Amlokind Beta 25 Mg Tablet (10 Tab)

AMLOKIND BETA 25 MG TABLET

Amlokind Beta 25 mg Tablet, manufactured by Mankind Pharma Ltd., is a combination medication used for the comprehensive management of cardiovascular conditions.

Composition Each tablet contains Amlodipine 5 mg and Metoprolol Succinate 25 mg. Amlodipine is a calcium channel blocker that relaxes and widens blood vessels, while Metoprolol is a beta-blocker that slows the heart rate and relaxes blood vessels, collectively reducing the heart's workload.

Uses This medicine is primarily prescribed for:

• Hypertension (high blood pressure)
• Angina pectoris (heart-related chest pain)
• Abnormal heart rhythms
• Chronic (long-term) heart failure
• Coronary artery disease

Dosage and Administration Amlokind Beta 25 mg Tablet should be taken orally as directed by a physician, preferably at the same time each day for consistent results. It can be taken with or without food. The tablet should be swallowed whole with water and not crushed, chewed, or broken. Do not stop taking this medicine suddenly without medical advice, as it can lead to serious complications.

Side Effects Common side effects may include:

• Headache, dizziness, fatigue, sleepiness
• Nausea, vomiting, diarrhea, constipation
• Slow heart rate (bradycardia), palpitations
• Ankle swelling (edema), flushing, muscle cramps
• Skin rash, depression

Serious side effects, though rare, can include allergic reactions, severe skin reactions, abnormal heart rhythm, or heart attack. Seek immediate medical attention if these occur.

Precautions

• Contraindications: Avoid use if allergic to any ingredients, or if you have severe asthma, lung disease, certain heart rhythm problems, uncontrolled heart failure, or have recently had a heart attack.
• Alcohol: Unsafe to consume alcohol with this medicine.
• Pregnancy and Breastfeeding: Consult your doctor before use.
• Liver/Kidney Conditions: Use with caution and inform your doctor, as dose adjustments may be necessary.
• Diabetes: Metoprolol may mask signs of low blood sugar.
• Food Interactions: Avoid grapefruit and grapefruit juice.
• Driving: May cause dizziness or sleepiness; use caution when driving or operating machinery.

Storage Store in a cool and dry place, protected from sunlight, at temperatures between 10ºC to 25ºC or below 30ºC. Keep out of sight and reach of children.

What is AMLOKIND BETA 25 MG TABLET used for?

AMLOKIND BETA 25 MG TABLET is primarily used to treat high blood pressure (hypertension) and heart-related chest pain (angina). It can also be used to manage irregular heart rhythms and chronic (long-term) heart failure, helping to improve blood flow and reduce strain on the heart, thereby lowering the risk of heart attack and stroke.

How does AMLOKIND BETA 25 MG TABLET work?

This medicine contains two active ingredients: Amlodipine and Metoprolol. Amlodipine is a calcium channel blocker that relaxes and widens blood vessels by blocking calcium entry into heart and vessel walls, improving oxygen delivery to the heart. Metoprolol is a beta-blocker that slows down the heart rate and relaxes blood vessels by blocking the effects of certain stress hormones, which helps lower blood pressure. Both work together to make the heart more efficient at pumping blood.

What is the usual dosage for AMLOKIND BETA 25 MG TABLET?

AMLOKIND BETA 25 MG TABLET should be taken as directed by your physician. It can be taken with or without food, but it is best to take it at the same time each day for consistent blood levels and better results. You should swallow the whole tablet with a glass of water and not crush, chew, or break it. Your doctor will determine the appropriate dose and duration based on your condition.

What are the possible side effects of AMLOKIND BETA 25 MG TABLET?

Common side effects may include headache, dizziness, fatigue, nausea, slow heart rate, ankle swelling, breathlessness, and depression. Most of these side effects do not require medical attention and resolve over time. However, if any side effects are persistent or severe, such as allergic reactions (itching, swelling, difficulty breathing), severe skin reactions, abnormal heartbeat, or chest pain, you should contact your doctor immediately.

Is AMLOKIND BETA 25 MG TABLET safe during pregnancy or breastfeeding?

If you are pregnant, caution is advised while taking AMLOKIND BETA 25 MG TABLET. Amlodipine's safety during pregnancy is not well-established, and animal studies have shown potential harmful effects on a developing baby. Metoprolol has also been associated with reports of intrauterine growth restriction and preterm birth. For breastfeeding, both amlodipine and metoprolol pass into breast milk. While the risk to the infant is generally considered low, monitoring the infant for any adverse effects like slow heart rate or low blood pressure is recommended. Always consult your doctor to weigh the potential risks and benefits before using this medicine during pregnancy or breastfeeding.

Can AMLOKIND BETA 25 MG TABLET be taken with other medications?

AMLOKIND BETA 25 MG TABLET can interact with other medications. It is crucial to inform your doctor about all medicines, supplements, or herbal remedies you are taking. Interactions can occur with other blood pressure-lowering medications, antifungal medicines (e.g., ketoconazole, itraconazole), certain antibiotics (e.g., rifampicin), medicines for irregular heartbeats (e.g., quinidine, amiodarone), certain antidepressants (e.g., SSRIs, tricyclics, MAOIs), and phenytoin. Additionally, avoid grapefruit or grapefruit juice, as it can increase the concentration of Amlokind Beta and worsen its side effects.

What precautions should be taken while taking AMLOKIND BETA 25 MG TABLET?

Before taking this medicine, inform your doctor if you have any pre-existing conditions such as liver or kidney problems, heart conditions (e.g., heart failure, heart block, slow heart rate), diabetes, asthma, or severe breathing difficulties. Metoprolol, an ingredient in this medicine, can mask the warning signs of low blood sugar in diabetics. Avoid consuming alcohol as it can further lower blood pressure. Regular monitoring of blood pressure, kidney function, and electrolyte levels may be necessary. Do not stop taking this medicine suddenly without consulting your doctor, as abrupt discontinuation can lead to severe chest pain, abnormal heart rhythms, or even a heart attack.

What happens if a dose of AMLOKIND BETA 25 MG TABLET is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should AMLOKIND BETA 25 MG TABLET be stored?

Store AMLOKIND BETA 25 MG TABLET in a cool and dry place, protected from sunlight and moisture. The recommended storage temperature is below 30°C (or between 10ºC to 25ºC). Keep this medicine out of sight and reach of children.