Synaptol 50

SYNAPTOL 50

• Name: Synaptol 50 Tablet

• Manufacturer: Sun Pharmaceutical Industries Ltd.

• Composition:

  • Active Ingredient: Tolperisone 50mg

• Uses: Synaptol 50 is a centrally acting muscle relaxant used to alleviate various musculoskeletal conditions.

  • Acute Musculoskeletal Pain: Effective in managing pain originating from muscles, bones, or joints.
  • Muscle Spasms: Helps manage involuntary muscle contractions, improving comfort and movement.
  • Stiffness and Rigidity: Reduces tightness and restricted movement, enhancing flexibility.
  • Severe Back Pain: Beneficial in relieving discomfort associated with acute and chronic back pain.
  • Improved Muscle Function: Works by relaxing muscles, enhancing blood flow to the muscles, and reducing pain signaling, which promotes better muscle recovery and movement.
  • Neurological Conditions: May be prescribed for spasticity and muscle spasms associated with neurological disorders like multiple sclerosis and cerebral palsy.

• Dosage and Administration:

  • Always take Synaptol 50 as prescribed by your doctor.
  • It is recommended to take the tablet whole with a glass of water, without chewing, crushing, or breaking it.
  • Take Synaptol 50 with food to prevent an upset stomach and reduce the chance of side effects.
  • Typical Adult Dosage: 50-150 mg, three times a day, or as directed by a healthcare professional.
  • Children's Dosage:
    • Below 6 years: 5 mg/kg daily in 3 divided doses.
    • 6-14 years: 2-4 mg/kg daily in 3 divided doses.
  • Do not stop taking the medication abruptly without consulting your doctor, as it may lead to the return of symptoms or withdrawal effects.

• Side Effects:

  • Common Side Effects: Dizziness, sleepiness/drowsiness, weakness, fatigue, diarrhoea, sweating, abdominal pain/discomfort, nausea, vomiting, dry mouth, headache, indigestion, muscle weakness, and low blood pressure. These side effects are usually mild and may resolve over time.
  • Serious Side Effects (Hypersensitivity Reactions): Signs such as flushing, rash, wheezing, severe skin itching, difficulty breathing, swelling of the face, lips, tongue, or throat, difficulty swallowing, low blood pressure, fast heartbeat, or rapid decrease in blood pressure may occur. Seek immediate medical attention if any of these occur.

• Precautions:

  • Allergies: Inform your doctor if you have any known allergies, especially to Tolperisone or other ingredients in Synaptol 50.
  • Medical Conditions: Consult your doctor if you have myasthenia gravis (muscle weakness), asthma, hay fever, or severe liver or kidney disease.
  • Pregnancy and Breastfeeding: Use with caution during pregnancy and only if advised by a doctor, especially in the initial three months. It is generally not recommended for breastfeeding mothers as it may harm the newborn.
  • Children and Elderly: Use with caution in children and elderly patients; dosage adjustments and close monitoring may be necessary.
  • Driving and Operating Machinery: Synaptol 50 may cause dizziness or sleepiness. Avoid driving or engaging in activities requiring concentration until you know how the medicine affects you.
  • Alcohol Consumption: Avoid or limit alcohol consumption while taking this medication, as it may increase sedative effects and drowsiness.
  • Drug Interactions: Inform your doctor about all other medications, herbal preparations, and supplements you are taking. Interactions can occur with other muscle relaxants (e.g., Methocarbamol) and certain painkillers (e.g., NSAIDs).

• Storage:

  • Store in a cool and dry place, away from direct sunlight.
  • Keep out of sight and reach of children.
  • Maintain storage temperatures between 10ºC to 25ºC or below 30ºC.
  • Protect from light and moisture.
  • Ensure the medicine is kept in its original packaging.

What is Synaptol 50 Tablet used for?

Synaptol 50 Tablet, containing Tolperisone, is primarily used as a muscle relaxant to treat muscle spasms, rigidity, and stiffness. It is also prescribed for acute musculoskeletal pain, severe back pain, and can help manage conditions like post-cerebral stroke spasticity and trapezitis.

How does Synaptol 50 Tablet work?

Synaptol 50 Tablet is a centrally-acting muscle relaxant. It works on the brain and spinal cord to relieve muscle stiffness and contraction without reducing muscle strength. Additionally, it improves blood flow to the muscles and can block pain signals, thereby enhancing muscle movement and reducing pain.

What is the usual dosage for Synaptol 50 Tablet?

For adults, the typical dosage is 50-150 mg of Tolperisone hydrochloride, taken three times daily. For children over 6 years of age, the dosage is generally 5 mg/kg/day in three divided doses, and for children aged 6-14 years, it is 2-4 mg/kg/day in three divided doses. Synaptol 50 Tablet should always be taken with food.

What are the possible side effects of Synaptol 50 Tablet?

Common side effects can include drowsiness, dizziness, nausea, vomiting, stomach upset, diarrhea, dry mouth, abdominal pain, sweating, rash or redness on the skin, weakness, constipation, flatulence, headache, and arterial hypotension. If any side effects persist or worsen, it is important to inform your doctor.

Is Synaptol 50 Tablet safe during pregnancy or breastfeeding?

Synaptol 50 Tablet should be used with caution during pregnancy, and it is advised to consult a doctor. It is generally considered unsafe and should not be used by breastfeeding mothers.

Can Synaptol 50 Tablet be taken with other medications?

You should inform your doctor about all medications you are currently taking, as some may interact with Synaptol 50 Tablet. For example, concomitant use with Methocarbamol has been reported to cause visual accommodation disturbance. Avoid consuming large amounts of grapefruit or grapefruit juice, as this may increase the risk of side effects.

What precautions should be taken while using Synaptol 50 Tablet?

Synaptol 50 Tablet should be used with caution in children below 14 years of age and elderly patients. Caution is also advised for individuals with pre-existing liver or kidney diseases. It is contraindicated in patients with myasthenia gravis or known hypersensitivity to Tolperisone. Due to potential dizziness or drowsiness, avoid driving or operating machinery until you know how the medicine affects you. Alcohol consumption should be avoided as it may increase sedative effects. Do not stop taking this medication abruptly without consulting your doctor, as it may lead to withdrawal symptoms or a worsening of the condition.

What happens if a dose of Synaptol 50 Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule.

How should Synaptol 50 Tablet be stored?

Synaptol 50 Tablet should be stored in a cool and dry place, below 30°C, and protected from light and moisture. It is important to keep it out of sight and reach of children.