Macfast Plus

MACFAST PLUS

MACFAST PLUS is a medication manufactured by Macleods Pharmaceuticals Ltd., primarily used for pain relief and fever reduction. It is available as a syrup or suspension.

• Composition Each 5 ml of MACFAST PLUS suspension contains:

  • Acetaminophen (Paracetamol): 125 mg
  • Mefenamic Acid: 50 mg

• Uses MACFAST PLUS is prescribed for the relief of mild to moderate pain and reduction of fever. Its uses include:

  • Headaches, toothaches, ear pain, and muscle aches
  • Menstrual cramps (dysmenorrhea) and heavy bleeding during periods
  • Pain and inflammation associated with conditions like osteoarthritis, rheumatoid arthritis, and other inflammatory disorders
  • Pain after surgery
  • Fever and flu-like symptoms

• Dosage and Administration The recommended dosage should be determined by a healthcare provider, based on age and weight. It is typically administered orally. It can be taken with or without food, though taking it with food may help reduce stomach upset. Shake the bottle well before use and measure the appropriate dosage with a measuring spoon or syringe. Do not exceed the recommended dose.

• Side Effects Common side effects may include nausea, vomiting, stomach upset/pain, indigestion, heartburn, diarrhea, dizziness, and headache. Serious side effects, requiring immediate medical attention, include severe stomach pain, black or tarry stools, allergic reactions (hives, difficulty breathing, swelling of face/lips/tongue/throat), or signs of liver or kidney damage.

• Precautions Do not use MACFAST PLUS if you have a history of hypersensitivity or allergic reactions to acetaminophen or mefenamic acid. It is contraindicated in individuals with bleeding disorders, severe liver or kidney disease, stomach ulcers, or gastrointestinal bleeding. Avoid use during pregnancy and breastfeeding, as it may harm the fetus or nursing infant. Alcohol consumption should be avoided due to an increased risk of liver damage. Inform your doctor about all other medications, including over-the-counter drugs and herbal supplements, especially blood thinners (e.g., warfarin, heparin) or other NSAIDs, as interactions can occur. MACFAST PLUS may cause dizziness; therefore, caution is advised when driving or operating machinery.

• Storage Store MACFAST PLUS at room temperature (below 30°C or 10°C to 25°C), away from direct sunlight, heat, and moisture. Keep it out of reach of children. Do not freeze.

MACFAST PLUS is a medicine manufactured by Macleods Pharmaceuticals Ltd., typically available as a suspension. It contains a combination of two active ingredients: Mefenamic Acid (50 mg per 5 ml) and Paracetamol (Acetaminophen) (125 mg per 5 ml).

Here are some frequently asked questions about MACFAST PLUS:

What is MACFAST PLUS used for?

MACFAST PLUS is primarily used to relieve pain and reduce fever. It is effective for various types of pain, including headaches, migraines, nerve pain, toothaches, sore throats, menstrual pain (dysmenorrhea), muscle aches, joint pain, and pain following surgery. It also helps reduce inflammation.

How does MACFAST PLUS work?

MACFAST PLUS works through its two active ingredients. Paracetamol (Acetaminophen) acts as an analgesic (pain reliever) and antipyretic (fever reducer) by blocking the production of prostaglandins in the brain, which are chemicals responsible for pain and fever. Mefenamic Acid is a non-steroidal anti-inflammatory drug (NSAID) that reduces pain and inflammation by inhibiting the production of certain chemical messengers, like prostaglandins, involved in the body's inflammatory response.

What is the usual dosage for MACFAST PLUS?

The dosage for MACFAST PLUS suspension should always be as prescribed by a doctor, as it depends on the patient's age and weight. The medicine should be taken orally, and the bottle should be shaken well before use. It can be taken with or without food, but taking it after food may help prevent an upset stomach. It is crucial to follow the recommended dosage and not exceed it.

What are the possible side effects of MACFAST PLUS?

Common side effects may include nausea, vomiting, stomach upset, abdominal pain, heartburn, diarrhea, dizziness, lightheadedness, and headache. More serious side effects can include allergic reactions (such as hives, difficulty breathing, or swelling of the face, lips, tongue, or throat), severe stomach pain, black or tarry stools (indicating gastrointestinal bleeding), kidney damage, or liver damage, especially with high or prolonged doses. Seek immediate medical attention if you experience severe symptoms like black, tarry stools or significant allergic reactions.

Is MACFAST PLUS safe during pregnancy or breastfeeding?

There is conflicting information regarding the safety of MACFAST PLUS during pregnancy and breastfeeding. Some sources indicate it should not be used during pregnancy as it may harm the developing fetus and is not recommended during breastfeeding as it can pass into breast milk. Other sources suggest it may be unsafe during pregnancy and should be used only if considered necessary after consulting a doctor, and state it is safe during breastfeeding as significant amounts do not pass into breast milk. Due to these contradictions, it is essential to consult a doctor before using this medication if you are pregnant or breastfeeding.

Can MACFAST PLUS be taken with other medications?

MACFAST PLUS can interact with other medications. It is important to inform your doctor or pharmacist about all medications, supplements, and herbal remedies you are taking. Specific interactions include:

• Blood thinners (e.g., warfarin, heparin): Increased risk of bleeding.
• Other NSAIDs (e.g., aspirin, ibuprofen): Increased risk of stomach ulcers and bleeding.
• Antidepressants (e.g., fluoxetine, sertraline): Increased risk of bleeding.
• Anticonvulsants (e.g., phenytoin, carbamazepine): May decrease the effectiveness of acetaminophen.
• Other paracetamol-containing medicines: Avoid to prevent the risk of liver damage.
• Alcohol: Avoid consuming alcohol, as it can increase the risk of liver damage when taken with acetaminophen and may increase dizziness.

What precautions should be taken while using MACFAST PLUS?

Do not use MACFAST PLUS if you have a history of hypersensitivity or allergic reactions to acetaminophen or mefenamic acid. It is contraindicated in individuals with bleeding disorders, severe liver or kidney disease, stomach ulcers, or gastrointestinal bleeding. Inform your doctor about pre-existing conditions such as high blood pressure, heart problems, high cholesterol, asthma, or dehydration. Do not exceed the prescribed dosage or use the medicine for prolonged periods without medical supervision. If undergoing surgery, inform your doctor, as the medication might need to be withheld 3 to 5 days prior to prevent excessive bleeding.

What happens if a dose is missed?

If you miss a dose of MACFAST PLUS, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, and ensure a gap of at least 4-6 hours between doses.

How should MACFAST PLUS be stored?

Store MACFAST PLUS at room temperature, ideally below 30°C. Keep the medicine in a cool, dry place, away from direct sunlight, heat, and moisture. Ensure it is kept out of reach of children. Do not freeze the suspension.