Huminsulin 50/50 Injection 40 Iu 10ml (vial)

HUMINSULIN 50/50 INJECTION 40 IU 10ML (VIAL) by LUPIN LTD.

HUMINSULIN 50/50 is a pre-mixed insulin formulation used to manage blood sugar levels in individuals with diabetes mellitus.

• Name:

  • Common Name: Human Insulin (Biphasic Isophane Insulin)
  • Brand Name: HUMINSULIN 50/50

• Composition:

  • HUMINSULIN 50/50 contains a combination of 50% Insulin Isophane (intermediate-acting) and 50% Human Insulin (soluble, rapid-acting) in a 40 IU/ml concentration.

• Uses:

  • This medicine is prescribed for the treatment of both Type 1 and Type 2 Diabetes Mellitus in adults and children. It works by improving glucose uptake by muscle and fat cells and suppressing sugar production in the liver, providing both immediate and sustained blood sugar control.

• Dosage and Administration:

  • HUMINSULIN 50/50 is typically administered subcutaneously (under the skin) 30 minutes before a meal, usually twice daily. The injection sites should be rotated (e.g., abdomen, upper arm, thigh, buttocks) to prevent skin problems like lipodystrophy. It is crucial to use a U-100 insulin syringe. Do not administer intravenously.

• Side Effects:

  • Common side effects include hypoglycemia (low blood sugar), which can manifest as sweating, dizziness, shaking, headache, and hunger. Other common reactions at the injection site may include pain, redness, swelling, itching, or skin thickening (lipodystrophy). Weight gain can also occur. Serious side effects are rare but can include severe allergic reactions.

• Precautions:

  • Alcohol consumption is unsafe as it can cause severe low blood sugar. Patients with kidney, liver, or heart problems should use this medicine with caution. Insulin requirements can change with illness, pregnancy, certain medications (e.g., corticosteroids, oral contraceptives), and exercise. Never share needles or syringes. Always carry a fast-acting source of sugar for hypoglycemia.

• Storage:

  • Unopened vials should be stored in a refrigerator between 2°C to 8°C. Do not freeze. Once opened, the vial can be stored at room temperature (below 30°C) for up to 28 days, protected from direct heat and light. Discard any opened vial after 28 days.

HUMINSULIN 50/50 INJECTION 40 IU 10ML (VIAL) by LUPIN LTD. - Frequently Asked Questions

What is HUMINSULIN 50/50 INJECTION used for?

HUMINSULIN 50/50 INJECTION is a combination of intermediate-acting and short-acting human insulin used to control high blood sugar in individuals with diabetes mellitus (both type 1 and type 2). It helps manage blood sugar levels in both adults and children. It aims to improve overall blood sugar control.

How does HUMINSULIN 50/50 INJECTION work?

This medicine contains 50% human insulin isophane (intermediate-acting) and 50% human insulin (short-acting or rapid-acting). The rapid-acting component quickly lowers blood sugar levels after meals, while the intermediate-acting component provides sustained blood sugar control between meals and overnight. It works by stimulating the uptake of glucose by muscle and fat cells and by suppressing the production of sugar by the liver.

What is the usual dosage for HUMINSULIN 50/50 INJECTION?

The dosage of HUMINSULIN 50/50 INJECTION is highly individualized and must be determined by a healthcare professional based on factors such as blood glucose levels, diet, activity level, and other medications. It is typically injected subcutaneously (under the skin) 15 to 30 minutes before a meal. It is usually administered twice daily, before breakfast and before dinner. Always follow your doctor's instructions carefully.

What are the possible side effects of HUMINSULIN 50/50 INJECTION?

The most common side effect is low blood sugar (hypoglycemia), which can manifest as sweating, dizziness, shaking, fast heartbeat, hunger, confusion, or weakness. Other common side effects may include injection site reactions (pain, redness, swelling, irritation), weight gain, rash, itching, or edema (swelling). Serious side effects, though rare, can include severe allergic reactions, hypokalemia (low potassium levels), or worsening of heart failure when used with certain other diabetes medications. Seek immediate medical attention if you experience severe symptoms.

Is HUMINSULIN 50/50 INJECTION safe during pregnancy or breastfeeding?

HUMINSULIN 50/50 INJECTION is generally considered safe to use during pregnancy if prescribed by a doctor. However, maintaining good blood sugar control is crucial during pregnancy, and insulin requirements may change, so consult your doctor. It is also considered probably safe during breastfeeding, but your insulin needs may change, and a doctor's consultation is recommended.

Can HUMINSULIN 50/50 INJECTION be taken with other medications?

HUMINSULIN 50/50 can interact with various medications. Tell your doctor about all medications and supplements you use, including non-prescription drugs, as some can increase or decrease your insulin requirements or affect blood sugar levels. For example, certain diabetes drugs like thiazolidinediones (e.g., pioglitazone, rosiglitazone) when used with insulin may increase the risk of heart failure. Alcohol consumption is generally unsafe as it can cause severe low blood sugar.

What precautions should be taken with HUMINSULIN 50/50 INJECTION?

Do not use this medicine if you have low blood glucose levels (hypoglycemia). Inform your doctor if you have kidney, liver, or heart problems, as dose adjustments or caution may be needed. Regular blood sugar monitoring is essential. Avoid driving or operating machinery if your blood sugar is too low or too high. Never share needles or syringes.

What happens if a dose of HUMINSULIN 50/50 INJECTION is missed?

If you miss a dose, take it as soon as you remember, especially if it's within a reasonable timeframe (e.g., 1-2 hours) of the usual injection time. If it's already close to the next scheduled dose, do not take a double dose to make up for the missed one; instead, skip the missed dose and continue with your regular schedule. Always check your blood sugar levels more frequently and consult your doctor for specific guidance, especially for mixed insulins like Huminsulin 50/50.

How should HUMINSULIN 50/50 INJECTION be stored?

Unopened vials of HUMINSULIN 50/50 should be stored in a refrigerator at a temperature between 2°C and 8°C (36°F and 46°F). Do not freeze the medicine. Once opened, the vial can be kept unrefrigerated at room temperature (below 30°C or 86°F) for up to 28 days, away from direct heat and light. Discard any opened vial after 28 days, even if it still contains insulin. Keep out of reach of children.