O2h Tablet (10 Tab)

O2H Tablet (10 Tab) by MEDLEY PHARMACEUTICALS LTD.

O2H Tablet is a combination antibiotic medication designed to treat a wide range of bacterial and parasitic infections. It is manufactured by Medley Pharmaceuticals Ltd..

• Composition O2H Tablet contains Ofloxacin (100 mg) and Ornidazole (250 mg) as active ingredients.

• Uses This medication is prescribed for various bacterial and parasitic infections, including those affecting the urinary tract, respiratory tract (e.g., bronchitis, pneumonia), skin and soft tissues, eyes and ears, and sexually transmitted infections. It is also effective in treating gastrointestinal infections such as infectious diarrhea and dysentery, intra-abdominal infections, protozoan infections, and for prophylaxis during surgical procedures.

• Dosage and Administration O2H Tablet is typically taken orally, usually once or twice daily, or as directed by a physician. It can be consumed with or without food, though taking it with food may help reduce stomach discomfort. The tablet should be swallowed whole with water and not crushed, chewed, or broken. It is crucial to complete the full course of treatment as prescribed, even if symptoms improve, to ensure complete eradication of the infection.

• Side Effects Common side effects may include nausea, vomiting, abdominal pain, headache, dizziness, insomnia, itching, and vaginal inflammation. These usually resolve over time, but a doctor should be consulted if they persist or worsen. More serious, though less common, side effects can include photosensitivity, tendonitis or tendon rupture, hallucinations, and seizures.

• Precautions Before taking O2H Tablet, inform your doctor about any history of allergies to its ingredients (Ofloxacin or Ornidazole) or to quinolone/nitroimidazole antibiotics. Caution is advised for patients with existing conditions such as epilepsy, diabetes, heart, kidney, or liver problems, nervous or muscle disorders, head injury, or myasthenia gravis. It is generally not recommended during pregnancy or breastfeeding; consult your doctor. Alcohol consumption should be avoided as it may enhance dizziness. Due to potential dizziness and drowsiness, avoid driving or operating heavy machinery until you understand how the medicine affects you.

• Storage Store O2H Tablet in a cool, dry place away from direct sunlight and moisture. Keep it out of sight and reach of children. The recommended storage temperature is typically between 10ºC to 25ºC or below 30ºC.

Here are frequently asked questions about O2H Tablet (10 TAB) by MEDLEY PHARMACEUTICALS LTD.:

What is O2H Tablet used for?

O2H Tablet is a combination medication primarily prescribed to treat various bacterial and parasitic infections. It is commonly used for infectious diarrhea and dysentery, as well as other infections affecting the gastrointestinal tract, urinary tract, respiratory tract (e.g., bronchitis, pneumonia), skin and soft tissues, eyes, ears, and reproductive system. It can also be used for intra-abdominal infections and as a prophylactic measure during certain surgical procedures.

How does O2H Tablet work?

O2H Tablet contains two active ingredients: Ofloxacin and Ornidazole. Ofloxacin is an antibacterial agent that works by inhibiting bacterial DNA gyrase, an enzyme crucial for bacterial DNA replication, transcription, repair, and recombination, ultimately leading to bacterial cell death. Ornidazole is an antiamoebic and antibacterial agent that kills parasites and anaerobic bacteria by damaging their DNA and other vital biomolecules through the formation of reactive nitro radicals, and by inhibiting protein synthesis. Together, these components provide a dual mechanism to effectively combat a broad spectrum of infections.

What is the usual dosage for O2H Tablet?

The usual adult dosage for O2H Tablet is generally one tablet taken twice daily, or as prescribed by your doctor. It is recommended to take the tablet with food at a fixed time each day to help minimize stomach upset and ensure better efficacy. It is crucial to complete the entire course of treatment as prescribed by your doctor, even if your symptoms improve earlier, to prevent the infection from returning and to avoid antibiotic resistance.

What are the possible side effects of O2H Tablet?

Common side effects of O2H Tablet can include nausea, vomiting, stomach pain, dizziness, headache, difficulty sleeping (insomnia), itching, vaginal inflammation, and diarrhea. Some individuals may also experience tiredness, photosensitivity, or loss of appetite. If any side effects worsen or persist, or if you experience more severe reactions such as hallucinations, seizures, severe itching, allergic reactions (rashes, swelling, difficulty breathing), or tendon pain/swelling, you should seek immediate medical attention.

Is O2H Tablet safe during pregnancy or breastfeeding?

O2H Tablet is generally not recommended for use during pregnancy as it may be unsafe and animal studies have shown potential harmful effects on the developing baby. Similarly, it is contraindicated during breastfeeding as its components can pass into human breast milk and may harm the infant. Always consult your doctor for advice if you are pregnant, planning a pregnancy, or breastfeeding, as they will weigh the potential risks and benefits in specific situations.

Can O2H Tablet be taken with other medications?

O2H Tablet can interact with various other medications. It's important to inform your doctor about all current medications, including over-the-counter drugs, supplements, and herbal remedies. Some notable interactions include:

• Antacids (containing aluminum or magnesium), sucralfate, and cimetidine: May reduce absorption.
• Anticoagulants (e.g., warfarin): May increase the risk of bleeding.
• NSAIDs (e.g., ibuprofen, diclofenac): May increase the risk of seizures.
• Theophylline: May increase its levels in the body.
• Certain antipsychotics, antidepressants, antiarrhythmics, and corticosteroids. Your doctor will assess potential interactions and adjust your treatment plan accordingly.

What precautions should be taken while using O2H Tablet?

Several precautions should be observed when taking O2H Tablet:

• Medical Conditions: Inform your doctor if you have a history of liver or kidney disease, seizure disorders (e.g., epilepsy), central nervous system disorders, heart conditions (like QT prolongation or irregular heartbeat), myasthenia gravis, diabetes, rheumatoid arthritis, or tendon-related issues, as this medicine may worsen these conditions or require dosage adjustments.
• Alcohol: Avoid consuming alcohol as it can increase dizziness and drowsiness.
• Driving/Operating Machinery: This medicine may cause dizziness and drowsiness, so avoid driving or operating heavy machinery until you know how it affects you.
• Tendon Problems: Report any tendon pain, swelling, or inflammation immediately, as there's a risk of tendon rupture.
• Sunlight Exposure: The medicine may increase sensitivity to sunlight (photosensitivity).
• Children: It is generally not recommended for children under 16-18 years of age.

What happens if a dose of O2H Tablet is missed?

If you miss a dose of O2H Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should O2H Tablet be stored?

O2H Tablet should be stored in a cool and dry place, away from direct sunlight and moisture. The ideal storage temperature is typically between 10°C and 30°C (room temperature). Always keep the medicine out of the sight and reach of children.