Sistal Ap Tab

SISTAL AP TAB

SISTAL AP TAB, manufactured by Bestochem Formulations, is a combination medication designed to provide relief from pain and inflammation.

• Composition Each tablet typically contains:

  • Aceclofenac (100 mg)
  • Paracetamol (325 mg)
  • Trypsin Chymotrypsin (50000 AU or 5000 IU) Aceclofenac, a Non-Steroidal Anti-Inflammatory Drug (NSAID), and Paracetamol, an analgesic, work by blocking chemical messengers (prostaglandins) that cause pain and inflammation. Trypsin Chymotrypsin is a proteolytic enzyme that helps break down abnormal proteins at the site of inflammation, thereby reducing swelling and aiding in tissue repair.

• Uses SISTAL AP TAB is prescribed for the management of pain and inflammation associated with various conditions, including:

  • Osteoarthritis
  • Rheumatoid Arthritis
  • Ankylosing Spondylitis
  • Spondylosis and Spondyloarthritis
  • Other ortho-degenerative disorders It is also effective for musculoskeletal pain, back pain, dental pain, post-operative pain, and soft tissue injuries like sprains and strains.

• Dosage and Administration This medication should be taken as advised by a doctor, typically once or twice daily. It is recommended to take SISTAL AP TAB with food to minimize stomach upset. The tablet should be swallowed whole, not chewed, crushed, or broken. Do not exceed the prescribed dose or duration.

• Side Effects Common side effects may include:

  • Nausea
  • Vomiting
  • Stomach pain or abdominal discomfort
  • Indigestion or heartburn
  • Diarrhoea
  • Loss of appetite
  • Dizziness
  • Rash If side effects persist or worsen, medical attention should be sought.

• Precautions

  • Allergies: Do not take if allergic to any of its components or other anti-inflammatory painkillers.
  • Pregnancy & Breastfeeding: Not recommended for pregnant or breastfeeding women without consulting a doctor, as it may cause moderate side effects.
  • Alcohol: Avoid alcohol consumption as it may increase drowsiness and the risk of stomach bleeding.
  • Driving/Machinery: May cause dizziness and drowsiness; exercise caution when driving or operating machinery.
  • Organ Impairment: Not recommended for severe liver or kidney impairment, and caution is advised for mild to moderate cases.
  • Heart Conditions: Not recommended for patients with severe heart problems, a history of heart attack, or blood circulation issues. Use with caution in patients with high blood pressure, angina, or blood clots.
  • Gastrointestinal Issues: Caution is advised for individuals with a history of peptic ulcers, gastrointestinal bleeding, or inflammation of the intestines.
  • Children: Not recommended for children as safety and efficacy have not been established.
  • Drug Interactions: Inform your doctor about all other medications being taken, especially SSRIs, diuretics, ACE inhibitors, lithium, and anti-tubercular medicines.

• Storage Store SISTAL AP TAB in a cool, dry place, away from direct sunlight and heat. Keep out of reach of children and pets.

Here are some frequently asked questions about SISTAL AP TAB by BESTOCHEM FORMULATIONS:

What is Sistal AP Tablet used for?

Sistal AP Tablet is a combination medicine used to relieve pain and inflammation associated with various conditions. It is effective in managing pain and swelling in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, spondylosis, spondyloarthritis, and other ortho-degenerative disorders. It can also be used for muscle pain, back pain, toothache, throat pain, and post-operative pain.

How does Sistal AP Tablet work?

Sistal AP Tablet is composed of Aceclofenac, Paracetamol, and Trypsin Chymotrypsin. Aceclofenac, a non-steroidal anti-inflammatory drug (NSAID), and Paracetamol, an analgesic and antipyretic, work by blocking the effect of chemical messengers called prostaglandins. Prostaglandins are responsible for causing pain, inflammation, and fever by inhibiting cyclooxygenase (COX) enzymes. Trypsin Chymotrypsin is a combination of enzymes that break down abnormal proteins at the site of inflammation, thereby reducing swelling and accelerating the healing process by increasing blood supply.

What is the usual dosage of Sistal AP Tablet?

The dosage and duration of Sistal AP Tablet should be followed as prescribed by your doctor, depending on your medical condition. It is generally recommended to take it with food to avoid stomach upset.

What are the possible side effects of Sistal AP Tablet?

Common side effects of Sistal AP Tablet may include nausea, vomiting, stomach pain, indigestion, heartburn, loss of appetite, abdominal discomfort, dizziness, and diarrhea. Most of these side effects are usually mild and temporary, resolving over time. If they persist or worsen, it is important to consult your doctor.

Is Sistal AP Tablet safe during pregnancy or breastfeeding?

Sistal AP Tablet may be unsafe to use during pregnancy, especially in the last 3 months, as it could cause harmful effects on the developing baby and may lead to reduced labor. Information regarding its use during breastfeeding is limited, and it is generally not recommended. It is crucial to consult your doctor if you are pregnant or breastfeeding, or planning to become pregnant, before taking this medication.

Can Sistal AP Tablet be taken with other medications?

Sistal AP Tablet can interact with certain medications. Inform your doctor about all the medicines you are currently taking. Interactions can occur with anticoagulants (like warfarin or heparin), antiplatelets (like clopidogrel or aspirin), selective serotonin reuptake inhibitors (SSRIs) which may increase the risk of gastrointestinal bleeding, diuretics, ACE inhibitors, lithium, methotrexate, and mifepristone. Avoid taking it with any other medicine containing acetaminophen without consulting your doctor.

What precautions should be taken while using Sistal AP Tablet?

Do not take Sistal AP Tablet if you are allergic to any of its components or have a history of severe heart problems, active or recurring peptic ulcer, gastrointestinal bleeding, severe liver or kidney impairment. Use with caution if you have high blood pressure, heart problems, high cholesterol, diabetes, asthma, or bowel problems. Avoid consuming alcohol while taking this medicine, as it can increase drowsiness, dizziness, and the risk of stomach bleeding. Sistal AP Tablet may cause dizziness and drowsiness, so exercise caution when driving or operating machinery. It is not recommended for children as its safety and efficacy have not been established.

What happens if a dose of Sistal AP Tablet is missed?

If you miss a dose of Sistal AP Tablet, take it as soon as you remember. However, if it is almost time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not double the dose to make up for a missed one, as this may increase the risk of side effects.

How should Sistal AP Tablet be stored?

Sistal AP Tablet should be stored in a cool and dry place, away from direct sunlight and moisture. Keep it out of the reach and sight of children. It should be stored at temperatures between 10ºC to 25ºC or below 30ºC.