Pregadoc Nt Tablet (10 Tab)

PREGADOC NT TABLET (10 TAB) by LUPIN LTD.

Name

• Brand Name: PREGADOC NT TABLET

Composition

PREGADOC NT TABLET is a combination medication containing:

• Pregabalin: 75 mg
• Nortriptyline: 10 mg

Uses

This medication is prescribed for the management of neuropathic pain, which is pain caused by nerve damage. It is effective for conditions such as:

• Diabetic neuropathy
• Post-herpetic neuralgia (nerve pain after shingles)
• Fibromyalgia
• Pain associated with spinal cord injury
• Peripheral neuropathy It also helps alleviate associated symptoms like mood changes, sleep disturbances, and fatigue.

Dosage and Administration

PREGADOC NT TABLET should be taken exactly as prescribed by a healthcare provider, typically once or twice a day. The tablet should be swallowed whole with a glass of water and not crushed or chewed. It can be taken with or without food; taking it with food may help reduce stomach upset. Abrupt discontinuation of the medication is not recommended due to potential withdrawal symptoms.

Side Effects

• Common Side Effects: Dizziness, sleepiness, dry mouth, weight gain, blurred vision, constipation, nausea, fatigue, increased appetite, and swelling in the hands or feet (peripheral edema).
• Serious Side Effects (rare): These can include severe allergic reactions (rash, itching, swelling), thoughts of self-harm or suicide, chest pain, irregular heartbeat, or significant mood changes.

Precautions

• Alcohol: Avoid consuming alcohol as it can increase drowsiness and dizziness.
• Alertness: This medicine may cause drowsiness or blurred vision; therefore, avoid driving or operating heavy machinery until you understand how it affects you.
• Medical Conditions: Inform your doctor about any history of kidney or liver problems, heart conditions, bipolar disorder, or seizures.
• Pregnancy and Breastfeeding: Generally not recommended during pregnancy or breastfeeding unless specifically advised by a doctor after evaluating the benefits and risks.
• Drug Interactions: Inform your doctor about all other medications you are taking, especially other antidepressants (like MAO inhibitors), anticonvulsants, or pain relievers. A 14-day gap is required between stopping MAO inhibitors and starting PREGADOC NT.
• Sun Sensitivity: May increase sensitivity to sunlight; use protective clothing and sunscreen when outdoors.

Storage

Store PREGADOC NT TABLET in its original packaging in a cool, dry place, away from direct sunlight, heat, and moisture. Keep it out of reach of children and pets.

What is PREGADOC NT TABLET used for?

PREGADOC NT TABLET is a combination medicine primarily used to treat neuropathic pain, which is pain caused by nerve damage. This includes conditions such as diabetic neuropathy, post-herpetic neuralgia (nerve pain after shingles), fibromyalgia, and pain resulting from spinal cord injury. It may also be used in the management of certain types of seizures and generalized anxiety disorder or depression-related symptoms.

How does PREGADOC NT TABLET work?

PREGADOC NT TABLET contains two active ingredients: Pregabalin and Nortriptyline. Pregabalin is an anticonvulsant that works by calming overactive nerve signals in the brain and spinal cord, reducing the release of neurotransmitters that send pain signals. Nortriptyline is a tricyclic antidepressant that increases the levels of chemical messengers like serotonin and norepinephrine in the brain, which helps to stop the movement of pain signals and can also improve mood and reduce anxiety. Together, they provide a dual action to relieve nerve-related pain.

What is the usual dosage of PREGADOC NT TABLET?

The typical starting dose is usually one tablet daily, often taken at bedtime to minimize daytime drowsiness. Your doctor will determine the appropriate dose and duration of treatment based on your condition and how you respond to the medication. It's crucial to take the tablet exactly as prescribed by your doctor, swallowing it whole with a glass of water, and not crushing, chewing, or breaking it. It can be taken with or without food, but it's advisable to take it at a consistent time each day.

What are the possible side effects of PREGADOC NT TABLET?

Common side effects may include dizziness, drowsiness, dry mouth, weight gain, blurred vision, constipation, nausea, fatigue, and swelling in the hands or feet (peripheral edema). If you experience persistent or bothersome side effects, you should inform your healthcare provider. More severe but rare side effects can include unusual mood changes, suicidal thoughts, or signs of an allergic reaction like swelling of the face, lips, or tongue, and difficulty breathing.

Is PREGADOC NT TABLET safe during pregnancy or breastfeeding?

PREGADOC NT TABLET is generally not recommended during pregnancy as it may be unsafe, with limited human studies suggesting potential harmful effects on the developing baby. If you are pregnant, planning a pregnancy, or become pregnant while taking this medicine, consult your doctor immediately. For breastfeeding mothers, it is probably unsafe as limited data suggests the drug may pass into breast milk and could harm the baby. Your doctor will advise on whether to discontinue breastfeeding or the medication.

Can PREGADOC NT TABLET be taken with other medications?

PREGADOC NT TABLET can interact with certain other medications. It is important to inform your doctor about all prescription and over-the-counter medicines, as well as any herbal remedies or supplements you are taking. Significant interactions can occur with opioid pain relievers, antihistamines, medicines for anxiety or sleep, and certain antidepressants, including Monoamine Oxidase Inhibitors (MAOIs), which should not be taken within 14 days of starting PREGADOC NT TABLET.

What precautions should be taken while taking PREGADOC NT TABLET?

Avoid consuming alcohol while taking PREGADOC NT TABLET, as it can increase side effects such as drowsiness and dizziness. This medication may cause drowsiness or blurred vision, so it's advised to avoid driving or operating heavy machinery until you understand how it affects you. Do not stop taking PREGADOC NT TABLET suddenly, as this can lead to withdrawal symptoms; the dose should be gradually reduced under medical supervision. Inform your doctor if you have a history of heart problems, kidney or liver disease, diabetes, glaucoma, or mental health issues.

What happens if a dose of PREGADOC NT TABLET is missed?

If you miss a dose of PREGADOC NT TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one, as this can increase the risk of side effects.

How should PREGADOC NT TABLET be stored?

PREGADOC NT TABLET should be stored in its original packaging in a cool, dry place, away from direct sunlight, heat, and moisture. It is essential to keep the medication out of reach of children and pets to ensure its stability and effectiveness.