Glura M 500 Mg Tablet (15 Tab)

GLURA M 500 MG TABLET

GLURA M 500 MG Tablet is a combination medication used to manage high blood sugar levels in adults with type 2 diabetes mellitus. It is manufactured by Eris Lifesciences Limited.

• Composition:

  • Active Ingredients: Each tablet contains Sitagliptin (50 mg) and Metformin (500 mg).

• Uses: GLURA M 500 MG Tablet is prescribed for the treatment of type 2 diabetes mellitus. It works to control high blood sugar levels, helping to prevent serious complications associated with diabetes such as kidney damage, eye damage, nerve problems, and may reduce the risk of heart attack or stroke.

• Dosage and Administration: This medicine should be taken orally, preferably with meals, to minimize gastrointestinal discomfort. It is usually taken once or twice daily, as prescribed by your doctor. Swallow the tablet whole with a glass of water; do not crush, chew, or break it. For optimal benefits, take it regularly at the same time each day to maintain consistent blood sugar levels. Do not stop taking this medicine without consulting your doctor.

• Side Effects:

  • Common Side Effects: Diarrhea, headache, upper respiratory tract infection (nasopharyngitis), nausea, vomiting, abdominal pain, loss of appetite, metallic taste, and hypoglycemia (low blood sugar).
  • Serious Side Effects: Lactic acidosis (a rare but serious condition), allergic reactions (rash, itching, swelling), liver problems (jaundice, dark urine), decreased vitamin B12 absorption, pancreatitis, and severe skin reactions like bullous pemphigoid. Seek immediate medical attention if you experience severe symptoms.

• Precautions: Inform your doctor if you have any allergies to the components of this medicine. Avoid use if you have severe kidney impairment, liver impairment, congestive heart failure, lactic acidosis, or diabetic ketoacidosis. Consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Alcohol consumption is unsafe with GLURA M 500 MG Tablet as it can increase the risk of lactic acidosis and hypoglycemia. Exercise caution if you have heart disease, a history of kidney problems, or are prone to vitamin B12 deficiency. Inform your doctor about all other medicines you are taking, as interactions can occur with carbonic anhydrase inhibitors, beta-blockers, corticosteroids, and diuretics.

• Storage: Store GLURA M 500 MG Tablet at room temperature, ideally below 30°C. Keep it in its original package, away from moisture and damp places like the bathroom. Ensure the medicine is stored out of reach of children and pets. Always use the medicine before its expiry date.

What is GLURA M 500 MG TABLET used for?

GLURA M 500 MG TABLET is primarily used to manage high blood sugar levels in adults with type 2 diabetes mellitus. It is typically prescribed alongside a healthy diet and regular exercise to help control both fasting and post-meal blood sugar levels, aiming to prevent serious complications of diabetes such as kidney damage, eye damage, nerve problems, heart attack, or stroke.

How does GLURA M 500 MG TABLET work?

GLURA M 500 MG TABLET contains two active ingredients: Metformin (500 mg) and Sitagliptin (50 mg). Metformin works by reducing the amount of glucose produced by the liver, decreasing glucose absorption from the intestines, and enhancing the body's sensitivity to insulin. Sitagliptin is a DPP-4 inhibitor that helps regulate insulin levels by increasing insulin release from the pancreas after eating and decreasing the amount of sugar made by the liver. Together, these actions help to keep blood sugar levels in check.

What is the usual dosage for GLURA M 500 MG TABLET?

The usual starting dose is generally one tablet (500mg) once or twice daily, taken with meals to minimize gastrointestinal discomfort. Your doctor may gradually increase the dosage based on your blood glucose levels, potentially up to a maximum of 2000mg per day. It is crucial to adhere to the prescribed dosage and timing and not to adjust it without your doctor's advice.

What are the possible side effects of GLURA M 500 MG TABLET?

Common side effects may include upper respiratory tract infection, nasopharyngitis (common cold symptoms), headache, nausea, diarrhea, and abdominal pain. Hypoglycemia (low blood sugar) is also a possible side effect, especially if taken with other diabetes medications. Less common but serious side effects can include lactic acidosis and, with long-term use, a deficiency in Vitamin B12.

Is GLURA M 500 MG TABLET safe during pregnancy or breastfeeding?

Caution is advised when taking GLURA M 500 MG TABLET during pregnancy, and it is best to consult your doctor. It is generally not recommended for breastfeeding women unless deemed necessary by a doctor, who will discuss potential risks and benefits.

Can GLURA M 500 MG TABLET be taken with other medications?

GLURA M 500 MG TABLET can interact with certain medications, including carbonic anhydrase inhibitors (like topiramate), beta-blockers (like atenolol), corticosteroids (like prednisone), and diuretics (like furosemide). It can also interact with other antidiabetic medicines. It is essential to inform your doctor about all other medicines, supplements, or herbal products you are currently taking to avoid potential interactions.

What precautions should be taken while using GLURA M 500 MG TABLET?

Avoid consuming alcohol while on this medication as it can increase the risk of lactic acidosis. Inform your doctor if you have kidney, liver, or heart disease, problems with your pancreas, or a history of vitamin B12 deficiency. GLURA M 500 MG TABLET is not recommended for patients with severe kidney or liver impairment, type 1 diabetes mellitus, or diabetic ketoacidosis. Taking the tablet with meals can help reduce the risk of stomach upset. Regular monitoring of blood sugar levels and kidney function is crucial during treatment.

What happens if a dose of GLURA M 500 MG TABLET is missed?

If you miss a dose of GLURA M 500 MG TABLET, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should GLURA M 500 MG TABLET be stored?

Store GLURA M 500 MG TABLET at room temperature, ideally below 30°C. Keep it in its original package to protect it from moisture and ensure it is stored out of the reach of children. Make sure to use the medicine before its expiry date.