Sitaglo M 100mg/500mg Tab

SITAGLO M 100MG/500MG Tablet (ARISTO PHARMA)

SITAGLO M 100MG/500MG Tablet is a combination medication primarily used for the management of Type 2 Diabetes Mellitus in adults. Manufactured by Aristo Pharmaceuticals Pvt Ltd, this medicine helps to effectively control high blood sugar levels.

• Name:

  • Brand Name: SITAGLO M 100MG/500MG Tablet (often appears as SITAGLO M SR 100MG/500MG Tablet, indicating sustained-release)
  • Common Name: Sitagliptin and Metformin Hydrochloride Tablets

• Composition:

  • Each tablet contains:
    • Sitagliptin: 100 mg
    • Metformin Hydrochloride: 500 mg

• Uses: SITAGLO M is prescribed to help regulate blood sugar levels in adults with Type 2 Diabetes Mellitus, especially when diet and exercise alone are insufficient. It works by increasing insulin secretion, decreasing glucose production in the liver, and improving the body's response to insulin, thereby maintaining stable blood sugar and reducing the risk of associated complications like kidney damage, eye damage, nerve problems, and cardiovascular issues.

• Dosage and Administration: Typically, the starting dose is one tablet, once or twice daily, taken with meals to minimize gastrointestinal discomfort. The tablet should be swallowed whole with a full glass of water and not crushed, chewed, or broken. Dosage adjustments are made by a healthcare professional based on blood glucose levels and individual response.

• Side Effects:

  • Common Side Effects: Nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste, headache, and hypoglycemia (low blood sugar), especially when used with other diabetes medications.
  • Serious Side Effects (Rare): Lactic acidosis (symptoms include unusual muscle pain, trouble breathing, stomach pain, feeling cold, dizziness), pancreatitis, severe allergic reactions, and liver problems.

• Precautions: SITAGLO M is not suitable for individuals with Type 1 diabetes or diabetic ketoacidosis. Patients with severe kidney or liver disease should avoid this medication. Inform your doctor about existing medical conditions, allergies, or other medications. Avoid excessive alcohol consumption due to an increased risk of lactic acidosis. Caution is advised during pregnancy and breastfeeding, and a doctor should be consulted. Regular monitoring of blood sugar levels and kidney function is crucial.

• Storage: Store the medicine at room temperature (below 30°C). Keep it in its original container or pack, away from sunlight and moisture. Ensure it is out of sight and reach of children.

SITAGLO M 100MG/500MG TAB is a medication commonly prescribed for the management of Type 2 Diabetes Mellitus. It combines two active ingredients, sitagliptin and metformin, to help control blood sugar levels when diet and exercise alone are not sufficient. This medication works by addressing different aspects of glucose regulation in the body.

Here are some frequently asked questions about SITAGLO M 100MG/500MG TAB:

What is SITAGLO M 100MG/500MG TAB used for?

SITAGLO M 100MG/500MG TAB is used, along with proper diet and exercise, to treat high blood sugar levels in adults with Type 2 Diabetes Mellitus. It helps improve glycemic control and reduces the risk of diabetes-related complications such as kidney damage, nerve disorders, heart disease, and vision problems.

How does SITAGLO M 100MG/500MG TAB work?

This medicine contains two active ingredients:

• Sitagliptin: A dipeptidyl peptidase-4 (DPP-4) inhibitor, sitagliptin increases the levels of natural substances called incretins in the body. Incretins help the pancreas release more insulin, especially after meals, and signal the liver to reduce its sugar production when blood sugar is high.
• Metformin: A biguanide, metformin works by decreasing glucose production in the liver, reducing the absorption of sugar from the intestines, and improving the body's sensitivity to insulin, allowing it to use sugar more effectively. Together, these mechanisms provide comprehensive control over blood sugar levels.

What is the usual dosage for SITAGLO M 100MG/500MG TAB?

The dosage of SITAGLO M is individualized by your doctor based on your current antidiabetic regimen, effectiveness, and tolerability. It is typically taken once or twice daily with meals to minimize gastrointestinal discomfort. The maximum recommended daily dose is usually not more than 100 mg of sitagliptin and 2000 mg of metformin. It is crucial to follow your doctor's instructions exactly.

What are the possible side effects of SITAGLO M 100MG/500MG TAB?

Common side effects may include nausea, vomiting, diarrhea, stomach upset, headache, and a metallic taste in the mouth. More serious but rare side effects can include severe joint pain, pancreatitis (sudden and severe stomach pain), bullous pemphigoid (large, hard skin blisters), and lactic acidosis (a serious condition associated with metformin, characterized by symptoms like unusual muscle pain, difficulty breathing, and extreme tiredness). Long-term use of metformin can also lead to Vitamin B12 deficiency.

Is SITAGLO M 100MG/500MG TAB safe during pregnancy or breastfeeding?

SITAGLO M is generally not recommended during pregnancy or breastfeeding. For pregnant women, it should only be used if clearly needed and under strict medical supervision, as animal studies have shown potential harmful effects on the developing baby. For breastfeeding mothers, components of the medicine can pass into breast milk and may harm the baby, so it is likely unsafe. Always consult your doctor before using this medication if you are pregnant, planning to become pregnant, or breastfeeding.

Can SITAGLO M 100MG/500MG TAB be taken with other medications?

SITAGLO M can interact with certain medications. It is important to inform your doctor about all prescription, over-the-counter, vitamin, and herbal supplements you are taking. Interactions can occur with drugs like cimetidine, certain diuretics, corticosteroids, and some blood pressure medications. If you are taking insulin or sulfonylureas, your doctor may need to adjust their dosage to reduce the risk of low blood sugar. Avoid excessive alcohol consumption, as it can increase the risk of lactic acidosis.

What precautions should be taken while using SITAGLO M 100MG/500MG TAB?

Several precautions should be observed:

• Inform your doctor if you have kidney or liver disease, heart failure, or a history of pancreatitis.
• This medication is not suitable for individuals with Type 1 diabetes or diabetic ketoacidosis.
• Avoid or limit alcohol consumption due to an increased risk of lactic acidosis.
• If you are scheduled for surgery or diagnostic tests involving contrast dye, you may need to temporarily stop this medicine.
• Regular monitoring of blood sugar levels and kidney function is crucial.
• Stay well-hydrated to prevent dehydration.

What happens if a dose of SITAGLO M 100MG/500MG TAB is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should SITAGLO M 100MG/500MG TAB be stored?

Store SITAGLO M 100MG/500MG TAB in a closed container at room temperature, generally below 30°C (86°F). Keep it away from moisture, heat, and direct light. Ensure it is stored out of the reach of children and pets.