Pregastar D 75/20mg Cap

PREGASTAR D 75/20MG CAP

PREGASTAR D 75/20MG CAP, manufactured by Lupin Ltd., is a combination medication designed for the management of neuropathic pain and related conditions.

• Name

  • Brand Name: PREGASTAR D 75/20MG CAP
  • Common Name: Pregabalin + Duloxetine

• Composition Each capsule contains:

  • Pregabalin: 75 mg
  • Duloxetine: 20 mg

• Uses PREGASTAR D 75/20MG CAP is primarily prescribed for the management of neuropathic pain (nerve pain) caused by various conditions, including:

  • Diabetic neuropathy
  • Fibromyalgia
  • Spinal cord injury
  • Shingles (post-herpetic neuralgia) It is also used in the treatment of depression and anxiety disorders, by helping to reduce pain signals and improve mood.

• Dosage and Administration Take PREGASTAR D 75/20MG CAP exactly as directed by your doctor. The capsule should be swallowed whole with a glass of water; do not cut, break, or chew it. It can be taken with or without food. To maintain consistent levels of the medicine in the body, it is essential to take it at the same time daily. Do not suddenly stop taking this medicine, as it may lead to withdrawal symptoms.

• Side Effects Common side effects may include:

  • Dizziness, drowsiness, headache
  • Nausea, dry mouth, constipation
  • Increased appetite, weight gain
  • Blurred vision, difficulty concentrating
  • Tingling or numbness, increased sweating
  • Reduced sex drive, painful or frequent urination

  More serious, though rare, side effects can include changes in mood or behavior, including suicidal thoughts. Seek immediate medical attention if you experience these symptoms.

• Precautions

  • Allergies: Do not take if you are allergic to pregabalin, duloxetine, or any other ingredients in the medicine.
  • Medical History: Inform your doctor if you have liver or kidney disease, seizures, mania, bipolar disorder, glaucoma, bleeding disorders, uncontrolled hypertension, or are at risk of hyponatremia.
  • Pregnancy and Breastfeeding: Consult your doctor if you are pregnant, planning a pregnancy, or breastfeeding. This medicine may be unsafe during pregnancy and is probably unsafe during breastfeeding.
  • Alcohol Consumption: Avoid or limit alcohol intake as it can increase dizziness, drowsiness, and the risk of liver damage.
  • Driving and Operating Machinery: This medicine may cause dizziness, drowsiness, and blurred vision. Avoid driving or operating heavy machinery until you know how it affects you.
  • Withdrawal Symptoms: Do not stop taking PREGASTAR D abruptly. Your doctor will gradually reduce the dosage to prevent withdrawal symptoms.
  • Drug Interactions: Inform your doctor about all other medicines, supplements, or herbal products you are currently taking to avoid potential interactions, especially with other antidepressants, psychiatric medicines, heart medicines, migraine medicines, and certain painkillers.
  • Children: Not recommended for use in children under 18 years of age.
  • Grapefruit: Avoid consuming grapefruit or grapefruit juice while on this medication.

• Storage Store PREGASTAR D 75/20MG CAP in dry conditions at room temperature (20-25°C). Keep it away from wet surfaces, direct sunlight, moisture, and humid conditions.

Here are the most frequently asked questions about PREGASTAR D 75/20MG CAP:

What is PREGASTAR D 75/20MG CAP used for?

PREGASTAR D 75/20MG CAP is a combination medication used to manage neuropathic pain, which includes conditions like diabetic neuropathy, fibromyalgia, and pain caused by spinal cord injury or other nerve damage. It is also used in the treatment of anxiety disorders and depression, particularly when associated with chronic pain.

How does PREGASTAR D 75/20MG CAP work?

This medicine contains two active ingredients: Pregabalin and Duloxetine. Pregabalin, an anticonvulsant, works by controlling calcium channels in overactive nerve cells, thereby reducing the transmission of pain signals. Duloxetine, a serotonin-norepinephrine reuptake inhibitor (SNRI), increases the levels of serotonin and norepinephrine, which are chemical messengers in the brain responsible for regulating pain and improving mood.

What is the usual dosage for PREGASTAR D 75/20MG CAP?

PREGASTAR D 75/20MG CAP is typically taken once or twice a day, with or without food, as prescribed by your doctor. It's crucial to take the medicine at the same time daily to maintain consistent levels in the body. Your doctor may start with a low dose and gradually increase it based on your response and tolerance. Do not exceed the prescribed dosage or stop the medication abruptly.

What are the possible side effects of PREGASTAR D 75/20MG CAP?

Common side effects can include drowsiness, dizziness, dry mouth, weight gain, blurred vision, constipation, nausea, headache, increased appetite, tingling or numbness, fatigue, and difficulty concentrating. More serious, but rare, side effects can include suicidal thoughts or severe allergic reactions. Peripheral edema (swelling in the limbs) and reduced sex drive have also been reported.

Is PREGASTAR D 75/20MG CAP safe during pregnancy or breastfeeding?

PREGASTAR D 75/20MG CAP is generally considered unsafe during pregnancy and breastfeeding. In pregnancy, it may cause fetal abnormalities, particularly if taken in the last trimester. Both Pregabalin and Duloxetine can be excreted in breast milk and may harm the nursing infant. It is essential to consult your doctor to discuss potential risks and benefits if you are pregnant, planning to conceive, or breastfeeding.

Can PREGASTAR D 75/20MG CAP be taken with other medications?

Taking PREGASTAR D 75/20MG CAP with other medications, especially central nervous system depressants (like benzodiazepines, opioids, or sedatives), can enhance sedative effects, leading to increased drowsiness and dizziness. It should not be taken with Monoamine Oxidase Inhibitors (MAOIs) due to the risk of serotonin syndrome. Always inform your doctor about all medicines, supplements, or herbal products you are currently taking to avoid potential interactions.

What precautions should be taken while taking PREGASTAR D 75/20MG CAP?

Avoid consuming alcohol while taking this medicine as it can increase dizziness and drowsiness. Do not drive or operate heavy machinery until you understand how the medicine affects you, as it can cause sleepiness, dizziness, and blurred vision. Inform your doctor if you have kidney or liver problems, a history of depression, mood changes, suicidal thoughts, seizures, glaucoma, or bleeding disorders. Do not stop taking the medication suddenly, as it can worsen symptoms or cause withdrawal effects.

What happens if a dose of PREGASTAR D 75/20MG CAP is missed?

If you miss a dose of PREGASTAR D 75/20MG CAP, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one. It is important to continue the treatment as prescribed to avoid worsening symptoms or withdrawal effects.

How should PREGASTAR D 75/20MG CAP be stored?

PREGASTAR D 75/20MG CAP should be stored in dry conditions at room temperature, typically between 20-25°C. Keep it away from wet surfaces, direct sunlight, and humid conditions. Always ensure it is stored out of the reach of children.