Clopivas Ap 150 Mg Tablet (15 Tab)

CLOPIVAS AP 150 MG TABLET

CLOPIVAS AP 150 MG TABLET is a combination medication manufactured by Cipla Ltd., primarily used to prevent blood clots.

• Composition: Each tablet contains Aspirin IP 150 mg and Clopidogrel Bisulphate IP equivalent to Clopidogrel 75 mg. Both are antiplatelet agents (blood thinners) that work by preventing platelets from sticking together and forming harmful blood clots in blood vessels.

• Uses: This medicine is prescribed for the prevention of heart attack and stroke. It is also used in the management of acute coronary syndrome (ACS) and unstable angina, and to prevent blood clots after procedures like angioplasty or stent placement. CLOPIVAS AP 150 Tablet helps maintain free blood flow, thereby reducing the risk of cardiovascular events, deep vein thrombosis, and pulmonary embolism.

• Dosage and Administration: The recommended dose is typically one tablet once daily, or as advised by a doctor. It can be taken with or without food, though taking it with food may help avoid stomach upset. Tablets should be swallowed whole and not chewed, crushed, or broken. Do not stop taking this medicine without consulting a doctor.

• Side Effects: Common side effects include abdominal pain, indigestion, diarrhoea, easy bruising, nosebleeds, dizziness, and blurry vision. Serious side effects can include severe allergic reactions, gastrointestinal bleeding or ulcers, and a rare blood disorder called Thrombotic Thrombocytopenic Purpura (TTP).

• Precautions: CLOPIVAS AP 150 MG TABLET increases the risk of bleeding, so caution is advised during activities that may cause injury. Alcohol consumption should be limited or avoided as it can increase the risk of stomach bleeding. Inform your doctor about any pre-existing medical conditions, allergies to aspirin or clopidogrel, or other medications being taken. It is generally not recommended during pregnancy or breastfeeding, or for children under 16 years of age. Caution is also advised for patients with liver or kidney disease.

• Storage: Store in a cool and dry place, away from direct sunlight, and out of sight and reach of children. Store below 30°C.

CLOPIVAS AP 150 MG TABLET is a combination medication containing Aspirin (150 mg) and Clopidogrel (75 mg), primarily used to prevent blood clot formation. It is classified as an antiplatelet agent or blood thinner.

What is CLOPIVAS AP 150 MG Tablet used for?

CLOPIVAS AP 150 MG Tablet is used to prevent serious cardiovascular events such as heart attacks and strokes. It is prescribed for individuals at high risk, those with a history of heart attack or stroke, and patients undergoing procedures like angioplasty with stent placement or coronary artery bypass graft. It also helps in managing acute coronary syndrome and unstable angina.

How does CLOPIVAS AP 150 MG Tablet work?

CLOPIVAS AP 150 MG Tablet works by combining two antiplatelet medicines: Aspirin and Clopidogrel. Aspirin inhibits an enzyme called cyclooxygenase (COX), which reduces the production of substances that cause platelets to clump together. Clopidogrel, a prodrug, is activated in the body and then selectively inhibits the binding of adenosine diphosphate (ADP) to its receptor on platelets, preventing their activation and aggregation. Together, they prevent platelets from sticking to each other, thereby decreasing the formation of harmful blood clots and ensuring free blood flow.

What is the usual dosage of CLOPIVAS AP 150 MG Tablet?

The recommended dose is typically one tablet once daily, or as advised by your doctor. It can be taken with or without food, but taking it with food may help prevent stomach upset. It's crucial to follow your doctor's instructions regarding dosage and duration and not to chew, crush, or break the tablet.

What are the possible side effects of CLOPIVAS AP 150 MG Tablet?

Common side effects include abdominal pain, indigestion, diarrhea, easy bruising, and nosebleeds. Other possible side effects are headache, dizziness, and blurry vision. Most common side effects usually resolve over time. However, if side effects are persistent, severe, or you experience unusual or prolonged bleeding (e.g., black tarry stools, blood in urine), severe allergic reactions, or signs of liver/kidney dysfunction, seek medical attention immediately.

Is CLOPIVAS AP 150 MG Tablet safe during pregnancy or breastfeeding?

CLOPIVAS AP 150 MG Tablet is generally not recommended for use during pregnancy as it may pose risks to the developing baby. It is also not recommended for breastfeeding mothers, as the medicine may pass into breast milk and potentially affect the infant. Pregnant or breastfeeding individuals should consult their doctor to weigh the benefits and potential risks or discuss alternative therapies. In some cases, low doses of aspirin (less than 150mg daily) may be considered safe during breastfeeding, but a doctor's advice is essential.

Can CLOPIVAS AP 150 MG Tablet be taken with other medications?

CLOPIVAS AP 150 MG Tablet can interact with various medications, increasing the risk of bleeding or affecting its efficacy. It's crucial to inform your doctor about all medicines, supplements, or herbal products you are currently taking.

• Anticoagulants (blood thinners) like warfarin or heparin: Concomitant use significantly increases the risk of bleeding.
• Other nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen or naproxen: May increase the risk of gastrointestinal bleeding and stomach ulcers.
• Proton-pump inhibitors (PPIs) like omeprazole or esomeprazole: Can reduce the antiplatelet effect of clopidogrel. Your doctor may consider alternative acid-reducing agents.
• Antacids: May reduce the effect of aspirin.
• Antipsychotic medicines like sertraline or paroxetine, and steroids: Can increase the risk of bleeding in the stomach and intestines.
• Ciclosporin or tacrolimus: Concomitant use with NSAIDs may increase nephrotoxic effects.

What precautions should be taken?

• Bleeding risk: This medicine increases the risk of bleeding. Be careful during activities like shaving, brushing teeth, or using sharp objects. Inform your doctor or dentist before any surgical or dental procedures.
• Allergies: Do not take this medicine if you are allergic to aspirin, clopidogrel, or any of its components.
• Medical conditions: Inform your doctor if you have underlying conditions such as bleeding disorders (e.g., hemophilia, stomach ulcer, bleeding in the head or bowel), severe liver or kidney disease, gout, or respiratory problems like asthma or nasal polyps.
• Alcohol consumption: Avoid excessive alcohol intake, as it can increase the risk of gastrointestinal bleeding.
• Driving: CLOPIVAS AP 150 MG Tablet may cause dizziness, sleepiness, or blurred vision. Avoid driving or operating machinery if you experience these symptoms.
• Do not stop abruptly: Do not stop taking the medicine without consulting your doctor, as premature discontinuation can increase the risk of heart attack or stroke.

What happens if a dose is missed?

If you miss a dose, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

How should CLOPIVAS AP 150 MG Tablet be stored?

Store CLOPIVAS AP 150 MG Tablet in a cool and dry place, away from direct heat or moisture and sunlight, at a temperature below 30°C. Keep it out of the sight and reach of children and pets.