Gr 8 Capsule

GR 8 CAPSULE

GR 8 Capsule, manufactured by FRANCO-INDIAN PHARMACEUTICALS PVT. LTD., is a prescription medicine used to manage various gastrointestinal conditions related to acidity and digestive motility.

Composition

GR 8 Capsule is a combination of two active ingredients:

• Omeprazole (20 mg): A proton pump inhibitor (PPI) that works by reducing the amount of acid produced in the stomach.
• Domperidone (10 mg): A prokinetic agent that increases the movements and contractions of stomach muscles, facilitating faster gastric emptying and preventing nausea and vomiting.

Uses

This medicine is primarily used to treat:

• Gastroesophageal Reflux Disease (GERD), also known as acid reflux.
• Heartburn and indigestion.
• Epigastric pain.
• Peptic ulcers.
• Zollinger-Ellison syndrome.

It helps in relieving symptoms such as heartburn, stomach pain, irritation, difficulty swallowing, nausea, and vomiting.

Dosage and Administration

GR 8 Capsule should be taken as advised by your doctor. It is typically taken without food, preferably 30 to 60 minutes or one hour before a meal, usually in the morning. The capsule should be swallowed whole with a glass of water and not crushed or chewed. The dosage and duration of treatment depend on your medical condition and response to the medicine.

Side Effects

Common side effects include:

• Dry mouth
• Stomach pain
• Diarrhea
• Headache
• Flatulence (gas)
• Dizziness

Less common or serious side effects (consult your doctor if persistent or severe) may include:

• Swelling of the face, lips, eyelids, tongue, hands, and feet
• Difficulty in breathing
• Skin rash
• Disrupted menstrual cycle
• Breast pain and tenderness
• Decreased sexual urge
• Drowsiness
• Fundic gland polyps (with long-term use)

Precautions

• Allergy: Do not take GR 8 Capsule if you are allergic to domperidone, omeprazole, or any other components of the medicine.
• Pregnancy and Breastfeeding: Consult your doctor before using this medicine if you are pregnant or breastfeeding, as caution is advised.
• Liver and Kidney Disease: Use with caution in patients with liver or kidney problems. Dose adjustment or an alternative treatment may be required, and it is not recommended for moderate to severe liver disease.
• Alcohol: Avoid consuming alcohol as it may increase drowsiness and stomach acid production.
• Driving: This medicine may cause sleepiness or dizziness, so avoid driving or operating heavy machinery if you are not alert.
• Children: Not generally recommended for children as safety and effectiveness have not been established.
• Drug Interactions: Inform your doctor about all other medicines, supplements, or herbal products you are taking, especially antiarrhythmics, antipsychotics, HIV protease inhibitors, and macrolide antibiotics, as interactions can occur.
• Other Conditions: Exercise caution if you have a history of gastrointestinal bleeding, intestinal obstruction, osteoporosis, pituitary gland tumors, prolonged QT interval, or heart diseases. Long-term use may increase the risk of bone fractures and mineral deficiencies like magnesium.

Storage

Store GR 8 Capsule in a cool and dry place, below 30°C, protected from direct sunlight, moisture, and heat. Keep it out of reach and sight of children and pets.

What is GR 8 Capsule used for?

GR 8 Capsule is a combination medicine used to treat conditions related to excess stomach acid. It is prescribed for heartburn, indigestion, epigastric pain, gastro-oesophageal reflux disease (GERD), peptic ulcers, and Zollinger-Ellison syndrome. It can also help manage symptoms like nausea, vomiting, bloating, burping, and acidity.

How does GR 8 Capsule work?

GR 8 Capsule contains two active ingredients: Omeprazole (a proton pump inhibitor) and Domperidone (a dopamine antagonist). Omeprazole works by blocking an enzyme in the stomach responsible for acid production, thus reducing the amount of acid. Domperidone increases the movements and contractions of stomach muscles, helping food move more easily through the digestive tract and preventing nausea and vomiting.

What is the usual dosage and how should it be taken?

GR 8 Capsule should be taken as directed by your doctor, usually 30-60 minutes or 15-30 minutes prior to food, preferably in the morning, on an empty stomach. The capsule should be swallowed whole with a glass of water and not crushed or chewed. The dose and duration of treatment will depend on your medical condition and response to the medicine.

What are the possible side effects of GR 8 Capsule?

Common side effects may include dry mouth, stomach pain, diarrhea, headache, and flatulence. Other less common side effects can include dizziness, sleepiness, disrupted menstrual cycle, and breast pain. If these side effects persist or worsen, it is advisable to consult your doctor.

Is GR 8 Capsule safe during pregnancy or breastfeeding?

GR 8 Capsule should be used with caution during pregnancy, and only if considered necessary by a physician, as there is limited safety information available. It may pass into breast milk, so it is important to consult your doctor before taking this medicine if you are breastfeeding; your doctor will prescribe it only if the benefits outweigh the risks.

Can GR 8 Capsule be taken with other medications?

GR 8 Capsule can interact with several other medications. It is crucial to inform your doctor about all current medications, including herbs and supplements, to prevent potential interactions. You should avoid taking GR 8 Capsule with anti-HIV medicine like nelfinavir. Caution is also advised with certain antiarrhythmics, antipsychotics, CYP3A4 inhibitors, and medicines whose absorption is dependent on stomach acid.

What precautions should be taken?

Before taking GR 8 Capsule, inform your doctor if you have any liver, kidney, or heart problems, gastrointestinal bleeding, intestinal obstruction or perforation, weak bones (osteoporosis), or a pituitary gland tumor. It is not recommended for children as safety has not been established. Avoid consuming alcohol, as it can increase drowsiness and stomach acid production. It may cause sleepiness or dizziness, so drive or operate machinery only if you are alert.

What happens if a dose is missed?

If you miss a dose of GR 8 Capsule, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing routine. Do not take a double dose to make up for the missed one.

How should it be stored?

GR 8 Capsule should be stored in a cool and dry place, protected from direct sunlight, moisture, and heat. Keep it in its original container and out of the sight and reach of children. Always ensure to use the medicine before its expiry date.