Xilingio 25/5 Mg Tab

Here is a detailed product description for XILINGIO 25/5 MG TAB:

XILINGIO 25/5 MG TAB

• Name: Xilingio 25/5mg Tablet. (Manufacturer: Torrent Pharmaceuticals Ltd.)

• Composition: Each tablet contains Empagliflozin 25 mg and Linagliptin 5 mg.

  • Empagliflozin is a sodium-glucose co-transporter 2 (SGLT2) inhibitor that works by increasing the removal of glucose through urine.
  • Linagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that increases insulin release and reduces glucose production, especially after meals.

• Uses: Xilingio 25/5mg Tablet is primarily used for the treatment of Type 2 diabetes mellitus in adults. It is prescribed when diet and exercise alone are insufficient to control blood sugar levels. This medication also helps to reduce the risk of cardiovascular death and hospitalizations due to heart failure in adults with type 2 diabetes and established cardiovascular disease. It may also be used in the treatment of chronic kidney disease in adults with reduced kidney function.

• Dosage and Administration: The tablet should be taken orally once daily, with or without food, at the same time each day for best results. It should be swallowed whole and not crushed, chewed, or broken.

• Side Effects: Common side effects may include:

  • Urinary tract infections (UTIs).
  • Nasopharyngitis (inflammation of the throat and nasal passages).
  • Frequent urination.
  • Low blood sugar level (hypoglycemia), especially when used with other antidiabetic medicines.
  • Cough, rash, itching.
  • Genital mycotic infections (fungal infections in the genital area).
  • Nausea, diarrhea, abdominal discomfort, back pain.

• Precautions:

  • Pregnancy and Breastfeeding: Generally not advised during pregnancy or breastfeeding; consult a doctor.
  • Alcohol: Avoid alcohol consumption as it can heighten the risk of low blood sugar or dehydration and can lead to fluctuations in blood sugar levels.
  • Kidney/Liver Problems: Use with caution in patients with kidney disease; it is not recommended for severe kidney or liver disease.
  • Interactions: Inform your doctor about all medicines, supplements, or herbals you are taking, especially insulin, sulfonylureas, and diuretics, as they may increase the risk of hypoglycemia or volume depletion.
  • Hydration: Stay well-hydrated, especially during physical activity or in hot weather.
  • Not for Type 1 diabetes.

• Storage: Store at room temperature, away from moisture, excessive heat, and direct light. Keep out of reach of children and pets. Do not use past the expiration date.

What is Xilingio 25/5 MG Tablet used for?

Xilingio 25/5 MG Tablet is a combination medication primarily used in adults to manage Type 2 Diabetes Mellitus. It helps to control high blood sugar levels when diet and exercise alone are not sufficient. Additionally, it can reduce the risk of cardiovascular death and hospitalization due to heart failure in adults with Type 2 diabetes who also have established heart disease.

How does Xilingio 25/5 MG Tablet work?

This medicine contains two active ingredients: Empagliflozin (25 mg) and Linagliptin (5 mg). Empagliflozin works by blocking a protein in the kidneys called sodium-glucose co-transporter 2 (SGLT-2), which prevents the kidneys from reabsorbing glucose. This leads to increased glucose removal from the body through urine. Linagliptin works by inhibiting the enzyme dipeptidyl peptidase-4 (DPP-4), which helps the body produce more insulin when blood sugar levels are high (especially after meals) and reduces glucose production by the liver.

What is the usual dosage for Xilingio 25/5 MG Tablet?

Xilingio 25/5 MG Tablet should be taken once daily, with or without food, as directed by your doctor. It is recommended to take it at the same time each day for best results. Do not stop taking the medication or adjust the dosage without consulting your doctor.

What are the possible side effects of Xilingio 25/5 MG Tablet?

Common side effects may include urinary tract infections, nasopharyngitis (inflammation of the throat and nasal passages), upper respiratory tract infections, genital fungal infections, increased urination, headache, diarrhea, back pain, and joint pain. If taken with other diabetes medications like insulin or sulfonylureas, there is an increased risk of low blood sugar (hypoglycemia).

Is Xilingio 25/5 MG Tablet safe during pregnancy or breastfeeding?

Xilingio 25/5 MG Tablet is generally not recommended during pregnancy or breastfeeding. If you are pregnant, planning to become pregnant, or breastfeeding, you should consult your doctor for alternative diabetes treatments. Animal studies have shown potential harmful effects on a developing baby.

Can Xilingio 25/5 MG Tablet be taken with other medications?

Yes, Xilingio 25/5 MG Tablet can be used with other diabetes medications if prescribed by your doctor. However, it's crucial to monitor your blood sugar closely, as combining medications, especially with insulin or sulfonylureas, can increase the risk of hypoglycemia. Diuretic medications (water pills) may also increase the risk of volume depletion when taken with Xilingio. Inform your doctor about all medicines, supplements, or herbal products you are currently taking.

What precautions should be taken while using Xilingio 25/5 MG Tablet?

Caution is advised if you have kidney or liver problems; the medication is contraindicated in severe kidney disease or if you are on dialysis. You should stay well-hydrated, especially during physical activity or in hot weather, to prevent fluid loss. Avoid excessive alcohol intake, as it can affect blood sugar control and increase the risk of low blood sugar or dehydration. This medicine is not for Type 1 diabetes or diabetic ketoacidosis.

What happens if a dose of Xilingio 25/5 MG Tablet is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and resume your regular dosing schedule. Do not take a double dose to compensate for the missed one.

How should Xilingio 25/5 MG Tablet be stored?

Xilingio 25/5 MG Tablet should be stored at room temperature, ideally below 30°C (86°F), away from moisture, excessive heat, and direct light. Keep it out of reach of children and pets, and do not use it past its expiration date.