Tamdura Capsule (10 Cap)

TAMDURA CAPSULE (10 CAP) by SUN PHARMACEUTICAL IND.LTD.

Tamdura Capsule is a combination medication primarily used for the management of Benign Prostatic Hyperplasia (BPH), also known as an enlarged prostate gland, in men. It helps to alleviate bothersome urinary symptoms associated with BPH, improving comfort and quality of life.

• Name:

  • Common Name: Tamdura Capsule, Tamdura Capsule PR
  • Brand Name: TAMDURA CAPSULE (10 CAP) by SUN PHARMACEUTICAL IND.LTD.

• Composition:

  • Active Ingredients: Each capsule contains Tamsulosin (0.4 mg) and Dutasteride (0.5 mg).
  • Tamsulosin is an alpha-blocker that relaxes the muscles around the bladder exit and prostate gland, facilitating easier urine passage. Dutasteride is a 5-alpha-reductase inhibitor that works by reducing the production of dihydrotestosterone (DHT), a hormone responsible for prostate growth, thereby shrinking the prostate gland.

• Uses:

  • Treatment of Benign Prostatic Hyperplasia (BPH) symptoms, including:
    • Difficulty initiating urination.
    • Frequent or urgent need to urinate, especially at night.
    • Weak urine flow.
    • Inability to empty the bladder completely.
  • Minimizes the risk of acute urinary retention and the need for prostate surgery.

• Dosage and Administration:

  • Typically, one capsule is taken orally per day.
  • It should be taken approximately 30 minutes after the same meal each day (e.g., after breakfast or the first daily meal) to ensure consistent drug levels.
  • The capsule should be swallowed whole with water and not chewed, crushed, or broken.
  • Do not miss doses, even if feeling well, as it may take up to 4 weeks to notice an improvement and up to 6 months for the full benefit.

• Side Effects:

  • Common Side Effects: Impotence (difficulty achieving or maintaining an erection), decreased libido (sex drive), ejaculation disorder (including decreased semen volume), dizziness, breast enlargement (gynecomastia), and breast tenderness.
  • Serious Side Effects (rare): Allergic reactions (skin rash, itching, hives, swelling of face/limbs) and Stevens-Johnson syndrome (severe rash with blisters and peeling skin).

• Precautions:

  • Contraindications: Not for use in women or children under 18 years of age. Pregnant women should not even handle the capsules due to skin absorption and potential harm to a fetus.
  • Medical Conditions: Inform your doctor if you have low blood pressure, liver disease, kidney disease, or a history of heart problems.
  • Drug Interactions: Avoid concomitant use with other alpha-blockers, medicines for erectile dysfunction (e.g., sildenafil, tadalafil), certain antifungals (e.g., ketoconazole), some blood pressure medications (e.g., verapamil, diltiazem), HIV medications (e.g., ritonavir), and some antidepressants (e.g., paroxetine).
  • Alcohol: Avoid alcohol consumption as it can increase dizziness and drowsiness.
  • Surgery: Inform your eye doctor about Tamdura use before cataract or glaucoma surgery, as it may cause Intraoperative Floppy Iris Syndrome (IFIS).
  • Sexual Activity: Fertile men should use a condom during sexual intercourse as the medicine is found in semen. Tamdura can affect semen volume, sperm count, and movement. Do not donate blood for 6 months after the last dose.
  • Driving/Operating Machinery: May cause dizziness or drowsiness; avoid activities requiring concentration until you know how the medicine affects you.

• Storage:

  • Store in a cool, dry place below 30°C (86°F), away from direct sunlight and moisture.
  • Keep out of sight and reach of children and pets.

Frequently Asked Questions about Tamdura Capsule

What is Tamdura Capsule used for?

Tamdura Capsule is primarily used to treat Benign Prostatic Hyperplasia (BPH), also known as an enlarged prostate gland, in men. This condition can lead to urinary issues such as difficulty passing urine, frequent urination, weak urine flow, and a feeling of incomplete bladder emptying. It helps to relieve these symptoms and can reduce the risk of sudden urine blockage and the need for prostate surgery.

How does Tamdura Capsule work?

Tamdura Capsule contains two active ingredients: Tamsulosin and Dutasteride. Tamsulosin is an alpha-blocker that works by relaxing the muscles in the prostate gland and the bladder neck, which makes it easier for urine to pass. Dutasteride is a 5-alpha reductase inhibitor that reduces the production of dihydrotestosterone (DHT), a hormone responsible for prostate enlargement. By inhibiting DHT, dutasteride helps to shrink the size of the enlarged prostate gland over time. Together, these two components work to improve urinary flow and relieve BPH symptoms.

What is the usual dosage for Tamdura Capsule?

The usual dosage for Tamdura Capsule is one capsule per day, taken orally. It should be taken about 30 minutes after the same meal each day, or as advised by your doctor. The capsule should be swallowed whole with water and not chewed, crushed, or broken. Your doctor will determine the appropriate dose and duration of treatment based on your medical condition and response to the medication.

What are the possible side effects of Tamdura Capsule?

Common side effects of Tamdura Capsule can include dizziness, lightheadedness, drowsiness, decreased sex drive (libido), ejaculation problems (such as reduced semen volume), impotence, increased breast size, or breast tenderness. Most of these side effects are usually temporary and may resolve over time. If they persist or worsen, consult your doctor. Serious allergic reactions are rare but require immediate medical attention.

Is Tamdura Capsule safe during pregnancy or breastfeeding?

Tamdura Capsule is intended for use only in men and is not recommended for women. Pregnant women should not come into contact with Tamdura Capsule, as it can be absorbed through the skin and may cause potential abnormalities in a male fetus. If a fertile man is taking Tamdura Capsule and his partner is pregnant or may become pregnant, using a condom during sexual intercourse is recommended as the medicine is found in semen.

Can Tamdura Capsule be taken with other medications?

Tamdura Capsule can interact with certain other medications. It's important to inform your doctor about all medicines, supplements, or herbal products you are currently taking to avoid potential interactions. Some medications that may interact with Tamdura Capsule include:

• Other alpha-blockers (e.g., prazosin, doxazosin, terazosin).
• Medicines for erectile dysfunction (e.g., vardenafil, sildenafil, tadalafil).
• Antifungals (e.g., ketoconazole, itraconazole).
• Certain blood pressure-lowering medicines (e.g., verapamil, diltiazem).
• Medicines for HIV infection (e.g., ritonavir, indinavir).
• Medicines for depression (e.g., paroxetine, nefazodone).
• Blood thinners (e.g., warfarin) and certain antibiotics (e.g., erythromycin), and NSAIDs (e.g., diclofenac).

What precautions should be taken with Tamdura Capsule?

• Low Blood Pressure: Inform your doctor if you have low blood pressure, as Tamdura Capsule can cause dizziness or lightheadedness, especially when standing up quickly.
• Liver/Kidney Disease: Use with caution if you have liver or kidney disease.
• Surgery: If you are scheduled for eye surgery (especially cataract or glaucoma surgery), inform your eye doctor about your use of Tamdura Capsule, as it may affect the procedure.
• Alcohol: Avoid alcohol consumption while taking this medicine, as it may increase side effects like dizziness and drowsiness.
• Driving/Operating Machinery: Do not drive or operate machinery if you experience dizziness or blurred vision.
• Children: Tamdura Capsule is not recommended for individuals under 18 years of age.
• Allergies: Do not take if you are allergic to Tamsulosin, Dutasteride, or any other ingredients, including soya or peanuts.

What happens if a dose is missed?

If you miss a dose of Tamdura Capsule, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one, as this can increase the risk of side effects.

How should Tamdura Capsule be stored?

Tamdura Capsule should be stored in a cool, dry place, away from direct sunlight and moisture. Keep it out of sight and reach of children and pets. The typical storage temperature is below 30°C (86°F).