Amicline

AMICLINE Tablets, manufactured by FRANCO-INDIAN PHARMACEUTICALS PVT LTD, are an antiprotozoal medicine primarily used for treating intestinal infections.

Name

• Brand Name: AMICLINE® Tablets
• Common Name: Diloxanide Furoate

Composition Each uncoated tablet contains Diloxanide Furoate I.P. 500 mg.

Uses AMICLINE is prescribed for the treatment of various intestinal parasitic infections, including:

• Asymptomatic cyst passers
• Intestinal amoebiasis (amoebic dysentery)
• Other parasitic worm infections It is also used in anti-amoebic therapy for patients allergic to or unable to tolerate Nitroimidazoles. The medicine works by inhibiting the growth of amoeba in the intestines and preventing the spread of infection. It is important to note that AMICLINE alone is not effective for invasive or extraintestinal amoebiasis.

Dosage and Administration Take AMICLINE in the exact dose and duration as recommended by your doctor. It can be taken with or without food, preferably at a fixed time. Swallow the tablet whole with a full glass of water; do not crush, chew, or break it. It is crucial to complete the full course of treatment even if symptoms improve, to ensure all parasites are killed and prevent resistance. Do not take a double dose to compensate for a missed one. This medicine is not recommended for children under 12 years of age or those weighing less than 25 kg.

Side Effects Common side effects may include nausea, headache, stomach pain, vomiting, hair loss, flatulence, diarrhea, dizziness, and abnormal liver function tests. Most of these side effects are temporary and typically resolve over time. If any side effects persist or worsen, consult your doctor.

Precautions

• Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. AMICLINE can be harmful to an unborn baby and should not be taken during pregnancy; birth control measures are advised.
• Caution is advised for patients with liver or kidney problems; your doctor may monitor blood tests and liver function throughout treatment.
• Avoid consuming alcohol while on this medication, as it may worsen side effects like dizziness.
• Do not drive or operate machinery if you experience dizziness.
• Inform your doctor if you are allergic to Diloxanide or any other ingredients in the tablet.

Storage Store AMICLINE Tablets below 25°C. Keep this medicine out of the sight and reach of children.

What is AMICLINE used for?

AMICLINE, manufactured by Franco-Indian Pharmaceuticals Pvt Ltd, is primarily used to treat various parasitic infections, particularly intestinal amoebiasis (amoebic dysentery) and other worm infections. It is also administered to individuals who carry asymptomatic cysts of Entamoeba histolytica.

How does AMICLINE work?

AMICLINE acts as a luminal amoebicide, meaning it works within the bowel to kill the infection-causing amoeba. The active ingredient, diloxanide furoate, is hydrolyzed in the gut to release free diloxanide, which then inhibits the trophozoites of Entamoeba histolytica. It is also believed to work by blocking protein synthesis in the microorganisms.

What is the usual dosage of AMICLINE?

For adults, the recommended dosage is typically 500 mg taken three times a day for a duration of 10 days. Your doctor may advise repeating the course if necessary. It is important to adhere to the prescribed dosage and not to exceed it without consulting your doctor.

What are the possible side effects of AMICLINE?

Common side effects of AMICLINE can include flatulence, nausea, vomiting, abdominal pain or cramps, headache, itching, urticaria (hives), and loss of appetite. In some cases, abnormal liver function tests have been reported. If you experience any severe reactions such as a serious skin rash or difficulty breathing, seek immediate medical attention.

Is AMICLINE safe during pregnancy or breastfeeding?

Caution is advised when using AMICLINE during pregnancy and breastfeeding. It should only be used if the potential benefits outweigh the potential risks, and only under a doctor's guidance. Amicline can potentially cause unwanted side effects in pregnant women. It is generally not recommended for use during breastfeeding, and a doctor should be consulted for alternative treatment options.

Can AMICLINE be taken with other medications?

While specific drug-drug interactions for AMICLINE (Diloxanide Furoate) are not extensively detailed, it is crucial to inform your doctor about all other medications, including over-the-counter drugs, herbal products, and supplements you are currently taking. This helps to avoid any potential interactions.

What precautions should be taken while on AMICLINE?

It is important to avoid consuming alcohol while taking AMICLINE. Patients with pre-existing conditions such as liver disease, kidney problems, epilepsy, or multiple sclerosis should use this medicine with caution and inform their doctor. Drink plenty of fluids to stay hydrated during treatment, and ensure good hygiene to prevent the spread of infection. It is important to complete the full course of medication, even if symptoms improve, to ensure the infection is completely cleared. AMICLINE is not recommended for children below 2 years of age.

What happens if a dose of AMICLINE is missed?

If you miss a dose of AMICLINE, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should AMICLINE be stored?

AMICLINE tablets should be stored at room temperature, ideally between 20-25°C. Keep the medicine in its original container, away from moisture, direct light, and heat. Ensure it is kept out of reach of children and pets.