Zomelis Sr 100

ZOMELIS SR 100 by ERIS LIFESCIENCES LTD

Name

• Brand Name: ZOMELIS SR 100
• Common Name: Vildagliptin (as the active ingredient)

Composition

• Active Ingredient: Each sustained-release (SR) tablet contains Vildagliptin 100 mg.
• Class: Dipeptidyl peptidase-4 (DPP-4) inhibitor.

Uses

ZOMELIS SR 100 is primarily prescribed for the management of Type 2 Diabetes Mellitus in adults. It is used when diet and exercise alone are insufficient to control blood sugar levels. This medication can be used alone or in combination with other antidiabetic drugs like metformin, sulfonylureas, or insulin to help achieve better glycemic control. By effectively controlling blood sugar, it helps prevent serious long-term complications associated with diabetes, such as kidney damage, blindness, nerve problems, and reduced risk of heart attack or stroke.

Dosage and Administration

ZOMELIS SR 100 is an oral, sustained-release tablet typically taken once daily. It can be administered with or without food. Tablets should be swallowed whole with a glass of water and should not be crushed or chewed. For optimal effectiveness, it is recommended to take the medicine at the same time each day to maintain consistent medication levels in the body. The dosage will be determined by a healthcare professional based on individual condition and blood glucose levels.

Side Effects

Common Side Effects:

• Nausea, vomiting, diarrhea, abdominal pain, loss of appetite, metallic taste
• Hypoglycemia (low blood sugar), headache, dizziness, weakness, fatigue
• Upper respiratory tract infection, urinary tract infection, nasopharyngitis
• Skin rash, itching, tremors, constipation

Serious Side Effects:

• Liver problems (e.g., jaundice, elevated liver enzymes)
• Pancreatitis (severe and persistent abdominal pain)
• Severe allergic reactions (e.g., anaphylaxis, angioedema)
• Blood disorders (e.g., thrombocytopenia, leukopenia)
• Muscle pain or weakness (myalgia), vision changes

Symptoms of hypoglycemia may include sweating, shaking, dizziness, confusion, lightheadedness, and dry mouth.

Precautions

• Inform your doctor about any history of kidney disease, liver problems (not recommended for severe hepatic impairment), heart failure, or pancreatitis before starting treatment.
• ZOMELIS SR 100 is generally not recommended for use in pregnant or breastfeeding women.
• Avoid alcohol consumption as it can significantly affect blood glucose levels.
• This medication may cause dizziness; exercise caution when driving or operating machinery until you know how it affects you.
• Disclose all other medications, including prescription, over-the-counter drugs, and herbal supplements, to your doctor to avoid potential drug interactions, especially with other antidiabetic medicines which may increase the risk of hypoglycemia.
• Regular monitoring of blood sugar levels, kidney, and liver function is advised.
• Not indicated for Type 1 Diabetes Mellitus or diabetic ketoacidosis.
• Do not stop taking the medicine abruptly without consulting your doctor.
• Not recommended for children and adolescents under 18 years of age.
• Use with caution in elderly patients, as they may be more susceptible to side effects.

Storage

Store ZOMELIS SR 100 in a cool and dry place, protected from light and moisture, typically below 25°C or 30°C. Keep out of the reach of children and pets. Do not keep outdated medicine.

ZOMELIS SR 100 by ERIS LIFESCIENCES LTD is a medication primarily used in the management of type 2 diabetes mellitus. It contains vildagliptin as its active ingredient, a dipeptidyl peptidase-4 (DPP-4) inhibitor.

What is ZOMELIS SR 100 used for?

ZOMELIS SR 100 is used to manage type 2 diabetes mellitus in adults. It helps control high blood sugar levels, typically alongside a healthy diet and regular exercise. It can be prescribed alone or in combination with other antidiabetic medications when lifestyle modifications are not enough.

How does ZOMELIS SR 100 work?

ZOMELIS SR 100 contains vildagliptin, which is a DPP-4 inhibitor. It works by preventing the breakdown of natural substances in the body called incretin hormones (such as GLP-1 and GIP). These hormones increase insulin release from the pancreas when blood sugar levels are high and decrease the production of glucagon (a hormone that raises blood sugar) by the liver. The "SR" in ZOMELIS SR 100 signifies a sustained-release formulation, meaning the medication is released slowly over an extended period.

What is the usual dosage of ZOMELIS SR 100?

The typical starting dose is 100mg taken orally once daily. Your doctor may adjust the dosage based on your condition and response to treatment. It can be taken with or without food, but it's important to take it at the same time each day for consistent effectiveness. Swallow the tablet whole; do not crush or chew it.

What are the possible side effects of ZOMELIS SR 100?

Common side effects may include nausea, vomiting, diarrhea, abdominal pain, headache, dizziness, weakness, loss of appetite, metallic taste, upper respiratory tract infections, urinary tract infections, skin rash, itching, and hypoglycemia (low blood sugar). More serious but less common side effects can include liver problems (e.g., jaundice, elevated liver enzymes), pancreatitis, or severe allergic reactions.

Is ZOMELIS SR 100 safe during pregnancy or breastfeeding?

ZOMELIS SR 100 is generally not recommended during pregnancy unless considered essential by your doctor, as there is limited information on its safety and animal studies have shown potential harmful effects on the developing baby. It is also not recommended during breastfeeding, as it may pass into breast milk and potentially harm the baby.

Can ZOMELIS SR 100 be taken with other medications?

ZOMELIS SR 100 can interact with certain medications. Concomitant use with other antidiabetic medicines, such as sulfonylureas or insulin, may increase the risk of low blood sugar (hypoglycemia). It's crucial to inform your doctor about all prescription, over-the-counter medications, and herbal supplements you are taking, including water pills, corticosteroids, thyroxine, digoxin, warfarin, and simvastatin, to avoid potential drug interactions.

What precautions should be taken with ZOMELIS SR 100?

Before starting ZOMELIS SR 100, inform your doctor about any pre-existing medical conditions, especially kidney or liver problems, heart failure, or a history of pancreatitis. It is not recommended for individuals with type 1 diabetes or diabetic ketoacidosis. Regular monitoring of blood sugar levels, and possibly kidney and liver function, is important during treatment. Limit alcohol intake, as it can affect blood glucose levels.

What happens if a dose of ZOMELIS SR 100 is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one.

How should ZOMELIS SR 100 be stored?

Store ZOMELIS SR 100 in a dry place at room temperature, typically below 25°C or 30°C. Keep it protected from light and moisture, and ensure it is out of the reach of children and pets. Always check the expiry date on the packaging.