Vidaglo M 50/500 Mg Tablet (10 Tab)

VIDAGLO M 50/500 MG TABLET

VIDAGLO M 50/500 MG TABLET is an oral antidiabetic medication manufactured by Medley Pharmaceuticals Ltd.

• Composition: Each tablet contains Vildagliptin 50 mg and Metformin Hydrochloride 500 mg.

• Uses: This medicine is prescribed for the management of type 2 diabetes mellitus in adult patients. It is used when diet and exercise alone, or with other antidiabetic medicines, are insufficient to control blood sugar levels. VIDAGLO M helps to improve blood sugar control by enhancing insulin secretion, decreasing glucagon production, reducing glucose production in the liver, and improving the body's sensitivity to insulin. This action helps prevent serious diabetes-related complications such as kidney damage, nerve damage, eye problems, heart attack, and stroke.

• Dosage and Administration: VIDAGLO M 50/500 MG TABLET is typically taken orally once or twice daily, as prescribed by a doctor, usually with meals to reduce stomach upset. The tablet should be swallowed whole with water and not crushed, chewed, or broken.

• Side Effects:

  • Common: Nausea, vomiting, diarrhea, stomach pain/upset, headache, dizziness, low blood sugar (hypoglycemia characterized by dizziness, sweating, hunger pangs), loss of appetite, metallic taste, joint pain, and tiredness.
  • Serious (seek immediate medical attention): Symptoms of lactic acidosis (e.g., severe tiredness, muscle cramps, difficulty breathing, decreased heartbeat, severe stomach pain), or signs of an inflamed pancreas (severe, persistent abdominal pain with or without nausea/vomiting).

• Precautions:

  • Not recommended for patients with type 1 diabetes, severe kidney or liver disease, diabetic ketoacidosis, or congestive heart failure.
  • Use with caution in elderly patients.
  • Avoid alcohol consumption as it may increase the risk of lactic acidosis.
  • Pregnant or breastfeeding women should consult a doctor before use, as it is generally not recommended.
  • Inform your doctor if you have a history of pancreatitis or low vitamin B12 levels.
  • Regular monitoring of blood sugar levels, kidney function, and liver enzymes is essential.

• Storage: Store in a cool and dry place, protected from direct sunlight, and out of the reach of children.

What is VIDAGLO M 50/500 MG TABLET used for?

VIDAGLO M 50/500 MG TABLET is primarily used to manage Type 2 diabetes mellitus in adults. It helps control high blood sugar levels, especially when diet and exercise alone, or other single medications like vildagliptin or metformin, are not sufficient. This medication also plays a role in reducing the risk of long-term diabetes-related complications, such as kidney damage, blindness, heart attack, and stroke.

How does VIDAGLO M 50/500 MG TABLET work?

This medicine is a combination of two active ingredients: Vildagliptin (50 mg) and Metformin (500 mg).

• Vildagliptin works by inhibiting an enzyme called dipeptidyl peptidase-4 (DPP-4). This inhibition increases the levels of natural substances called incretin hormones (like GLP-1 and GIP), which help stimulate insulin release from the pancreas and decrease glucagon production in a glucose-dependent manner.
• Metformin belongs to the biguanide class. It primarily reduces glucose production in the liver, delays glucose absorption from the intestines, and improves the body's sensitivity to insulin, enhancing the uptake and utilization of glucose by tissues such as muscles. Together, these components work to improve insulin sensitivity, reduce glucose produced by the liver, and enhance glucose-dependent insulin secretion, thereby managing blood sugar levels.

What is the usual dosage for VIDAGLO M 50/500 MG TABLET?

The dosage of VIDAGLO M 50/500 MG TABLET should always be taken exactly as prescribed by your doctor. It is typically taken once or twice daily, usually with or after meals to help reduce stomach upset. The specific dose may vary based on your individual condition, blood sugar levels, and how you respond to the treatment. The tablets should be swallowed whole with a glass of water and should not be crushed, chewed, or broken.

What are the possible side effects of VIDAGLO M 50/500 MG TABLET?

Common side effects include diarrhea, nausea, vomiting, abdominal or stomach pain, loss of appetite, headache, dizziness, and nasopharyngitis (cold symptoms). Low blood sugar (hypoglycemia) can also occur, especially if taken with other diabetes medications like insulin or sulfonylureas. Serious but rare side effects include lactic acidosis (symptoms may involve vomiting, stomach pain, decreased heartbeat, difficulty breathing, muscle cramps, severe tiredness, or reduced body temperature) and inflammation of the pancreas (severe and persistent abdominal pain). If you experience any severe or persistent side effects, you should consult your doctor immediately.

Is VIDAGLO M 50/500 MG TABLET safe during pregnancy or breastfeeding?

Pregnancy: Caution is advised when taking VIDAGLO M 50/500 MG TABLET during pregnancy. It is generally not recommended unless specifically advised by your doctor after a careful assessment of potential risks and benefits, as there is limited information regarding its safety in pregnant women. Breastfeeding: This medicine is generally not recommended for breastfeeding women, as its components are known to pass into breast milk, and it is considered probably unsafe. You should consult your doctor before using this medication if you are breastfeeding.

Can VIDAGLO M 50/500 MG TABLET be taken with other medications?

VIDAGLO M 50/500 MG TABLET can interact with various other medications. It is crucial to inform your doctor about all the medicines, supplements, or herbal products you are currently taking or plan to take to avoid potential interactions. Some medications that may interact include cationic medications (e.g., amiloride, digoxin, trimethoprim), iodinated contrast agents (used in certain medical imaging procedures), CYP3A4 inducers (e.g., rifampicin), glucocorticoids, beta-2 agonists, diuretics, NSAIDs (e.g., ibuprofen), ACE inhibitors, ranolazine, tranylcypromine, acetazolamide, amiodarone, betamethasone, thyroid hormones, and antacids like cimetidine.

What precautions should be taken while using VIDAGLO M 50/500 MG TABLET?

Avoid excessive alcohol consumption while taking this medication, as it can increase the risk of a serious condition called lactic acidosis. This medicine is not suitable for individuals with Type 1 diabetes, diabetic ketoacidosis, or severe kidney or liver disease. Use with caution if you have mild to moderate kidney or liver problems, heart conditions, pancreatitis, or a low vitamin B12 level. Regular monitoring of blood sugar levels, kidney function, and liver enzymes is essential during treatment. If you are scheduled for surgery, inform your doctor as you may need to temporarily stop this medication. Since it can cause dizziness, exercise caution when driving or operating machinery until you understand how the medication affects you. It is not recommended for children under 18 and should be used with caution in elderly patients (65 years and above). Do not stop taking the medication abruptly without consulting your doctor, and continue to follow your recommended diet and exercise program. It's advisable to carry a form of sugar with you to manage any episodes of low blood sugar.

What happens if a dose of VIDAGLO M 50/500 MG TABLET is missed?

If you miss a dose of VIDAGLO M 50/500 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should VIDAGLO M 50/500 MG TABLET be stored?

VIDAGLO M 50/500 MG TABLET should be stored in a cool, dry place, protected from direct sunlight, moisture, and heat. The storage temperature should preferably be below 30°C. It is crucial to keep this medication out of the sight and reach of children and pets.