Lipril 2.5 Mg Tablet (15 Tab)

LIPRIL 2.5 MG TABLET

LIPRIL 2.5 MG TABLET is a prescription medicine manufactured by Lupin Ltd., primarily used for managing cardiovascular conditions.

Composition

LIPRIL 2.5 MG TABLET contains Lisinopril 2.5 mg as its active ingredient. Lisinopril belongs to a class of medicines known as Angiotensin-Converting Enzyme (ACE) inhibitors, which work by relaxing and widening blood vessels, making it easier for the heart to pump blood more efficiently.

Uses

LIPRIL 2.5 MG TABLET is prescribed for several medical conditions:

• High Blood Pressure (Hypertension): It helps lower blood pressure, thereby reducing the risk of heart attack, stroke, and kidney problems.
• Heart Failure: It is used to manage heart failure, improving heart function and reducing symptoms like shortness of breath.
• Post-Heart Attack Management: It is administered to patients who have experienced a heart attack to aid recovery and prevent future cardiovascular events.
• Diabetic Kidney Disease: It helps protect kidneys from damage in patients with diabetes by reducing protein leakage in the urine.

Dosage and Administration

LIPRIL 2.5 MG TABLET should be taken orally at the same time each day, with or without food, as advised by your doctor. The first dose may cause dizziness, so your doctor might recommend taking it before bedtime. Subsequent doses can be taken at any time if dizziness is not experienced. Do not stop taking this medication without consulting your doctor, as it can worsen your condition. Do not double the dose to compensate for a missed one. Specific dosage varies based on the condition being treated and individual response.

Side Effects

Common side effects may include:

• Decreased blood pressure (hypotension)
• Headache
• Dizziness
• Dry cough
• Fatigue, weakness
• Nausea, vomiting, diarrhea
• Increased potassium levels in the blood
• Skin rash More serious, though less common, side effects can include blurred vision, confusion, decreased urine output, and chest discomfort.

Precautions

• Pregnancy and Breastfeeding: LIPRIL 2.5 MG TABLET is not recommended during pregnancy, especially after the third month, as it can cause harm to the developing baby. It is also probably unsafe for use during breastfeeding. Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.
• Alcohol Consumption: Avoid alcohol as it can enhance the blood pressure-lowering effect and cause excessive dizziness or fainting.
• Kidney and Liver Conditions: Use with caution in patients with kidney or liver diseases, as dose adjustments may be necessary, and regular monitoring of kidney function is advised.
• Potassium Levels: This medicine can increase blood potassium levels. Avoid potassium supplements and limit potassium-rich foods. Regular monitoring of potassium levels is recommended.
• Dizziness: Due to potential dizziness, especially initially, rise slowly from a sitting or lying position. Avoid driving or operating heavy machinery until you know how the medicine affects you.
• Drug Interactions: Inform your doctor about all other medications, supplements, or herbal products you are taking to prevent potential interactions, especially with diuretics, NSAIDs, antidiabetics, and other blood pressure medications.
• Allergies and Pre-existing Conditions: Inform your doctor if you have any allergies to lisinopril or its ingredients, or if you have a history of heart problems, diabetes, low white blood cell count, or recent vomiting/diarrhea.

Storage

Store LIPRIL 2.5 MG TABLET in a cool, dry place, protected from direct sunlight, moisture, and heat, ideally between 20°C to 25°C. Keep it out of reach of children and pets.

LIPRIL 2.5 MG TABLET, containing the active ingredient Lisinopril, is an angiotensin-converting enzyme (ACE) inhibitor commonly prescribed to manage various cardiovascular conditions.

What is LIPRIL 2.5 MG TABLET used for?

LIPRIL 2.5 MG TABLET is primarily used to treat high blood pressure (hypertension) in adults and children 6 years of age and older. It is also used as an adjunctive therapy for heart failure in adults and to reduce the risk of death after a heart attack. Additionally, it may be used off-label to treat kidney damage from diabetes.

How does LIPRIL 2.5 MG TABLET work?

LIPRIL 2.5 MG TABLET works by blocking the action of angiotensin-converting enzyme (ACE), an enzyme that converts angiotensin I to angiotensin II. Angiotensin II is a powerful vasoconstrictor, meaning it narrows blood vessels. By inhibiting its production, Lisinopril causes blood vessels to relax and widen, making it easier for blood to flow and reducing the workload on the heart. It also reduces the release of aldosterone, which helps the kidneys excrete sodium and water, further lowering blood pressure.

What is the usual dosage of LIPRIL 2.5 MG TABLET?

The dose of Lisinopril, including LIPRIL 2.5 MG TABLET, varies depending on the condition being treated and individual response. For high blood pressure, a typical starting dose in adults is 5 mg to 10 mg once per day, with the usual range being 20 mg to 40 mg once daily. For heart failure, the recommended starting dose is often 2.5 mg or 5 mg once daily. After a heart attack, the initial dose is typically 2.5 mg to 5 mg within 24 hours. Your doctor will determine the appropriate dosage for you and may adjust it as needed.

What are the possible side effects of LIPRIL 2.5 MG TABLET?

Common side effects of Lisinopril can include headache, dizziness, a dry and persistent cough, fatigue, nausea, diarrhea, and low blood pressure. More serious but less common side effects can include kidney problems (such as kidney failure), liver problems, high potassium levels (hyperkalemia), and angioedema (severe swelling of the face, lips, tongue, or throat). If you experience severe side effects, contact your doctor immediately.

Is LIPRIL 2.5 MG TABLET safe during pregnancy or breastfeeding?

No, LIPRIL 2.5 MG TABLET (Lisinopril) is not recommended during pregnancy, especially in the second and third trimesters, as it can cause harm to the unborn baby, including kidney problems, lung problems, skeletal changes, and potentially fetal death. If you become pregnant while taking this medication, stop taking it and contact your doctor immediately.

Regarding breastfeeding, manufacturers generally recommend against using lisinopril in breastfeeding women because the amount secreted in breast milk and its effects on the breastfed infant are unknown or it might be a small amount. Your doctor will help you decide if it's appropriate or may recommend an alternative.

Can LIPRIL 2.5 MG TABLET be taken with other medications?

LIPRIL 2.5 MG TABLET can interact with several other medications. It is important to inform your doctor about all medications, vitamins, herbs, and supplements you are taking. Significant interactions can occur with:

• Diuretics (water pills): May cause a severe drop in blood pressure.
• Potassium supplements or potassium-sparing diuretics: Can lead to dangerously high potassium levels in the blood (hyperkalemia).
• Nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen: Can reduce the blood pressure-lowering effect and increase the risk of kidney damage.
• Aliskiren or Angiotensin Receptor Blockers (ARBs): Should generally be avoided, especially in patients with diabetes or kidney problems, due to increased risk of low blood pressure, high potassium, and kidney damage.
• Sacubitril/valsartan (Entresto): Concomitant use is contraindicated due to a significantly increased risk of angioedema.
• Lithium: Lisinopril can increase lithium levels, leading to toxicity.

What precautions should be taken while taking LIPRIL 2.5 MG TABLET?

• Angioedema: There is a risk of severe allergic reaction causing swelling of the face, lips, tongue, or throat, which can be life-threatening. This risk may be higher in Black patients.
• Kidney and Liver Problems: Lisinopril should be used with caution in patients with kidney or liver impairment, and regular monitoring of kidney function and potassium levels may be necessary.
• Low Blood Pressure: Dizziness or lightheadedness can occur, especially when starting treatment or increasing the dose. This is more likely with dehydration, heavy sweating, vomiting, or diarrhea.
• Diabetes: Lisinopril may affect blood sugar levels, and monitoring may be required.
• Surgery: Inform your doctor or dentist you are taking Lisinopril before any surgery, including dental procedures.

What happens if a dose of LIPRIL 2.5 MG TABLET is missed?

If you miss a dose of LIPRIL 2.5 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this can increase the risk of side effects.

How should LIPRIL 2.5 MG TABLET be stored?

Store LIPRIL 2.5 MG TABLET at controlled room temperature, typically between 20°C and 25°C (68°F and 77°F). Protect the tablets from moisture, freezing, and excessive heat. Keep the container tightly closed and out of reach of children and pets. Dispose of any unused or expired medication properly.