Ulyses Sr 600

ULYSES SR 600

Name:

• Brand Name: Ulyses SR 600 Tablet
• Common Name (Active Ingredient): Ursodeoxycholic Acid (UDCA)

Composition: Each tablet contains Ursodeoxycholic Acid (UDCA) 600 mg.

Uses: Ulyses SR 600 Tablet is primarily used for the treatment of various liver and gallbladder disorders. Its key uses include:

• Dissolving cholesterol gallstones and preventing their formation.
• Treatment of primary biliary cirrhosis (PBC), an autoimmune disease of the liver.
• Management of liver disorders in cystic fibrosis, especially in children above 6 years.
• Protecting liver cells from damage and improving overall liver function.
• Reducing cholesterol production in bile and promoting cholesterol solubility in bile.
• Treatment of bile duct inflammation and primary sclerosing cholangitis.

Dosage and Administration: Ulyses SR 600 Tablet should be taken as prescribed by your doctor. The dosage may vary based on body weight and the specific condition being treated.

• It should be swallowed whole with a glass of milk or water after a meal, preferably with your evening meal. Do not chew, crush, or break the tablet.
• Take it regularly for the prescribed duration, which can be several months or longer, even if symptoms disappear.

Side Effects: Most side effects are temporary and usually resolve upon discontinuing the medication. Common side effects may include:

• Abdominal discomfort/pain
• Diarrhoea
• Nausea and Vomiting
• Rash and Itching
• Hair loss (temporary thinning)
• Indigestion and Weakness
• Dizziness
• Sticky stool

If any serious side effects occur or if common side effects persist or worsen, consult your doctor.

Precautions:

• Allergies: Inform your doctor if you have known allergies to Ursodeoxycholic Acid or any other ingredients in the tablet.
• Pregnancy and Breastfeeding: Caution is advised. It should be used during pregnancy or breastfeeding only if prescribed by a doctor, as there is limited information on its safety. Women of childbearing age should use non-hormonal contraceptive measures or low estrogen oral contraceptive pills.
• Liver and Kidney Conditions: Ulyses SR 600 is used to manage certain liver conditions, but caution is needed in patients with active gallbladder inflammation, complete bile duct blockage, severe liver disease, or certain types of liver conditions. Regular monitoring of liver function tests may be required. Limited information is available for kidney disease; consult your doctor.
• Drug Interactions: Inform your doctor about all other medications you are taking, as Ulyses SR 600 can interact with:
  • Bile acid sequestrants (e.g., cholestyramine, colesevelam) – these can reduce absorption; maintain a gap of at least 4 hours.
  • Antacids (e.g., magaldrate) – may decrease effectiveness; avoid simultaneous use.
  • Hormone medicines (e.g., allylestrenol, oral contraceptives, estrogenic hormones) – may require dose adjustments or should be discontinued.
  • Lipid-lowering medicines (e.g., bezafibrate, atorvastatin) – generally not recommended for concurrent use.
  • Antibiotics (e.g., Ciprofloxacin) and immunosuppressants (e.g., Cyclosporine).
• Contraindications: Do not take if you have stomach or intestinal ulcers or bleeding, a non-functional gallbladder, inflammation or blockage of the gallbladder/biliary tract, or have recently had surgery involving any part of your intestine.
• Lifestyle: Avoid a high cholesterol diet during treatment, as it may affect effectiveness.
• Overdose: The most common symptom of overdose is diarrhea. Seek medical attention if you suspect an overdose.

Storage:

• Store the medication at temperatures not exceeding 25°C or below 30°C.
• Keep away from direct sunlight, heat, and moisture.
• Store in the original packaging to protect from environmental exposure.
• Keep out of reach of children and pets.
• Do not use after the expiry date printed on the package.

Here are frequently asked questions about ULYSES SR 600 by Lupin Ltd:

What is ULYSES SR 600 used for?

ULYSES SR 600 is primarily used to dissolve certain types of gallstones, particularly cholesterol gallstones. It is also prescribed for the treatment of primary biliary cirrhosis (an autoimmune liver disease) and to manage liver disorders associated with cystic fibrosis in children over 6 years of age.

How does ULYSES SR 600 work?

ULYSES SR 600 contains Ursodeoxycholic Acid (UDCA), which is a naturally occurring bile acid. It works by decreasing the production of cholesterol by the liver and making cholesterol more soluble in bile, thereby helping to dissolve existing cholesterol gallstones. Additionally, it protects liver cells from damage caused by toxic bile acids and improves overall liver function.

What is the usual dosage of ULYSES SR 600?

The dosage of ULYSES SR 600 is determined by your doctor based on your medical condition and body weight. The tablet should be swallowed whole with a glass of milk or water after a meal, and should not be chewed, crushed, or broken. It needs to be taken regularly for several months or longer as prescribed, even if symptoms disappear.

What are the possible side effects of ULYSES SR 600?

Common side effects may include abdominal pain or discomfort, diarrhea, nausea, rash, itching, dizziness, indigestion, weakness, and hair loss. Most of these side effects are temporary and usually resolve over time. If they persist or worsen, it is advised to consult your doctor.

Is ULYSES SR 600 safe during pregnancy or breastfeeding?

ULYSES SR 600 may be unsafe during pregnancy. Limited human studies exist, but animal studies have shown harmful effects on the developing baby. Therefore, it should only be used if prescribed by a doctor who has weighed the benefits against potential risks. Caution is advised during breastfeeding as the safety of ULYSES SR 600 in breastfeeding women is not fully established. Consult your doctor before using it.

Can ULYSES SR 600 be taken with other medications?

ULYSES SR 600 can interact with several medications. It is important to inform your doctor about all other medicines you are taking. Avoid taking antacids (like magaldrate) and bile acid sequestrants (like cholestyramine or colestipol) simultaneously, as they can reduce the effectiveness of ULYSES SR 600; a gap of at least 4 hours should be maintained. Oral contraceptives, estrogenic hormones, and certain cholesterol-lowering agents (like clofibrate) should also be avoided as they may increase the chances of gallstone formation. It may also interact with antibiotics (like ciprofloxacin) and antihypertensive agents (like nitrendipine), potentially enhancing their effects.

What precautions should be taken while using ULYSES SR 600?

Inform your doctor before taking ULYSES SR 600 if you have allergies to its components, gallbladder or bile duct inflammation, frequent upper abdominal pain, coughing up blood, rapid weight gain, variceal bleeding, excess abdominal fluid (ascites), liver encephalopathy, or any liver or kidney disease. Alcohol consumption should be avoided as it can lead to increased drowsiness and liver damage. Women of childbearing age should use non-hormonal contraceptive measures or low estrogen oral contraceptive pills. Do not stop taking the medication without consulting your doctor. Your doctor may monitor your liver function and bilirubin levels regularly during treatment.

What happens if a dose of ULYSES SR 600 is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should ULYSES SR 600 be stored?

ULYSES SR 600 should be stored in a cool and dry place, preferably below 30°C, away from direct sunlight, moisture, and heat. Keep the medication in its original packaging and out of the sight and reach of children and pets.