Lupisulin M 30/70 Injection 40 Iu 10 Ml (vial)

LUPISULIN M 30/70 INJECTION 40 IU 10 ML (VIAL)

LUPISULIN M 30/70 INJECTION is a premixed insulin formulation by LUPIN LTD..

• Name:

  • Brand Name: LUPISULIN M 30/70
  • Common Name: Biphasic Isophane Insulin (a combination of human insulin and isophane insulin).

• Composition: LUPISULIN M 30/70 contains a combination of two types of human insulin:

  • 30% Soluble Insulin (rapid-acting)
  • 70% Isophane Insulin (intermediate-acting) Each 10 ml vial contains 40 International Units (IU) of insulin per milliliter. It also contains metacresol and phenol as preservatives.

• Uses: This medication is prescribed for the management of diabetes mellitus (both Type 1 and Type 2) in adults and children who require insulin therapy. It helps to control high blood sugar levels by facilitating glucose uptake by cells and inhibiting glucose production by the liver, providing both mealtime and basal insulin coverage. It can also be used to treat diabetes during pregnancy if recommended by a doctor.

• Dosage and Administration: LUPISULIN M 30/70 is administered via subcutaneous injection, typically 30 minutes before a meal. The dosage is highly individualized and determined by a healthcare professional based on blood sugar levels, diet, activity, and other medications. Injection sites should be rotated (e.g., abdomen, thigh, upper arm, or buttocks) to prevent lipodystrophy (thickening or pitting of the skin).

• Side Effects: Common side effects include:

  • Low blood sugar (hypoglycemia), characterized by symptoms like lightheadedness, dizziness, anxiety, sweating, shaking, and hunger.
  • Injection site reactions such as pain, redness, itching, swelling, or thickening of the skin.
  • Weight gain.
  • Peripheral edema (swelling in the limbs).
  • Visual disturbances.

• Precautions:

  • Regular blood sugar monitoring is essential to adjust the dosage as needed.
  • Avoid consuming alcohol, as it can interfere with insulin's effectiveness and affect blood glucose levels.
  • Exercise caution when driving or operating machinery, as insulin can cause low blood sugar levels, potentially impairing ability.
  • Patients with liver, kidney, or heart problems should use this medicine with caution and under medical supervision.
  • Do not stop taking the medicine without consulting a doctor, as it can lead to high blood sugar levels.
  • Always carry a source of sugar (e.g., glucose tablets or sugary snacks) to treat episodes of low blood sugar.

• Storage: Unopened vials of LUPISULIN M 30/70 should be stored in a refrigerator at 2°C to 8°C (36°F to 46°F). Do not freeze the medicine. After the first use, the medicine can be stored at room temperature (below 30°C) for up to 28 days. Keep it out of reach of children and away from direct light.

Here are frequently asked questions about LUPISULIN M 30/70 INJECTION 40 IU 10 ML (VIAL):

What is LUPISULIN M 30/70 INJECTION used for?

LUPISULIN M 30/70 INJECTION is an antidiabetic medication used to improve glycemic control in patients with diabetes mellitus, including both Type 1 and Type 2 diabetes. It helps regulate blood sugar levels, especially after meals, and provides basal insulin support.

How does LUPISULIN M 30/70 INJECTION work?

LUPISULIN M 30/70 INJECTION contains Biphasic Isophane Insulin, a pre-mixed combination of 30% rapid-acting (soluble) insulin and 70% intermediate-acting (isophane NPH) insulin. The rapid-acting component quickly lowers blood sugar levels by facilitating the uptake of glucose into muscle and fat tissues and suppressing glucose production by the liver. The intermediate-acting component provides a longer-lasting effect to control blood sugar levels between meals and overnight.

What is the usual dosage for LUPISULIN M 30/70 INJECTION?

The dosage of LUPISULIN M 30/70 INJECTION is highly individualized and determined by a healthcare professional based on factors such as blood glucose levels, diet, activity level, and other medications. It is typically administered subcutaneously (under the skin) into the thighs, buttocks, upper arm, or abdomen, usually 15-30 minutes before a meal. It should not be administered directly into a vein or muscle.

What are the possible side effects of LUPISULIN M 30/70 INJECTION?

The most common side effect is hypoglycemia (low blood sugar levels), which can manifest as sweating, shaking, anxiety, blurred vision, rapid heartbeat, dizziness, headache, hunger, confusion, and irritability. Other common side effects include injection site reactions such as pain, redness, itching, swelling, or thickening of the skin (lipodystrophy), and weight gain. Consult your doctor if any side effects trouble you.

Is LUPISULIN M 30/70 INJECTION safe during pregnancy or breastfeeding?

LUPISULIN M 30/70 INJECTION can be used during pregnancy if prescribed by a physician, though close monitoring of blood sugar levels is advised as dose requirements may change. It is generally considered safe for use during breastfeeding. Always consult your doctor before using this medicine if you are pregnant or breastfeeding.

Can LUPISULIN M 30/70 INJECTION be taken with other medications?

Before starting LUPISULIN M 30/70 INJECTION, inform your doctor about all other medicines you are taking, including over-the-counter drugs and supplements, as interactions can occur. Certain medications, such as other antidiabetic agents, corticosteroids, and thyroid hormones, may require insulin dose adjustments. Some medicines may also mask the symptoms of low blood sugar.

What precautions should be taken while using LUPISULIN M 30/70 INJECTION?

It is crucial to rotate injection sites to prevent skin damage like lipodystrophy. Do not stop therapy without consulting your doctor, as this can lead to high blood sugar levels. Exercise caution if you have kidney, liver, or heart problems, or hormonal issues, and inform your doctor about any sudden changes to your diet or intense exercise. Avoid alcohol consumption as it can affect blood glucose levels. Do not drive or operate heavy machinery if your ability is affected by low blood sugar.

What happens if a dose of LUPISULIN M 30/70 INJECTION is missed?

Missing a dose can lead to high blood sugar levels (hyperglycemia). If you miss a dose, check your blood sugar level as soon as you remember. Based on the reading, you can then take the next dose as prescribed. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Never take a double dose to compensate, as this can cause a drastic and dangerous fall in blood glucose. Always consult your doctor for guidance.

How should LUPISULIN M 30/70 INJECTION be stored?

Unopened vials of LUPISULIN M 30/70 INJECTION should be stored in a refrigerator between 2°C and 8°C (36°F to 46°F). Do not freeze the medicine, and protect it from light by keeping it in its carton. After first use, the medicine can typically be stored at room temperature (below 30°C) for up to 28 days. Keep it out of reach of children.