Zerodol Th Od 8

ZERODOL TH OD 8 is a medication manufactured by Ipca Laboratories Ltd., designed to manage painful inflammatory conditions associated with muscle spasms.

Name

• Brand Name: ZERODOL TH OD 8
• Common Name: Aceclofenac + Thiocolchicoside (Oral Disintegrating Capsule/Tablet)

Composition ZERODOL TH OD 8 contains a combination of two active ingredients:

• Aceclofenac (200 mg): A Non-Steroidal Anti-inflammatory Drug (NSAID) that works by blocking the production of certain chemicals (prostaglandins) in the body responsible for pain and inflammation.
• Thiocolchicoside (8 mg): A muscle relaxant that acts on the centers of the spinal cord and brain to relieve muscle stiffness and improve muscle movements.

Uses ZERODOL TH OD 8 is prescribed for adults to manage:

• Painful inflammatory conditions associated with muscle spasms.
• Musculoskeletal (bone) disorders such as osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis (inflammation of joints/bones in the spine).
• Pain due to muscle spasms associated with degenerative vertebral disorders, vertebral static problems, dorsal pain, low back pain, and torticollis (neck muscle contractions).
• It also helps reduce muscle stiffness and improve muscle movement.

Dosage and Administration ZERODOL TH OD 8 should be taken as advised by a doctor. It is typically taken with food to prevent an upset stomach. The capsule should be swallowed whole with a glass of water and not crushed, chewed, or broken. The doctor will determine the frequency and duration of treatment based on the patient's medical condition. For conditions like osteoarthritis, a typical dosage might be one tablet twice daily.

Side Effects Common side effects may include:

• Dizziness, drowsiness, tiredness.
• Nausea, vomiting, indigestion, heartburn, stomach pain, diarrhea, loss of appetite.
• Increased liver enzymes.

Serious side effects, though rare, warrant immediate medical attention and include severe allergic reactions (skin rash, swelling of face/lips/tongue, difficulty breathing), mouth ulcers, unexpected bruising or bleeding, and signs of liver damage (nausea, sudden weight loss, yellowing of eyes/skin).

Precautions

• Consult a doctor if pregnant, planning pregnancy, or breastfeeding, as it is generally not recommended during pregnancy (especially in the last trimester) and is contraindicated in breastfeeding women.
• Use with caution in patients with kidney diseases, liver diseases (severe liver failure is a contraindication), heart diseases (heart failure, high blood pressure, high cholesterol), diabetes mellitus, a history of stomach ulcers, or inflammatory bowel diseases (ulcerative colitis, Crohn's disease).
• Avoid if allergic to the medicine components or other painkillers.
• Do not take if you have asthma or varicella infection.
• Avoid alcohol and smoking during therapy.
• May cause dizziness or drowsiness; avoid driving or operating machinery if affected.
• Not recommended for children under 18 years of age.
• Long-term use may cause kidney damage.

Storage Store in a cool and dry place away from sunlight, ideally below 30°C. Keep out of sight and reach of children.

What is ZERODOL TH OD 8 used for?

ZERODOL TH OD 8 is primarily used to relieve pain and reduce inflammation associated with muscle spasms. It is prescribed for conditions such as degenerative vertebral disorders, vertebral static problems, dorsal pain, low back pain, and torticollis (neck muscle contractions). It also helps alleviate muscle stiffness, improves muscle movement, and can be used for painful inflammatory conditions like osteoarthritis, rheumatoid arthritis, and ankylosing spondylitis.

How does ZERODOL TH OD 8 work?

ZERODOL TH OD 8 is a combination medication containing Aceclofenac and Thiocolchicoside. Aceclofenac is a Non-Steroidal Anti-inflammatory Drug (NSAID) that works by blocking the production of certain chemical messengers (prostaglandins) in the body responsible for pain, inflammation, and swelling. Thiocolchicoside is a muscle relaxant that acts on the centers of the spinal cord and brain to relieve muscle stiffness and improve muscle movements by blocking specific chemical messengers (GABA) that cause painful muscle spasms.

What is the usual dosage of ZERODOL TH OD 8?

The dosage of ZERODOL TH OD 8 should be strictly as prescribed by your doctor, as it depends on your medical condition and how you respond to the medication. It is generally taken orally, usually once or twice a day, with or after a meal, swallowed whole with a glass of water to minimize stomach upset. Do not crush, chew, or break the capsule, and never exceed the prescribed dose.

What are the possible side effects of ZERODOL TH OD 8?

Common side effects may include diarrhea, dizziness, nausea, vomiting, stomach pain, heartburn, loss of appetite, increased liver enzymes, drowsiness, tiredness, visual disturbances, flatulence, and flushing. If these side effects persist or worsen, consult your doctor. More serious but rare side effects can include severe allergic reactions (skin rash, itching, swelling), mouth ulcers, peeling skin, difficulty breathing, unexpected bruising or bleeding, and signs of liver damage (such as yellowing of eyes and skin), which require immediate medical attention.

Is ZERODOL TH OD 8 safe during pregnancy or breastfeeding?

ZERODOL TH OD 8 is generally not recommended during pregnancy, especially in the last three months, as it may harm the fetus, potentially causing malformations, birth defects, kidney and heart problems, delaying labor, or leading to bleeding defects. Pregnant women should consult their doctor for safer alternatives. It is also contraindicated during breastfeeding because the medicine may pass into breast milk and cause adverse effects on the baby. Women of childbearing age should use suitable contraceptive methods while taking this medication.

Can ZERODOL TH OD 8 be taken with other medications?

ZERODOL TH OD 8 can interact with various medications. Taking it with other NSAIDs or anticoagulants (like warfarin) can increase the risk of stomach ulcers or bleeding. It may reduce the effectiveness of diuretics and interfere with blood pressure medications. Concomitant use with cyclosporine and tacrolimus can lead to kidney damage. It should not be taken within two weeks of mifepristone. Certain antibiotics (e.g., ciprofloxacin, ofloxacin) may increase the risk of fits. Always inform your doctor about all other medications you are taking, including over-the-counter drugs and herbal supplements, to avoid potential interactions.

What precautions should be taken while using ZERODOL TH OD 8?

Exercise caution if you have a history of kidney, liver, or heart conditions (including heart failure, high blood pressure, or high cholesterol), asthma, stomach ulcers, gastrointestinal bleeding, or epilepsy. This medicine is not recommended for children under 18 years of age. Due to potential side effects like dizziness, drowsiness, or vision problems, avoid driving or operating heavy machinery until you know how the medication affects you. Limit or avoid alcohol consumption as it can increase the risk of stomach irritation, bleeding, and excessive drowsiness.

What happens if a dose of ZERODOL TH OD 8 is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should ZERODOL TH OD 8 be stored?

Store ZERODOL TH OD 8 in a cool, dry place, away from direct sunlight. The ideal storage temperature is between 10ºC to 25ºC or below 30ºC. Keep the medicine out of the sight and reach of children.