Razel Cv 10/75 Mg Capsule (10 Cap)

RAZEL CV 10/75 MG CAPSULE

RAZEL CV 10/75 MG CAPSULE, manufactured by J.B. CHEMICALS & PHARMACEUTICALS LTD., is a combination medication designed for cardiovascular health management.

Composition

• Active Ingredients: Each capsule contains Rosuvastatin 10 mg and Clopidogrel 75 mg.

Uses

RAZEL CV 10/75 MG CAPSULE is primarily prescribed to:

• Lower "bad" cholesterol (LDL) and triglyceride levels while increasing "good" cholesterol (HDL).
• Prevent the formation of harmful blood clots.
• Reduce the risk of serious cardiovascular events such as heart attacks, strokes, and chest pain (angina).
• Manage conditions like atherosclerosis, high triglycerides, and peripheral vascular disease.

Dosage and Administration

• Typical Guidance: This medicine is usually taken once daily, preferably at the same time each day, with or without food.
• The capsule should be swallowed whole with a glass of water; do not crush, cut, or chew it.
• Adhere strictly to the dosage and duration prescribed by your healthcare provider.

Side Effects

• Common Side Effects: Headache, nausea, diarrhea, abdominal pain, muscle pain, dizziness, increased glucose levels, and increased liver enzymes.
• Serious Side Effects (less common): Allergic reactions (rash, itching, swelling), liver problems (yellowing of skin/eyes), rhabdomyolysis (muscle breakdown leading to kidney damage), pancreatitis, and an increased risk of bleeding. Consult your doctor if any side effects persist or worsen.

Precautions

• Pregnancy and Breastfeeding: RAZEL CV 10/75 MG CAPSULE is not recommended during pregnancy (Rosuvastatin is Pregnancy Category X) or breastfeeding, as it may harm the baby.
• Liver and Kidney Conditions: Use with caution in patients with kidney impairment, and it is generally considered unsafe for those with liver disease and should be avoided.
• Bleeding Risk: This medication increases the risk of bleeding; exercise caution with sharp objects or activities that may cause injury.
• Drug Interactions: Inform your doctor about all other medications, supplements, and herbal remedies being taken, especially NSAIDs, Cyclosporine, and Fibrates, as interactions can occur.
• Do not discontinue the medicine without consulting your doctor, as sudden cessation may increase the risk of heart attack or stroke. Regular monitoring of cholesterol levels and liver function is essential.

Storage

• Store at room temperature, ideally below 30°C.

RAZEL CV 10/75 MG CAPSULE contains Rosuvastatin (10mg) and Clopidogrel (75mg). This combination medication is primarily used to manage cholesterol levels and reduce the risk of cardiovascular events such as heart attack and stroke.

What is RAZEL CV 10/75 MG CAPSULE used for?

RAZEL CV 10/75 MG CAPSULE is used to prevent heart attacks, strokes, and chest pain (angina) in individuals at high risk of heart problems. It helps control high cholesterol by reducing "bad" cholesterol (LDL) and triglycerides while increasing "good" cholesterol (HDL). It also helps prevent blood clots from forming.

How does RAZEL CV 10/75 MG CAPSULE work?

This medicine combines two active ingredients: Rosuvastatin and Clopidogrel.

• Rosuvastatin is a statin that works by inhibiting an enzyme in the liver (HMG-CoA reductase) crucial for cholesterol production. This action lowers LDL (bad cholesterol) and triglycerides and increases HDL (good cholesterol).
• Clopidogrel is an antiplatelet medicine (blood thinner) that prevents platelets (blood cells) from clumping together and forming harmful blood clots. Together, they improve blood flow, reduce blockages, and lower the risk of heart attack and stroke.

What is the usual dosage?

RAZEL CV 10/75 MG CAPSULE is typically taken once daily, with or without food, as prescribed by your doctor. It is important to take it at the same time each day to ensure optimal effectiveness and adherence. Do not crush, chew, or break the capsule; swallow it whole with water. Your doctor will determine the appropriate dose and duration of treatment based on your medical condition.

What are the possible side effects?

Common side effects of Rosuvastatin + Clopidogrel may include headache, stomach pain, indigestion, heartburn, constipation, nausea, dizziness, and muscle pain. More serious, though rare, side effects can include muscle injury (myopathy, rhabdomyolysis), liver problems (increased liver enzymes, liver injury), and an increased risk of bleeding (e.g., nosebleeds, gastrointestinal bleeding). If you experience unexplained muscle pain, tenderness, or weakness, especially with fever or dark urine, contact your doctor immediately. Similarly, report any signs of liver problems like unusual tiredness, loss of appetite, upper belly pain, dark urine, or yellowing of the skin or eyes.

Is it safe during pregnancy or breastfeeding?

RAZEL CV 10/75 MG CAPSULE (containing Rosuvastatin and Clopidogrel) is generally not recommended during pregnancy. Rosuvastatin may cause fetal harm and is strictly contraindicated. If you become pregnant while taking this medicine, stop taking it and inform your doctor immediately.

For breastfeeding, Rosuvastatin is also generally not recommended, as it may pass into breast milk in small amounts and could have adverse effects on the infant. While Clopidogrel may be used with caution during breastfeeding under medical guidance, the combination is often advised against. Consult your doctor or pharmacist to discuss the benefits and risks if you are breastfeeding.

Can it be taken with other medications?

Taking RAZEL CV 10/75 MG CAPSULE with certain other medications can lead to interactions. Inform your doctor about all medications, supplements, and herbal products you are taking.

• Blood Thinners: Concomitant use with other blood thinners (like warfarin) or NSAIDs (like ibuprofen) can increase the risk of bleeding.
• Cyclosporine: Cyclosporine can significantly increase the levels of rosuvastatin in the blood, raising the risk of side effects. A lower dose of rosuvastatin may be necessary.
• Fibrates (e.g., Gemfibrozil): These medications can increase the risk of muscle damage when taken with rosuvastatin.
• Antacids: Antacids containing aluminum and magnesium hydroxide should be taken at least 2 hours after RAZEL CV 10/75 MG CAPSULE.
• Alcohol: Avoid or limit alcohol consumption as it can worsen liver conditions and increase liver enzyme secretion.

What precautions should be taken?

• Liver and Kidney Conditions: Inform your doctor if you have active liver disease, a history of liver problems, or severe kidney impairment, as the medication may be contraindicated or require dose adjustments.
• Bleeding Risk: Exercise caution if you have active bleeding issues (such as stomach ulcers or brain hemorrhage) or a history of bleeding disorders, as Clopidogrel increases the risk of bleeding.
• Muscle Problems: Be aware of the risk of muscle pain or weakness, and report any such symptoms to your doctor.
• Surgery: Always inform your doctor or dentist that you are taking this medicine before any surgery or medical procedure.
• Lifestyle: Maintain a healthy diet, exercise regularly, and avoid smoking to enhance the effectiveness of the medicine.

What happens if a dose is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.

How should it be stored?

Store RAZEL CV 10/75 MG CAPSULE in its original packaging, tightly closed, in a cool, dry place below 30°C. Protect it from moisture, heat, and direct sunlight. Keep the medicine out of reach of children and pets. Dispose of any unused or expired medication safely as per instructions or by taking it to a pharmacy.