (200-400 mg daily) is usually recommended. The usual course of treatment is 7 to 14 days, and it's important to take it at evenly spaced intervals.

How should PANCEF O 100 MG DRY SYRUP be prepared and administered?

To prepare the dry syrup, you should add boiled and cooled water to the dry powder and shake it thoroughly until it reaches the mark on the bottle. Shake the bottle well before each use to ensure the medicine is evenly mixed. This medication is taken orally and can be given with or without food; however, taking it with food may help reduce stomach upset. Always use a measuring cup or spoon provided for accurate dosing.

What are the possible side effects of PANCEF O 100 MG DRY SYRUP?

Common side effects include diarrhea, nausea, vomiting, stomach pain, loose stools, indigestion, dyspepsia, gas, headache, and dizziness. If diarrhea becomes severe, watery, or bloody, or if you notice signs of an allergic reaction like skin rash, itching, swelling of the face, lips, throat, or tongue, seek immediate medical attention.

Is PANCEF O 100 MG DRY SYRUP safe during pregnancy or breastfeeding?

Pregnancy: There is limited safety data available, and PANCEF O should only be used during pregnancy if considered essential by a doctor and if the benefits outweigh the potential risks. It is classified as Pregnancy Category B by the FDA.

Breastfeeding: It is unknown if Cefixime passes into breast milk. While adverse effects are unlikely, infants should be monitored closely. Temporary discontinuation of nursing may be recommended by the manufacturer during treatment. Always consult your doctor before using this medicine if pregnant or breastfeeding.

Can PANCEF O 100 MG DRY SYRUP be taken with other medications?

Yes, PANCEF O can interact with certain medications. It may increase the effect of blood thinners like Warfarin, increasing the risk of bleeding. It can also increase the concentration of Carbamazepine (used for seizures) and Probenecid. Antacids and iron supplements may decrease the absorption of Cefixime, so it's advisable to separate their administration by at least 2 hours. Cefixime may also reduce the effectiveness of oral contraceptives. Always inform your doctor about all other medicines, supplements, or herbal products being taken to avoid potential interactions.

What precautions should be taken while using PANCEF O 100 MG DRY SYRUP?

It is crucial to complete the entire prescribed course of the medication, even if symptoms improve, to prevent the infection from returning and to avoid antibiotic resistance. This antibiotic is only effective against bacterial infections and will not work for viral infections like the common cold or flu. Inform your doctor if there is a history of allergies, especially to penicillin or other cephalosporin antibiotics, or if there are kidney or liver problems. Avoid consuming alcohol while taking this antibiotic.

What happens if a dose of PANCEF O 100 MG DRY SYRUP is missed?

If a dose is missed, take it as soon as you remember. However, if it is almost time for the next scheduled dose, skip the missed dose and continue with the regular dosing schedule. Do not take a double dose to make up for a missed one.

How should PANCEF O 100 MG DRY SYRUP be stored?

The dry powder should be stored in a cool and dry place, away from direct sunlight, heat, and moisture, typically below 25°C or 30°C. Keep it out of the reach and sight of children and pets. Once reconstituted with water, the syrup should be stored in the refrigerator and used within the timeframe specified on the label, which is usually 14 days.