Glyciphage Sr 850 Tablet

GLYCIPHAGE SR 850 TABLET

GLYCIPHAGE SR 850 TABLET is a medication manufactured by FRANCO-INDIAN PHARMACEUTICALS PVT LTD, primarily used for the management of Type 2 Diabetes Mellitus. It is a sustained-release formulation designed to provide consistent blood sugar control.

• Name:

  • Brand Name: Glyciphage SR 850 mg Tablet
  • Common Name: Metformin (as Metformin Hydrochloride)

• Composition: Each uncoated sustained-release tablet contains Metformin Hydrochloride I.P. 850 mg.

• Uses:

  • Management of Type 2 Diabetes Mellitus in adults, particularly when diet and exercise alone are insufficient to control blood glucose levels. It helps to lower glucose production in the liver, delay glucose absorption from the intestines, and increase the body's sensitivity to insulin.
  • Treatment of Polycystic Ovary Syndrome (PCOS) in women, by improving insulin sensitivity, lowering insulin and androgen levels, and helping to restore hormonal balance and regulate menstrual cycles.

• Dosage and Administration:

  • Take GLYCIPHAGE SR 850 TABLET orally, as directed by your doctor.
  • It is typically taken once or twice daily, with or after meals to minimize gastrointestinal side effects.
  • Swallow the tablet whole with a glass of water; do not crush, chew, or break it, as this can affect the medication's release.
  • The exact dosage and frequency will be determined by your doctor based on your medical condition and response to treatment.

• Side Effects:

  • Common Side Effects: Nausea, vomiting, diarrhea, abdominal pain/discomfort, loss of appetite, and a metallic taste in the mouth. These are usually mild and tend to resolve over time.
  • Serious (Rare) Side Effects: Lactic acidosis, a serious metabolic complication, can occur. Symptoms include deep or rapid breathing, persistent nausea, vomiting, severe tiredness, and stomach pain with muscle cramps. Prolonged use may also lead to vitamin B12 deficiency. Immediate medical attention is required for serious side effects.

• Precautions:

  • Contraindications: Do not take if you are allergic to metformin or any of its components, or if you have severe kidney disease, diabetic ketoacidosis, metabolic acidosis, or congestive heart failure.
  • Alcohol: Avoid alcohol consumption as it significantly increases the risk of lactic acidosis.
  • Medical Conditions: Inform your doctor if you have liver or kidney problems, dehydration, infections, uncontrolled diabetes, heart problems, or low levels of vitamin B12.
  • Pregnancy and Breastfeeding: Generally considered safe during pregnancy if prescribed by a doctor. Use with caution during breastfeeding as metformin passes into breast milk in small amounts.
  • Drug Interactions: Inform your doctor about all other medications, supplements, or herbal preparations you are taking, as they may interact with GLYCIPHAGE SR 850 TABLET (e.g., ibuprofen, celecoxib, salbutamol, terbutaline, furosemide, and iodine-containing contrast media).
  • Monitoring: Regular monitoring of blood sugar levels and kidney function is advised during treatment.

• Storage: Store in a cool and dry place, away from direct sunlight, moisture, and heat. Keep out of sight and reach of children. The recommended storage temperature is between 10ºC to 25ºC or below 30ºC.

Here are the most frequently asked questions about GLYCIPHAGE SR 850 TABLET:

What is GLYCIPHAGE SR 850 TABLET used for?

GLYCIPHAGE SR 850 TABLET is primarily used to treat type 2 diabetes mellitus, especially in adults who are overweight or obese and whose blood sugar levels are not adequately controlled by diet and exercise alone. It also helps prevent serious complications of diabetes such as kidney damage, blindness, and nerve issues. Additionally, it is used to treat Polycystic Ovary Syndrome (PCOS) in women, helping to restore hormonal balance and regulate menstrual cycles.

How does GLYCIPHAGE SR 850 TABLET work?

This medicine contains Metformin, which belongs to a class of anti-diabetic drugs called biguanides. It works by decreasing the amount of glucose produced by the liver and delaying the absorption of sugar from the intestines. It also enhances the body's sensitivity to insulin, a natural hormone that controls blood sugar levels, allowing muscles and fat tissues to utilize glucose more effectively. In PCOS, it improves insulin sensitivity, which helps to lower insulin and androgen levels.

What is the usual dosage for GLYCIPHAGE SR 850 TABLET?

GLYCIPHAGE SR 850 TABLET should be taken exactly as prescribed by your doctor, usually once or twice daily with food. It is important to swallow the tablet whole with a glass of water and not to chew or crush it. The exact dosage may vary depending on the severity of your condition and your response to the medication.

What are the possible side effects of GLYCIPHAGE SR 850 TABLET?

Common side effects can include nausea, vomiting, diarrhea, abdominal pain or discomfort, loss of appetite, and a metallic taste in the mouth. These often do not require medical attention and tend to resolve over time. A rare but serious side effect is lactic acidosis, characterized by symptoms such as stomach pain with muscle cramps, vomiting, reduced body temperature, and difficulty breathing, which requires immediate medical attention. Prolonged use may also lead to Vitamin B12 deficiency.

Is GLYCIPHAGE SR 850 TABLET safe during pregnancy or breastfeeding?

GLYCIPHAGE SR 850 TABLET is generally considered safe for use during pregnancy if prescribed by a doctor, though limited human studies are available. For breastfeeding mothers, caution is advised as Metformin can pass into breast milk in small quantities. It is recommended to consult your doctor if you are pregnant, planning to become pregnant, or breastfeeding.

Can GLYCIPHAGE SR 850 TABLET be taken with other medications?

GLYCIPHAGE SR 850 TABLET can interact with several medications. Inform your doctor about all medicines, supplements, or herbal preparations you are taking. Specific interactions may occur with certain cationic medicines (e.g., amiloride, digoxin), thiazide diuretics (e.g., hydrochlorothiazide), corticosteroids (e.g., prednisone), some pain relievers (e.g., ibuprofen), asthma medications (e.g., salbutamol), and diuretics (e.g., furosemide). If you are scheduled for an X-ray or scan involving iodine-containing contrast media, your doctor may advise you to temporarily stop taking Metformin.

What precautions should be taken while using GLYCIPHAGE SR 850 TABLET?

Avoid consuming alcohol with GLYCIPHAGE SR 850 TABLET, as it can significantly increase the risk of lactic acidosis. It is not recommended if you have severe kidney disease, diabetic ketoacidosis, or metabolic acidosis, or congestive heart failure. Inform your doctor if you have liver or kidney problems, dehydration, infections, uncontrolled diabetes, or low vitamin B12 levels. Regular monitoring of blood sugar levels and kidney function is important. Do not stop taking this medicine without consulting your doctor.

What happens if a dose of GLYCIPHAGE SR 850 TABLET is missed?

If you miss a dose of GLYCIPHAGE SR 850 TABLET, take it as soon as you remember with food. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should GLYCIPHAGE SR 850 TABLET be stored?

GLYCIPHAGE SR 850 TABLET should be stored in a cool, dry place, protected from direct sunlight, moisture, and heat. The storage temperature should ideally be between 10ºC and 25ºC or below 30ºC. Keep the medicine out of sight and reach of children.