Cildip 5mg

CILDIP 5MG

CILDIP 5MG is a medication primarily used for the management of hypertension, commonly known as high blood pressure. It is manufactured by Medley Pharmaceuticals.

• Composition

  • Active Ingredient: Cilnidipine (5mg)

• Uses CILDIP 5MG is prescribed for various cardiovascular conditions:

  • Treatment of hypertension (high blood pressure).
  • Prevention of heart attack and stroke.
  • Prevention and management of angina (heart-related chest pain).
  • It is also indicated for end-organ protection and is reported to be beneficial in elderly patients, as well as those with diabetes and albuminuria, and chronic kidney disease.

• Dosage and Administration

  • Adults: The typical dosage is 5-10 mg once daily, preferably taken after breakfast.
  • The maximum recommended dose is 20 mg once daily.
  • CILDIP 5MG tablets should be swallowed whole with a glass of water and not crushed, chewed, or broken.
  • It is important to take the medicine at the same time each day to maintain consistent blood pressure control.
  • Do not discontinue the medication suddenly without consulting a doctor, as it may worsen the condition.

• Side Effects Common side effects may include:

  • Headache, dizziness, sleepiness, and fatigue.
  • Flushing (sense of warmth in the face, ears, neck, and trunk).
  • Palpitations (unusual beating of the heart).
  • Edema, particularly swelling in the feet or ankles.
  • Nausea, stomach pain, or other gastrointestinal disturbances.
  • Rash, itching.
  • Increased urination frequency.
  • Gingival hyperplasia (enlargement or overgrowth of the gums).
  • Less common but serious side effects can include severe hypotension (low blood pressure) and irregular heartbeat.

• Precautions

  • Allergies: Contraindicated in patients with known hypersensitivity to cilnidipine or any of its excipients.
  • Pregnancy and Breastfeeding: Consult a doctor if pregnant, planning to be pregnant, or breastfeeding, as information on use during these periods is limited or not recommended.
  • Driving and Operating Machinery: CILDIP 5MG may cause dizziness, affecting the ability to drive or operate machinery. Exercise caution until you know how the medicine affects you.
  • Alcohol: Caution is advised when consuming alcohol with CILDIP 5MG, as it may enhance certain side effects.
  • Medical Conditions: Administer with caution in patients with serious hepatic (liver) dysfunction, kidney disease, severe hypotension, congestive heart failure, or a history of serious adverse reactions to calcium antagonists. It is contraindicated in cardiogenic shock, recent myocardial infarction (MI), acute unstable angina, and severe aortic stenosis.
  • Drug Interactions: Inform your doctor about all other medications, herbal preparations, and supplements you are taking, especially other anti-hypertensives, antipsychotics, antiepileptics (e.g., carbamazepine, phenytoin), antibiotics (e.g., erythromycin), anti-TB agents (e.g., rifampicin), and cardiac agents (e.g., quinidine, digoxin).
  • Discontinuation: The dosage should be gradually decreased under close observation when discontinuing the medicine.

• Storage

  • Store in a cool and dry place, protected from direct sunlight, moisture, and heat.
  • Keep out of sight and reach of children and pets.
  • Do not use expired or damaged medicines. Typically, store below 25°C or 30°C.

CILDIP 5MG by MEDLEY VOZOCARE contains the active ingredient Cilnidipine 5mg, which is a calcium channel blocker used to treat high blood pressure.

What is CILDIP 5MG used for?

CILDIP 5MG is primarily used to treat high blood pressure (hypertension). It also helps in the prevention of heart attacks and strokes, and can be prescribed for conditions like angina (chest pain related to heart issues) and arrhythmia (irregular heartbeat). Additionally, it may be beneficial for elderly patients and those with diabetes and kidney disease, including those with albuminuria.

How does CILDIP 5MG work?

CILDIP 5MG, containing Cilnidipine, works as a dual L-type and N-type calcium channel blocker. It relaxes and widens blood vessels by inhibiting calcium influx into vascular smooth muscles, which decreases peripheral vascular resistance and lowers blood pressure. Uniquely, it also blocks N-type calcium channels in sympathetic nerve endings, reducing the release of norepinephrine and helping to prevent an increase in heart rate during blood pressure reduction, as well as suppressing stress-related hypertension.

What is the usual dosage of CILDIP 5MG?

For adults, the usual starting dose is 5-10 mg once daily, preferably after breakfast. The dosage can be increased up to a maximum of 20 mg once daily if a sufficient response is not achieved. It is recommended to take the medicine at the same time each day to maintain consistent levels in the body. For elderly patients, treatment should be initiated with the lowest possible dose (5 mg) due to increased susceptibility to low blood pressure.

What are the possible side effects of CILDIP 5MG?

Common side effects may include headache, dizziness, flushing (redness of the face), fatigue, lethargy, peripheral edema (swelling in the feet or ankles), nausea, abdominal pain, palpitations, and increased frequency of urination. Most of these side effects are usually temporary and resolve over time. If any side effects persist or worsen, it is important to consult your doctor.

Is CILDIP 5MG safe during pregnancy or breastfeeding?

CILDIP 5MG is generally not recommended during pregnancy or for women who may be pregnant. Animal studies have indicated potential fetal toxicity and prolonged gestation and delivery times. For breastfeeding mothers, CILDIP 5MG is also not recommended. If its administration is considered indispensable, breastfeeding should be discontinued, as the drug has been found in the milk of lactating rats.

Can CILDIP 5MG be taken with other medications?

CILDIP 5MG can interact with several medications. Its therapeutic effects may be enhanced when taken with cimetidine or certain azole antifungal agents (e.g., miconazole, itraconazole). Caution is advised when taking it with other antihypertensive agents, antiarrhythmic agents (like quinidine or amlodipine), antiepileptic medications (e.g., phenytoin, carbamazepine), antituberculosis drugs (like rifampicin), certain antibiotics (e.g., erythromycin), and antipsychotic medications, as these can lead to additive effects or low blood pressure. Nonsteroidal anti-inflammatory drugs (NSAIDs) may reduce its blood pressure-lowering effect.

What precautions should be taken while taking CILDIP 5MG?

Avoid abruptly stopping CILDIP 5MG, as this can worsen symptoms or cause a sudden increase in blood pressure; the dosage should be gradually decreased under close medical observation. Use with caution if you have severe aortic stenosis, hypertrophic cardiomyopathy, heart failure, very low blood pressure (hypotension), or severe liver or kidney problems. CILDIP 5MG may cause dizziness or fainting, especially when starting treatment, so avoid driving or operating heavy machinery if you experience these effects. Consumption of grapefruit or grapefruit juice is contraindicated, as it can increase the drug's concentration and lead to serious side effects. Alcohol should also be avoided as it can enhance the blood pressure-lowering effect.

What happens if a dose of CILDIP 5MG is missed?

If you miss a dose of CILDIP 5MG, take it as soon as you remember, unless it is almost time for your next scheduled dose. If it is close to the time for the next dose, skip the missed dose and continue with your regular dosing schedule. It is crucial not to take a double dose to make up for a missed one, as this can cause your blood pressure to drop too low and may lead to side effects like severe dizziness or fainting.

How should CILDIP 5MG be stored?

CILDIP 5MG tablets should be stored below 30°C (some sources specify below 25°C), in a cool and dry place, protected from direct sunlight and moisture. Always keep this medicine out of the sight and reach of children.