Irban 5 Mg Tablet (10 Tab)

IRBAN 5 MG TABLET

IRBAN 5 MG TABLET, manufactured by Glenmark Pharmaceuticals Ltd., is a medication primarily used for managing specific heart conditions.

• Composition The active ingredient in IRBAN 5 MG TABLET is Ivabradine (5 mg). It belongs to a class of medicines known as hyperpolarization-activated cyclic nucleotide-gated (HCN) channel blockers, which work by selectively lowering the heart rate.

• Uses IRBAN 5 MG TABLET is prescribed for adults to treat:

  • Symptomatic stable angina pectoris: Heart-related chest pain, particularly in patients who cannot take beta-blockers.
  • Chronic heart failure: In adults with New York Heart Association (NYHA) class II-IV systolic dysfunction and a resting heart rate of 75 beats per minute or more. It helps the heart work more efficiently by reducing the heart rate, thereby decreasing the heart's workload and oxygen demand, which alleviates chest pain and reduces the risk of hospitalization for heart failure.

• Dosage and Administration

  • Adults: The typical starting dosage is 5 mg twice daily, taken with meals.
  • The dosage may be adjusted by a doctor up to a maximum of 7.5 mg twice daily, depending on the patient's response.
  • Swallow the tablet whole with water; do not chew, crush, or break it.
  • It is crucial to take the tablet regularly with food at the same time each day for consistent effects. Do not discontinue the medication without consulting your doctor, as treatment for these conditions is often long-term.

• Side Effects

  • Common: Temporary brightness in vision (luminous phenomena/phosphenes), slow heart rate (bradycardia), high blood pressure, atrial fibrillation, dizziness, blurred vision, headache, and ECG changes. Nausea, abdominal pain, and diarrhea have also been reported.
  • Serious: Fainting, significant changes in heartbeat (irregular or rapid heartbeat), or excessively slowed heart rate potentially leading to breathlessness or fatigue, which require urgent medical attention.

• Precautions

  • IRBAN 5 MG TABLET is contraindicated in individuals with severe liver disease, a low resting heart rate, certain heart rhythm disorders, very low blood pressure, or worsening heart failure.
  • It should not be used during pregnancy or breastfeeding, and generally not in children or adolescents under 18 years of age (with specific exceptions for heart failure in children over 6 months).
  • Exercise caution when driving or operating machinery, as the medication can cause dizziness or visual disturbances.
  • Interactions can occur with other heart rate-lowering medications (e.g., beta-blockers, certain calcium channel blockers) and drugs affecting CYP3A4 enzymes.
  • Regular monitoring of heart function and blood pressure is recommended during treatment.

• Storage Store IRBAN 5 MG TABLET at room temperature, typically below 25°C or 30°C, protected from moisture and heat. Keep it in its original packaging and out of the reach of children.

What is Irban 5mg Tablet used for?

Irban 5mg Tablet is primarily used to manage stable symptomatic angina pectoris (chest pain) in adult patients who cannot take beta-blockers. It is also prescribed for the management of chronic heart failure in adults, particularly those with New York Heart Association (NYHA) class II-IV systolic dysfunction and a heart rate of 75 bpm or more. Additionally, it can assist children aged six months and older with stable symptomatic heart failure due to dilated cardiomyopathy.

How does Irban 5mg Tablet work?

Irban 5mg Tablet contains Ivabradine, which works by selectively inhibiting the cardiac pacemaker current (If) in the heart's sinoatrial node, the natural pacemaker. This inhibition reduces the heart rate by a few beats per minute, thereby decreasing the heart's workload and oxygen requirements. This mechanism helps to manage symptoms of angina and improve outcomes in patients with heart failure.

What is the usual dosage of Irban 5mg Tablet?

The typical starting dosage for adults is 5 mg twice daily, taken with meals. Depending on the patient's response and heart rate, the dosage may be adjusted by a doctor, with a maximum recommended dose of 7.5 mg twice daily. It is crucial to take the tablet whole with water and at the same time each day for consistent results.

What are the possible side effects of Irban 5mg Tablet?

Common side effects include luminous phenomena (seeing temporary flashes or spots of light), blurred vision, a slower-than-normal heartbeat (bradycardia), headache, dizziness, and sometimes increased blood pressure. More serious side effects, though less common, can include fainting or significant alterations in heartbeat, such as atrial fibrillation. If you experience any severe or persistent side effects, you should consult your doctor.

Is Irban 5mg Tablet safe during pregnancy or breastfeeding?

Irban 5mg Tablet is generally not recommended during pregnancy unless clearly necessary, as its use can harm the unborn baby. Women who are capable of becoming pregnant should use effective birth control measures during treatment. It is also considered unsafe during breastfeeding, and breastfeeding women should avoid using this medication.

Can Irban 5mg Tablet be taken with other medications?

Irban 5mg Tablet can interact with several medications. It may enhance the effects of other heart rate-lowering medications like beta-blockers or calcium channel blockers. Strong CYP3A4 inhibitors (such as ketoconazole, ritonavir, clarithromycin) are contraindicated as they can significantly increase the exposure to Ivabradine, while CYP3A4 inducers (like rifampicin) can considerably decrease its effectiveness. Inform your doctor about all medicines, herbals, and supplements you are taking to avoid potential interactions.

What precautions should be taken while using Irban 5mg Tablet?

Precautions include avoiding Irban 5mg Tablet if you have severe liver disease, a very slow resting heart rate, or certain heart rhythm disorders. It should also be used with caution in patients with low blood pressure or severe kidney disease. The medication can cause dizziness or visual disturbances, so caution is advised when driving or operating heavy machinery until you know how it affects you. Regular monitoring of heart function and blood pressure by your doctor is recommended.

What happens if a dose of Irban 5mg Tablet is missed?

If you forget to take a dose of Irban 5mg Tablet, take it as soon as you remember. However, if it is nearly time for your next scheduled dose, skip the missed dose and continue with your regular schedule. Do not double the dose to compensate for a missed one.

How should Irban 5mg Tablet be stored?

Irban 5mg Tablet should be stored at room temperature, ideally below 25°C, and protected from humidity and moisture. Keep it in its original package and ensure it is kept out of the reach and sight of children and pets. Always check the expiration date and do not use the medicine beyond its usage period.